Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50023251
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 642550BDBM642550(US20230416221, Compound 26)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661060BDBM50661060(CHEMBL6150992)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 642551BDBM642551(US20230416221, Compound 27)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661062BDBM50661062(CHEMBL6163025)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 642554BDBM642554(US20230416221, Compound 30)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 642552BDBM642552(US20230416221, Compound 28)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661065BDBM50661065(CHEMBL6133414)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661061BDBM50661061(CHEMBL6145090)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 642556BDBM642556(US20230416221, Compound 36)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 642561BDBM642561(US20230416221, Compound 42)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 642566BDBM642566(US20230416221, Compound 56)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 642558BDBM642558(US20230416221, Compound 39)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 642562BDBM642562(US20230416221, Compound 44)
Affinity DataIC50: 7nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661064BDBM50661064(CHEMBL6163487)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661058BDBM50661058(CHEMBL6143494)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 9(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 642551BDBM642551(US20230416221, Compound 27)
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK9 in human MCF7 cells assessed as reduction in phosphorylation of RNA polymerase II at Ser2 residue incubated for 4 hrs by immunoblo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661054BDBM50661054(CHEMBL6173831)
Affinity DataIC50: 11nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553483BDBM50553483(CHEMBL4756595 | US20230416221, Compound BAY1251152)
Affinity DataIC50: 13nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 642564BDBM642564(US20230416221, Compound 49)
Affinity DataIC50: 13nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661057BDBM50661057(CHEMBL6168890)
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661066BDBM50661066(CHEMBL6147995)
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661059BDBM50661059(CHEMBL6169899)
Affinity DataIC50: 22nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661063BDBM50661063(CHEMBL6134370)
Affinity DataIC50: 38nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661052BDBM50661052(CHEMBL6144922)
Affinity DataIC50: 38nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 642565BDBM642565(US20230416221, Compound 50)
Affinity DataIC50: 57nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 642563BDBM642563(US20230416221, Compound 48)
Affinity DataIC50: 59nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 9(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661052BDBM50661052(CHEMBL6144922)
Affinity DataIC50: 100nMAssay Description:Binding affinity to CDK9 in HEK293T cells by split luciferase complementation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661055BDBM50661055(CHEMBL6134488)
Affinity DataIC50: 120nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 4/6(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 642551BDBM642551(US20230416221, Compound 27)
Affinity DataIC50: 172nMAssay Description:Inhibition of CDK4/CDK6 in human MCF7 cells assessed as reduction in phosphorylation of Rb at S807/811 residue incubated for 4 hrs by immunoblotting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661056BDBM50661056(CHEMBL6172698)
Affinity DataIC50: 211nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 7(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 642551BDBM642551(US20230416221, Compound 27)
Affinity DataIC50: 377nMAssay Description:Inhibition of CDK7 in human MCF7 cells assessed as reduction in phosphorylation of RNA polymerase II at Ser5 residue incubated for 4 hrs by immunoblo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 1(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 642551BDBM642551(US20230416221, Compound 27)
Affinity DataIC50: 617nMAssay Description:Inhibition of CDK1 in human MCF7 cells assessed as reduction in phosphorylation of PP1alpha at T320 residue incubated for 4 hrs by immunoblotting ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661053BDBM50661053(CHEMBL6150541)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length wildtype human CDK9/Cyclin K extracted from baculovirus infected Sf9 cells using RNA poly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed