Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50000776
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) using Tyr 4 peptide as substrate in presence of ATP by Z-LYTE kinase assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260359(CHEMBL4079658)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) using Tyr 4 peptide as substrate in presence of ATP by Z-LYTE kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260361(CHEMBL4066170)
Affinity DataIC50:  10nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) using Tyr 4 peptide as substrate in presence of ATP by Z-LYTE kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260362(CHEMBL4072620)
Affinity DataIC50:  18nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) using Tyr 4 peptide as substrate in presence of ATP by Z-LYTE kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260360(CHEMBL4103912)
Affinity DataIC50:  166nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using Tyr 4 peptide as substrate in presence of ATP by Z-LYTE kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260360(CHEMBL4103912)
Affinity DataIC50:  166nMAssay Description:Inhibition of Varicella-Zoster virus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260363(CHEMBL4087538)
Affinity DataIC50:  174nMAssay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260363(CHEMBL4087538)
Affinity DataIC50:  175nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using Tyr 4 peptide as substrate in presence of ATP by Z-LYTE kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50:  225nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using Tyr 4 peptide as substrate in presence of ATP by Z-LYTE kinase assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260359(CHEMBL4079658)
Affinity DataIC50:  318nMAssay Description:Inhibition of human alpha DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260361(CHEMBL4066170)
Affinity DataIC50:  357nMAssay Description:Inhibition of human delta DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260362(CHEMBL4072620)
Affinity DataIC50:  595nMAssay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed