TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
Pennsylvania State University
Curated by ChEMBL
Pennsylvania State University
Curated by ChEMBL
Affinity DataKi: 0.190nMAssay Description:Inhibitor constant of compound for plasmodium falciparum dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
Pennsylvania State University
Curated by ChEMBL
Pennsylvania State University
Curated by ChEMBL
Affinity DataKi: 0.190nMAssay Description:Thermodynamic dissociation constant of compound for mutant T46S E. coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibitor constant of compound for mutant S108 N plasmodium falciparum i dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Dissociation rate constant of compound for mutant T46N Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Dissociation rate constant of compound for mutant T46A Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibitor constant of compound for mutant T46S E. coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKd: 1.40nMAssay Description:Dissociation rate constant of compound for mutant T46N Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKd: 220nMAssay Description:Dissociation rate constant of compound for wild type Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKd: 13nMAssay Description:Inhibitor constant of compound for mutant T46A E. coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKd: 2.40E+3nMAssay Description:Dissociation rate constant of compound for mutant T46S Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKd: 16nMAssay Description:Thermodynamic dissociation constant of compound for mutant T46A E. coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKd: 2.00E+3nMAssay Description:Thermodynamic dissociation constant of compound for mutant T46N E. coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKd: 1.5nMAssay Description:Thermodynamic dissociation constant of compound for mutant T46S E. coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKd: 243nMAssay Description:Dissociation rate constant of compound for wild type Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair