Compile Data Set for Download or QSAR
Report error Found 158 Enz. Inhib. hit(s) with all data for entry = 50010094
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535083BDBM50535083(CHEMBL4460676)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535084BDBM50535084(CHEMBL3546703)
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535112BDBM50535112(CHEMBL4439328)
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535097BDBM50535097(CHEMBL4561098)
Affinity DataIC50: 5nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535093BDBM50535093(CHEMBL4472827)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535107BDBM50535107(CHEMBL4468047)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535089BDBM50535089(CHEMBL4528289)
Affinity DataIC50: 16nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535105BDBM50535105(CHEMBL4455268)
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535088BDBM50535088(CHEMBL4584789)
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535114BDBM50535114(CHEMBL4583779)
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535118BDBM50535118(CHEMBL4460283)
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535102BDBM50535102(CHEMBL4570588)
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535104BDBM50535104(CHEMBL4556378)
Affinity DataIC50: 32nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535087BDBM50535087(CHEMBL4458845)
Affinity DataIC50: 32nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535114BDBM50535114(CHEMBL4583779)
Affinity DataIC50: 32nMAssay Description:Inhibition of N-terminal-6His-tagged full length human Aurora B expressed in baculovirus using 5FAM-PKA-tide as substrate after 120 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535111BDBM50535111(CHEMBL4590420)
Affinity DataIC50: 40nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535117BDBM50535117(CHEMBL4437415)
Affinity DataIC50: 50nMAssay Description:Inhibition of N-terminal-6His-tagged full length human Aurora B expressed in baculovirus using 5FAM-PKA-tide as substrate after 120 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535101BDBM50535101(CHEMBL4444533)
Affinity DataIC50: 50nMAssay Description:Inhibition of N-terminal-6His-tagged full length human Aurora B expressed in baculovirus using 5FAM-PKA-tide as substrate after 120 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535117BDBM50535117(CHEMBL4437415)
Affinity DataIC50: 50nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535097BDBM50535097(CHEMBL4561098)
Affinity DataIC50: 50nMAssay Description:Inhibition of N-terminal-6His-tagged full length human Aurora B expressed in baculovirus using 5FAM-PKA-tide as substrate after 120 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535086BDBM50535086(CHEMBL4469408)
Affinity DataIC50: 50nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535110BDBM50535110(CHEMBL4570285)
Affinity DataIC50: 50nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535084BDBM50535084(CHEMBL3546703)
Affinity DataIC50: 63nMAssay Description:Inhibition of N-terminal-6His-tagged full length human Aurora B expressed in baculovirus using 5FAM-PKA-tide as substrate after 120 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535082BDBM50535082(CHEMBL4466696)
Affinity DataIC50: 63nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535115BDBM50535115(CHEMBL4453218)
Affinity DataIC50: 63nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535113BDBM50535113(CHEMBL4473150)
Affinity DataIC50: 63nMAssay Description:Inhibition of N-terminal-6His-tagged full length human Aurora B expressed in baculovirus using 5FAM-PKA-tide as substrate after 120 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535085BDBM50535085(CHEMBL4455093)
Affinity DataIC50: 63nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535112BDBM50535112(CHEMBL4439328)
Affinity DataIC50: 63nMAssay Description:Inhibition of N-terminal-6His-tagged full length human Aurora B expressed in baculovirus using 5FAM-PKA-tide as substrate after 120 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535097BDBM50535097(CHEMBL4561098)
Affinity DataIC50: 63nMAssay Description:Inhibition of SYK in human B cells assessed as suppression of anti-IgM-induced CD69 surface expression preincubated for 30 mins followed by anti-IgM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535083BDBM50535083(CHEMBL4460676)
Affinity DataIC50: 79nMAssay Description:Inhibition of N-terminal-6His-tagged full length human Aurora B expressed in baculovirus using 5FAM-PKA-tide as substrate after 120 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535092BDBM50535092(CHEMBL4469541)
Affinity DataIC50: 79nMAssay Description:Inhibition of N-terminal-6His-tagged full length human Aurora B expressed in baculovirus using 5FAM-PKA-tide as substrate after 120 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535095BDBM50535095(CHEMBL4468195)
Affinity DataIC50: 79nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535103BDBM50535103(CHEMBL4448695)
Affinity DataIC50: 79nMAssay Description:Inhibition of N-terminal-6His-tagged full length human Aurora B expressed in baculovirus using 5FAM-PKA-tide as substrate after 120 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535099BDBM50535099(CHEMBL4526150)
Affinity DataIC50: 79nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535112BDBM50535112(CHEMBL4439328)
Affinity DataIC50: 79nMAssay Description:Inhibition of SYK in human B cells assessed as suppression of anti-IgM-induced CD69 surface expression preincubated for 30 mins followed by anti-IgM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535102BDBM50535102(CHEMBL4570588)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal-6His-tagged full length human Aurora B expressed in baculovirus using 5FAM-PKA-tide as substrate after 120 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535116BDBM50535116(CHEMBL4455149)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535100BDBM50535100(CHEMBL4439653)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal-6His-tagged full length human Aurora B expressed in baculovirus using 5FAM-PKA-tide as substrate after 120 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535104BDBM50535104(CHEMBL4556378)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal-6His-tagged full length human Aurora B expressed in baculovirus using 5FAM-PKA-tide as substrate after 120 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535098BDBM50535098(CHEMBL4571227)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535082BDBM50535082(CHEMBL4466696)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal-6His-tagged full length human Aurora B expressed in baculovirus using 5FAM-PKA-tide as substrate after 120 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535093BDBM50535093(CHEMBL4472827)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal-6His-tagged full length human Aurora B expressed in baculovirus using 5FAM-PKA-tide as substrate after 120 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535082BDBM50535082(CHEMBL4466696)
Affinity DataIC50: 100nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535085BDBM50535085(CHEMBL4455093)
Affinity DataIC50: 100nMAssay Description:Inhibition of SYK in human B cells assessed as suppression of anti-IgM-induced CD69 surface expression preincubated for 30 mins followed by anti-IgM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535101BDBM50535101(CHEMBL4444533)
Affinity DataIC50: 126nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535087BDBM50535087(CHEMBL4458845)
Affinity DataIC50: 126nMAssay Description:Inhibition of SYK in human B cells assessed as suppression of anti-IgM-induced CD69 surface expression preincubated for 30 mins followed by anti-IgM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535084BDBM50535084(CHEMBL3546703)
Affinity DataIC50: 126nMAssay Description:Inhibition of SYK in human B cells assessed as suppression of anti-IgM-induced CD69 surface expression preincubated for 30 mins followed by anti-IgM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535096BDBM50535096(CHEMBL4560963)
Affinity DataIC50: 158nMAssay Description:Inhibition of N-terminal-6His-tagged full length human Aurora B expressed in baculovirus using 5FAM-PKA-tide as substrate after 120 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535092BDBM50535092(CHEMBL4469541)
Affinity DataIC50: 158nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535083BDBM50535083(CHEMBL4460676)
Affinity DataIC50: 158nMAssay Description:Inhibition of SYK in human B cells assessed as suppression of anti-IgM-induced CD69 surface expression preincubated for 30 mins followed by anti-IgM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
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