Compile Data Set for Download or QSAR
Report error Found 65 Enz. Inhib. hit(s) with all data for entry = 50021903
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50598138BDBM50598138(CHEMBL5204399)
Affinity DataIC50: 94nMAssay Description:Inhibition of C-terminal his-6 tagged SARS CoV-2 PL protease expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 496864BDBM496864(SARS-CoV-2 PLpro Inhibitor, 94 | US20240166598, Ex...)
Affinity DataIC50: 113nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 496864BDBM496864(SARS-CoV-2 PLpro Inhibitor, 94 | US20240166598, Ex...)
Affinity DataKd:  113nMAssay Description:Binding affinity to N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells assessed as dissociation const...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 496862BDBM496862(SARS-CoV-2 PLpro Inhibitor, 92 | US20240166598, Ex...)
Affinity DataIC50: 210nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645932BDBM50645932(CHEMBL5591637)
Affinity DataIC50: 260nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645928BDBM50645928(CHEMBL5590755)
Affinity DataIC50: 320nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 496856BDBM496856(SARS-CoV-2 PLpro Inhibitor, 86 | US20240166598, Ex...)
Affinity DataIC50: 330nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645906BDBM50645906(CHEMBL5594376)
Affinity DataIC50: 330nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676181BDBM676181((1R,3S)-3-(((5-(3-((R)-1- (5-(azetidin-3-ylamino)-...)
Affinity DataIC50: 360nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 496859BDBM496859(SARS-CoV-2 PLpro Inhibitor, 89 | US20240166598, Co...)
Affinity DataIC50: 370nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 496843BDBM496843(SARS-CoV-2 PLpro Inhibitor, 73 | US20240166598, Co...)
Affinity DataKd:  370nMAssay Description:Binding affinity to N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells assessed as dissociation const...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645921BDBM50645921(CHEMBL5591371)
Affinity DataIC50: 380nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 496842BDBM496842(SARS-CoV-2 PLpro Inhibitor, 72 | US20240166598, Co...)
Affinity DataIC50: 390nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676184BDBM676184(5-(azetidin-3-yloxy)-N- ((R)-1-(3-(5-((((1S,3R)-3-...)
Affinity DataIC50: 430nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645947BDBM50645947(CHEMBL5583933)
Affinity DataIC50: 470nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645929BDBM50645929(CHEMBL5591613)
Affinity DataIC50: 490nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645945BDBM50645945(CHEMBL5594740)
Affinity DataIC50: 500nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645927BDBM50645927(CHEMBL5592166)
Affinity DataIC50: 550nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 496843BDBM496843(SARS-CoV-2 PLpro Inhibitor, 73 | US20240166598, Co...)
Affinity DataIC50: 560nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645944BDBM50645944(CHEMBL5593811)
Affinity DataIC50: 560nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645933BDBM50645933(CHEMBL5595950)
Affinity DataIC50: 570nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645939BDBM50645939(CHEMBL5591278)
Affinity DataIC50: 600nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645946BDBM50645946(CHEMBL5592606)
Affinity DataIC50: 600nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645948BDBM50645948(CHEMBL5594403)
Affinity DataIC50: 620nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645905BDBM50645905(CHEMBL5583811)
Affinity DataIC50: 650nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590411BDBM50590411(CHEMBL5182315)
Affinity DataIC50: 670nMAssay Description:Inhibition of C-terminal his-tagged SARS CoV-2 PL protease (1564 to 1876 residues) expressed in Escherichia coli BL21 (DE3) cells using ISG15-AMC as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590417BDBM50590417(CHEMBL5173886)
Affinity DataIC50: 670nMAssay Description:Inhibition of C-terminal his-tagged SARS CoV-2 PL protease (1564 to 1876 residues) expressed in Escherichia coli BL21 (DE3) cells using ISG15-AMC as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645923BDBM50645923(CHEMBL5591703)
Affinity DataIC50: 690nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645930BDBM50645930(CHEMBL5590148)
Affinity DataIC50: 750nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645920BDBM50645920(CHEMBL5594581)
Affinity DataIC50: 790nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676183BDBM676183((R)-5-(azetidin-3-yloxy)- 2-methyl-N-(1-(3-(5- (py...)
Affinity DataIC50: 810nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645919BDBM50645919(CHEMBL5591014)
Affinity DataIC50: 820nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645922BDBM50645922(CHEMBL5592435)
Affinity DataIC50: 820nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645904BDBM50645904(CHEMBL5584015)
Affinity DataIC50: 920nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645926BDBM50645926(CHEMBL5589924)
Affinity DataIC50: 960nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676182BDBM676182((R)-5-(azetidin-3-yloxy)- N-(1-(3-(5- ((cyclopenty...)
Affinity DataIC50: 960nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645918BDBM50645918(CHEMBL5590536)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645911BDBM50645911(CHEMBL5589705)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645925BDBM50645925(CHEMBL5592351)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645914BDBM50645914(CHEMBL5589680)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645934BDBM50645934(CHEMBL5591155)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645937BDBM50645937(CHEMBL5594045)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645941BDBM50645941(CHEMBL5583810)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 115160BDBM115160(acridine-3,6-diamine;sulfuric acid;hydrate | Profl...)
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of SARS CoV-2 PL proteaseMore data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645907BDBM50645907(CHEMBL5592713)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 496870BDBM496870(SARS-CoV-2 PLpro Inhibitor, 100 | US20240166598, E...)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645942BDBM50645942(CHEMBL5595528)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645931BDBM50645931(CHEMBL5592033)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31524BDBM31524(Naphthalene and Benzamide Derivative, 25 | 5-amino...)
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645910BDBM50645910(CHEMBL5591998)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of N-terminal his-tagged SARS CoV-2 PL protease (1564 to 1878 residues) expressed in BL21 (DE3) cells using Z-RLRGG-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
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