Compile Data Set for Download or QSAR
maximum 50k data
Found 24 Enz. Inhib. hit(s) with all data for entry = 50035558
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025953(6-Imidazo[1,5-a]pyridin-5-yl-hexanoic acid | CGS-1...)
Affinity DataIC50:  3.20nMAssay Description:In vitro inhibitory activity against thromboxane A2 synthetase with lysed human platelets as the enzyme source.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025970(6-Imidazo[1,5-a]pyridin-5-yl-hex-2-enoic acid | CH...)
Affinity DataIC50:  4.80nMAssay Description:In vitro inhibition of thromboxane A2 synthetase from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025966(7-Imidazo[1,5-a]pyridin-5-yl-heptanoic acid | CHEM...)
Affinity DataIC50:  5.20nMAssay Description:In vitro inhibition of thromboxane A2 synthetase from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025952(5-[4-(1H-Tetrazol-5-yl)-butyl]-imidazo[1,5-a]pyrid...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibition of thromboxane A2 synthetase from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025951(8-Imidazo[1,5-a]pyridin-5-yl-2-methyl-oct-2-enoic ...)
Affinity DataIC50:  19nMAssay Description:In vitro inhibition of thromboxane A2 synthetase from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025955(5-[5-(1H-Tetrazol-5-yl)-pentyl]-imidazo[1,5-a]pyri...)
Affinity DataIC50:  19nMAssay Description:In vitro inhibition of thromboxane A2 synthetase from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025967(6-Imidazo[1,5-a]pyridin-5-yl-hexanoic acid hydroxy...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of thromboxane A2 synthetase from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025961(8-Imidazo[1,5-a]pyridin-5-yl-octanoic acid | CHEMB...)
Affinity DataIC50:  21nMAssay Description:In vitro inhibition of thromboxane A2 synthetase from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025965(5-Imidazo[1,5-a]pyridin-5-yl-penta-2,4-dienoic aci...)
Affinity DataIC50:  28nMAssay Description:In vitro inhibition of thromboxane A2 synthetase from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025954(8-Imidazo[1,5-a]pyridin-5-yl-oct-2-enoic acid | CH...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of thromboxane A2 synthetase from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025959(5-Imidazo[1,5-a]pyridin-5-yl-pentanoic acid | CHEM...)
Affinity DataIC50:  41nMAssay Description:In vitro inhibition of thromboxane A2 synthetase from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025969(6-Imidazo[1,5-a]pyridin-5-yl-hexanoic acid amide |...)
Affinity DataIC50:  77nMAssay Description:In vitro inhibition of thromboxane A2 synthetase from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025964(6-Imidazo[1,5-a]pyridin-5-yl-hexanoic acid methyla...)
Affinity DataIC50:  270nMAssay Description:In vitro inhibition of thromboxane A2 synthetase from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025960(6-Imidazo[1,5-a]pyridin-5-yl-hexan-1-ol; hydrochlo...)
Affinity DataIC50:  280nMAssay Description:In vitro inhibition of thromboxane A2 synthetase from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025957(6-Imidazo[1,5-a]pyridin-5-yl-hexanoic acid ethyl e...)
Affinity DataIC50:  330nMAssay Description:In vitro inhibition of thromboxane A2 synthetase from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025971(5-Imidazo[1,5-a]pyridin-8-yl-pentanoic acid | CHEM...)
Affinity DataIC50:  390nMAssay Description:In vitro inhibition of thromboxane A2 synthetase from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025958(6-Imidazo[1,5-a]pyridin-5-yl-hexanoic acid dimethy...)
Affinity DataIC50:  550nMAssay Description:In vitro inhibition of thromboxane A2 synthetase from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025968(6-Imidazo[1,5-a]pyridin-5-yl-hexanenitrile; hydroc...)
Affinity DataIC50:  630nMAssay Description:In vitro inhibition of thromboxane A2 synthetase from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025962(5-Imidazo[1,5-a]pyridin-6-yl-pentanoic acid | CHEM...)
Affinity DataIC50:  3.30E+3nMAssay Description:In vitro inhibition of thromboxane A2 synthetase from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025956(5-Heptyl-imidazo[1,5-a]pyridine | CHEMBL45294)
Affinity DataIC50:  3.30E+3nMAssay Description:In vitro inhibition of thromboxane A2 synthetase from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025963(5-Imidazo[1,5-a]pyridin-7-yl-pentanoic acid | CHEM...)
Affinity DataIC50:  4.70E+3nMAssay Description:In vitro inhibition of thromboxane A2 synthetase from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025953(6-Imidazo[1,5-a]pyridin-5-yl-hexanoic acid | CGS-1...)
Affinity DataIC50:  1.00E+4nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025950(6-(3-Methyl-imidazo[1,5-a]pyridin-5-yl)-hexanoic a...)
Affinity DataIC50:  2.50E+4nMAssay Description:In vitro inhibition of thromboxane A2 synthetase from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025953(6-Imidazo[1,5-a]pyridin-5-yl-hexanoic acid | CGS-1...)
Affinity DataIC50:  1.00E+5nMAssay Description:In vitro inhibitory activity against prostacyclin synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed