Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50021703
TargetProtein cereblon(Human)TBA
LigandPNGBDBM50643720(CHEMBL5574408)
Affinity DataIC50: 0.900nMAssay Description:Binding affinity to GST-tagged human CRBN by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCREB-binding protein(Human)TBA
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataKd:  0.900nMAssay Description:Binding affinity to CBP (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCREB-binding protein(Human)TBA
LigandPNGBDBM50269849(CHEMBL4076748)
Affinity DataKd:  1.10nMAssay Description:Binding affinity to CBP (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein cereblon(Human)TBA
LigandPNGBDBM50643726(CHEMBL5566094)
Affinity DataIC50: 1.10nMAssay Description:Binding affinity to GST-tagged human CRBN by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProtein cereblon(Human)TBA
LigandPNGBDBM50643725(CHEMBL5575548)
Affinity DataIC50: 1.10nMAssay Description:Binding affinity to GST-tagged human CRBN by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataKd:  1.20nMAssay Description:Binding affinity to p300 (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein cereblon(Human)TBA
LigandPNGBDBM50643724(CHEMBL5565362)
Affinity DataIC50: 1.30nMAssay Description:Binding affinity to GST-tagged human CRBN by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProtein cereblon(Human)TBA
LigandPNGBDBM50643721(CHEMBL5575700)
Affinity DataIC50: 1.30nMAssay Description:Binding affinity to GST-tagged human CRBN by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50269849(CHEMBL4076748)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to p300 (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCREB-binding protein(Human)TBA
LigandPNGBDBM50602864(INOBRODIB | Inobrodib | Ccs 1477 | Ccs1477 | CCS-1...)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to CBP (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50602864(INOBRODIB | Inobrodib | Ccs 1477 | Ccs1477 | CCS-1...)
Affinity DataKd:  1.70nMAssay Description:Binding affinity to p300 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProtein cereblon(Human)TBA
LigandPNGBDBM50643722(CHEMBL5564627)
Affinity DataIC50: 1.80nMAssay Description:Binding affinity to GST-tagged human CRBN by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCREB-binding protein(Human)TBA
LigandPNGBDBM50467836(CHEMBL4282264)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of CBP BHC domain (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProtein cereblon(Human)TBA
LigandPNGBDBM50643723(CHEMBL5575710)
Affinity DataIC50: 2.80nMAssay Description:Binding affinity to GST-tagged human CRBN by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataKd:  4.60nMAssay Description:Binding affinity to BRD4 (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCREB-binding protein(Human)TBA
LigandPNGBDBM50643720(CHEMBL5574408)
Affinity DataIC50: 7.10nMAssay Description:Binding affinity to CBP (unknown origin) by fluorescence Polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50643720(CHEMBL5574408)
Affinity DataIC50: 7.70nMAssay Description:Binding affinity to p300 (unknown origin) by fluorescence Polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50643722(CHEMBL5564627)
Affinity DataIC50: 9.5nMAssay Description:Binding affinity to p300 (unknown origin) by fluorescence Polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50467836(CHEMBL4282264)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of P300 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCREB-binding protein(Human)TBA
LigandPNGBDBM50643722(CHEMBL5564627)
Affinity DataIC50: 11nMAssay Description:Binding affinity to CBP (unknown origin) by fluorescence Polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50643726(CHEMBL5566094)
Affinity DataIC50: 13nMAssay Description:Binding affinity to p300 (unknown origin) by fluorescence Polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCREB-binding protein(Human)TBA
LigandPNGBDBM50643721(CHEMBL5575700)
Affinity DataIC50: 13nMAssay Description:Binding affinity to CBP (unknown origin) by fluorescence Polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50643721(CHEMBL5575700)
Affinity DataIC50: 13nMAssay Description:Binding affinity to p300 (unknown origin) by fluorescence Polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCREB-binding protein(Human)TBA
LigandPNGBDBM50643726(CHEMBL5566094)
Affinity DataIC50: 15nMAssay Description:Binding affinity to CBP (unknown origin) by fluorescence Polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50643723(CHEMBL5575710)
Affinity DataIC50: 18nMAssay Description:Binding affinity to p300 (unknown origin) by fluorescence Polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCREB-binding protein(Human)TBA
LigandPNGBDBM50643723(CHEMBL5575710)
Affinity DataIC50: 19nMAssay Description:Binding affinity to CBP (unknown origin) by fluorescence Polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCREB-binding protein(Human)TBA
LigandPNGBDBM188519(SGC-CBP30)
Affinity DataKd:  21nMAssay Description:Binding affinity to CBP (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM188519(SGC-CBP30)
Affinity DataKd:  32nMAssay Description:Binding affinity to p300 (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50643725(CHEMBL5575548)
Affinity DataIC50: 35nMAssay Description:Binding affinity to p300 (unknown origin) by fluorescence Polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50643724(CHEMBL5565362)
Affinity DataIC50: 44nMAssay Description:Binding affinity to p300 (unknown origin) by fluorescence Polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCREB-binding protein(Human)TBA
LigandPNGBDBM50643724(CHEMBL5565362)
Affinity DataIC50: 49nMAssay Description:Binding affinity to CBP (unknown origin) by fluorescence Polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCREB-binding protein(Human)TBA
LigandPNGBDBM50643725(CHEMBL5575548)
Affinity DataIC50: 52nMAssay Description:Binding affinity to CBP (unknown origin) by fluorescence Polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCREB-binding protein(Human)TBA
LigandPNGBDBM50151663(CHEMBL3774655)
Affinity DataKd:  151nMAssay Description:Binding affinity to CBP (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50151663(CHEMBL3774655)
Affinity DataKd:  167nMAssay Description:Binding affinity to p300 (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50269849(CHEMBL4076748)
Affinity DataKd:  200nMAssay Description:Binding affinity to BRD4 (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50602864(INOBRODIB | Inobrodib | Ccs 1477 | Ccs1477 | CCS-1...)
Affinity DataKd:  222nMAssay Description:Binding affinity to BRD4 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50346552(CHEMBL1797936)
Affinity DataKi:  400nMAssay Description:Binding affinity to p300 (unknown origin) using 3H-Acetyl CoA as substrate assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM188519(SGC-CBP30)
Affinity DataKd:  850nMAssay Description:Binding affinity to BRD4 (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50151663(CHEMBL3774655)
Affinity DataKd:  5.60E+3nMAssay Description:Binding affinity to BRD4 (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed