Compile Data Set for Download or QSAR
Report error Found 61 Enz. Inhib. hit(s) with all data for entry = 50011903
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50143059BDBM50143059(CHEMBL3758746)
Affinity DataEC50:  22nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552354BDBM50552354(CHEMBL4799902)
Affinity DataEC50:  42nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552342BDBM50552342(CHEMBL4787053)
Affinity DataEC50:  56nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552349BDBM50552349(CHEMBL4792152)
Affinity DataEC50:  58nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552347BDBM50552347(CHEMBL4798021)
Affinity DataEC50:  58nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552343BDBM50552343(CHEMBL4746530)
Affinity DataEC50:  63nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552347BDBM50552347(CHEMBL4798021)
Affinity DataEC50:  65nMAssay Description:Positive allosteric modulation of human mGluR4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552330BDBM50552330(CHEMBL4745982)
Affinity DataEC50:  74nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552348BDBM50552348(CHEMBL4764083)
Affinity DataEC50:  77nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552352BDBM50552352(CHEMBL4796783)
Affinity DataEC50:  78nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552333BDBM50552333(CHEMBL4760570)
Affinity DataEC50:  89nMAssay Description:Positive allosteric modulation of human mGluR4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552346BDBM50552346(CHEMBL4777502)
Affinity DataEC50:  93nMAssay Description:Positive allosteric modulation of human mGluR4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552347BDBM50552347(CHEMBL4798021)
Affinity DataEC50:  98nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552341BDBM50552341(CHEMBL4782646)
Affinity DataEC50:  99nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552346BDBM50552346(CHEMBL4777502)
Affinity DataEC50:  106nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552348BDBM50552348(CHEMBL4764083)
Affinity DataEC50:  113nMAssay Description:Positive allosteric modulation of human mGluR4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552348BDBM50552348(CHEMBL4764083)
Affinity DataEC50:  114nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552330BDBM50552330(CHEMBL4745982)
Affinity DataEC50:  128nMAssay Description:Positive allosteric modulation of human mGluR4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552346BDBM50552346(CHEMBL4777502)
Affinity DataEC50:  132nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552331BDBM50552331(CHEMBL4795139)
Affinity DataEC50:  175nMAssay Description:Positive allosteric modulation of human mGluR4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552330BDBM50552330(CHEMBL4745982)
Affinity DataEC50:  180nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552342BDBM50552342(CHEMBL4787053)
Affinity DataEC50:  187nMAssay Description:Positive allosteric modulation of human mGluR4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552330BDBM50552330(CHEMBL4745982)
Affinity DataEC50:  189nMAssay Description:Positive allosteric modulation of mGluR8 (unknown origin) by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552342BDBM50552342(CHEMBL4787053)
Affinity DataEC50:  201nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552354BDBM50552354(CHEMBL4799902)
Affinity DataEC50:  212nMAssay Description:Positive allosteric modulation of human mGluR4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552345BDBM50552345(CHEMBL4788523)
Affinity DataEC50:  217nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552358BDBM50552358(CHEMBL4787147)
Affinity DataEC50:  220nMAssay Description:Negative allosteric modulation of human mGluR1 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552332BDBM50552332(CHEMBL4797971)
Affinity DataEC50:  229nMAssay Description:Positive allosteric modulation of human mGluR4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552349BDBM50552349(CHEMBL4792152)
Affinity DataEC50:  266nMAssay Description:Positive allosteric modulation of human mGluR4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552343BDBM50552343(CHEMBL4746530)
Affinity DataEC50:  267nMAssay Description:Positive allosteric modulation of human mGluR4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552354BDBM50552354(CHEMBL4799902)
Affinity DataEC50:  302nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552356BDBM50552356(CHEMBL4800540)
Affinity DataEC50:  306nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552349BDBM50552349(CHEMBL4792152)
Affinity DataEC50:  372nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552333BDBM50552333(CHEMBL4760570)
Affinity DataEC50:  377nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552332BDBM50552332(CHEMBL4797971)
Affinity DataEC50:  400nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552343BDBM50552343(CHEMBL4746530)
Affinity DataEC50:  487nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552357BDBM50552357(CHEMBL4780280)
Affinity DataEC50:  508nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552353BDBM50552353(CHEMBL4742005)
Affinity DataEC50:  591nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552331BDBM50552331(CHEMBL4795139)
Affinity DataEC50:  1.34E+3nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552344BDBM50552344(CHEMBL4748116)
Affinity DataEC50:  1.65E+3nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552335BDBM50552335(CHEMBL4752766)
Affinity DataEC50:  1.98E+3nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552330BDBM50552330(CHEMBL4745982)
Affinity DataEC50:  2.10E+3nMAssay Description:Positive allosteric modulation of mGluR5 (unknown origin) by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552333BDBM50552333(CHEMBL4760570)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552332BDBM50552332(CHEMBL4797971)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552331BDBM50552331(CHEMBL4795139)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552340BDBM50552340(CHEMBL4789952)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552339BDBM50552339(CHEMBL4744841)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552355BDBM50552355(CHEMBL4779008)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552338BDBM50552338(CHEMBL4795522)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552337BDBM50552337(CHEMBL4744409)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
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