Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50000776
TargetEpidermal growth factor receptor(Human)
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) using Tyr 4 peptide as substrate in presence of ATP by Z-LYTE kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260359(CHEMBL4079658)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) using Tyr 4 peptide as substrate in presence of ATP by Z-LYTE kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260361(CHEMBL4066170)
Affinity DataIC50: 10nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) using Tyr 4 peptide as substrate in presence of ATP by Z-LYTE kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260362(CHEMBL4072620)
Affinity DataIC50: 18nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) using Tyr 4 peptide as substrate in presence of ATP by Z-LYTE kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260360(CHEMBL4103912)
Affinity DataIC50: 166nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using Tyr 4 peptide as substrate in presence of ATP by Z-LYTE kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260360(CHEMBL4103912)
Affinity DataIC50: 166nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using Tyr 4 peptide as substrate in presence of ATP by Z-LYTE kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260363(CHEMBL4087538)
Affinity DataIC50: 174nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using Tyr 4 peptide as substrate in presence of ATP by Z-LYTE kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260363(CHEMBL4087538)
Affinity DataIC50: 175nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using Tyr 4 peptide as substrate in presence of ATP by Z-LYTE kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 225nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using Tyr 4 peptide as substrate in presence of ATP by Z-LYTE kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260359(CHEMBL4079658)
Affinity DataIC50: 318nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using Tyr 4 peptide as substrate in presence of ATP by Z-LYTE kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260361(CHEMBL4066170)
Affinity DataIC50: 357nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using Tyr 4 peptide as substrate in presence of ATP by Z-LYTE kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260362(CHEMBL4072620)
Affinity DataIC50: 595nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using Tyr 4 peptide as substrate in presence of ATP by Z-LYTE kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2020
Entry Details Article
PubMed