Compile Data Set for Download or QSAR
Report error Found 62 Enz. Inhib. hit(s) with all data for entry = 50021212
LigandPNGBDBM456149(US10723723, Example 35)
Affinity DataIC50: 1nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638354(CHEMBL5561980)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 3 to 8 mins by whole cell manual patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM423199(US10501449, Example 2-I)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 3 to 8 mins by whole cell manual patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM456221((R)-6-(5-(((2-hydroxy-2- (4-methyl-1-oxo-1,3- dihy...)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM423212(US10501449, Example 83-I)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 3 to 8 mins by whole cell manual patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638363(CHEMBL5558589)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 3 to 8 mins by whole cell manual patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638352(CHEMBL5556822)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 3 to 8 mins by whole cell manual patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638347(CHEMBL5560628)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638347(CHEMBL5560628)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 3 to 8 mins by whole cell manual patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM423198(US10501449, Example 1-I)
Affinity DataIC50: 11nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 3 to 8 mins by whole cell manual patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638350(CHEMBL5563632)
Affinity DataIC50: 12nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 3 to 8 mins by whole cell manual patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638343(CHEMBL5560486)
Affinity DataIC50: 13nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 3 to 8 mins by whole cell manual patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638363(CHEMBL5558589)
Affinity DataIC50: 13nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638354(CHEMBL5561980)
Affinity DataIC50: 13nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM423198(US10501449, Example 1-I)
Affinity DataIC50: 14nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM423199(US10501449, Example 2-I)
Affinity DataIC50: 15nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638357(CHEMBL5562228)
Affinity DataIC50: 15nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM456207((R)-6-(3-(difluoromethyl)- 4-(((2-hydroxy-2-(4- me...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638358(CHEMBL5557656)
Affinity DataIC50: 16nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM423231(6-(4-(((3R,4R)-4- hydroxy-3-(4- methyl-1-oxo-1,3- ...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 3 to 8 mins by whole cell manual patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638349(CHEMBL5523625)
Affinity DataIC50: 17nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM423263(4-methyl-6-(4-((2- methyl-5-(4-methyl-1- oxo-1,3- ...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638348(CHEMBL5527997)
Affinity DataIC50: 18nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 3 to 8 mins by whole cell manual patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM423263(4-methyl-6-(4-((2- methyl-5-(4-methyl-1- oxo-1,3- ...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 3 to 8 mins by whole cell manual patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638361(CHEMBL5560085)
Affinity DataIC50: 23nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM423212(US10501449, Example 83-I)
Affinity DataIC50: 24nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM423231(6-(4-(((3R,4R)-4- hydroxy-3-(4- methyl-1-oxo-1,3- ...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM423203(US10501449, Example 22-I)
Affinity DataIC50: 25nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 3 to 8 mins by whole cell manual patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM423203(US10501449, Example 22-I)
Affinity DataIC50: 26nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638359(CHEMBL5560876)
Affinity DataIC50: 30nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638344(CHEMBL5556159)
Affinity DataIC50: 32nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638350(CHEMBL5563632)
Affinity DataIC50: 36nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638345(CHEMBL5558564)
Affinity DataIC50: 37nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 3 to 8 mins by whole cell manual patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638351(CHEMBL5560041)
Affinity DataIC50: 46nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638352(CHEMBL5556822)
Affinity DataIC50: 52nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638356(CHEMBL5555211)
Affinity DataIC50: 57nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638362(CHEMBL5517758)
Affinity DataIC50: 57nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 3 to 8 mins by whole cell manual patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638343(CHEMBL5560486)
Affinity DataIC50: 59nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638345(CHEMBL5558564)
Affinity DataIC50: 61nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638362(CHEMBL5517758)
Affinity DataIC50: 62nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638346(CHEMBL5549890)
Affinity DataIC50: 74nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638360(CHEMBL5555792)
Affinity DataIC50: 84nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638348(CHEMBL5527997)
Affinity DataIC50: 86nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638353(CHEMBL5523626)
Affinity DataIC50: 430nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638355(CHEMBL5556245)
Affinity DataIC50: 620nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM423212(US10501449, Example 83-I)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of OCT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM423212(US10501449, Example 83-I)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of MATE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM423212(US10501449, Example 83-I)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of OCT2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile salt export pump(Human)TBA
LigandPNGBDBM423212(US10501449, Example 83-I)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of BSEP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM423212(US10501449, Example 83-I)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Kir 7.1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
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