Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50023428
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
University of Colorado Anschutz Medical Campus

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4814BDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  19nMAssay Description:Competitive binding affinity to AMPKalpha1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
University of Colorado Anschutz Medical Campus

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4814BDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  89nMAssay Description:Competitive binding affinity to AMPKalpha2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
University of Colorado Anschutz Medical Campus

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 379177BDBM379177(US10266549, Example 88 | US10266549, Example 171a ...)
Affinity DataIC50: 400nMAssay Description:Inhibition of AMPKalpha1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlycogen synthase kinase-3 beta(Human)
University of Colorado Anschutz Medical Campus

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50267626BDBM50267626(AZ-11548415 | AZD-1080)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed