Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50007944
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514279(CHEMBL4527655)
Affinity DataIC50: 0.257nMAssay Description:Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514280(CHEMBL4586663)
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514280(CHEMBL4586663)
Affinity DataIC50: 0.708nMAssay Description:Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514287(CHEMBL4532671)
Affinity DataIC50: 0.955nMAssay Description:Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514293(CHEMBL4515212)
Affinity DataIC50: 1nMAssay Description:Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514292(CHEMBL4533964)
Affinity DataIC50: 1nMAssay Description:Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514283(CHEMBL4524872)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514284(CHEMBL4483006)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514282(CHEMBL4543096)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514287(CHEMBL4532671)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50238741(CHEBI:31638 | Faslodex | Fulvestrant | ICI-182780 ...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514281(CHEMBL4516021)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514279(CHEMBL4527655)
Affinity DataIC50: 1.90nMAssay Description:Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514286(CHEMBL4448178)
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514286(CHEMBL4448178)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514290(CHEMBL4578883)
Affinity DataIC50: 2.70nMAssay Description:Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514285(CHEMBL4436707)
Affinity DataIC50: 3nMAssay Description:Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514292(CHEMBL4533964)
Affinity DataIC50: 3.10nMAssay Description:Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514282(CHEMBL4543096)
Affinity DataIC50: 3.5nMAssay Description:Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514290(CHEMBL4578883)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514293(CHEMBL4515212)
Affinity DataIC50: 4.30nMAssay Description:Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514294(CHEMBL4564385)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514289(CHEMBL4538085)
Affinity DataIC50: 5.20nMAssay Description:Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514278(CHEMBL4436415)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514295(CHEMBL4440649)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514284(CHEMBL4483006)
Affinity DataIC50: 7.40nMAssay Description:Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514288(CHEMBL4464171)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514289(CHEMBL4538085)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514291(CHEMBL4447374)
Affinity DataIC50: 10nMAssay Description:Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514278(CHEMBL4436415)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514295(CHEMBL4440649)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514294(CHEMBL4564385)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514283(CHEMBL4524872)
Affinity DataIC50: 28nMAssay Description:Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514288(CHEMBL4464171)
Affinity DataIC50: 64nMAssay Description:Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed