Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50021091
TargetHistone-lysine N-methyltransferase NSD2(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50598859(CHEMBL5200945)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of NSD2 PWWP1 domain (unknown origin) by NanoBRET target engagement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase NSD2(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50598859(CHEMBL5200945)
Affinity DataKd:  91nMAssay Description:Binding affinity to NSD2 PWWP1 domain (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase NSD2(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50598859(CHEMBL5200945)
Affinity DataIC50: 104nMAssay Description:Inhibition of NSD2 PWWP1 domain (unknown origin) by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase NSD3(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50555101(CHEMBL4778517)
Affinity DataIC50: 200nMAssay Description:Inhibition of NSD3 PWWP1 domain (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed