Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50012276
TargetCasein kinase II subunit alpha'(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human CK2alpha' in presence of ATP at Km concentration by radiometric filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human CK2alpha in presence of ATP at Km concentration by radiometric filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 6nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha expressed in HEK293T permeabilized cells measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556137(CHEMBL4793819)
Affinity DataIC50: 8nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha expressed in HEK293T permeabilized cells measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556137(CHEMBL4793819)
Affinity DataKd:  12nMAssay Description:Binding affinity to N-terminal His6-tagged CK2alpha (1 to 337 residues) (unknown origin) expressed in BL21(DE3) cells by isothermal titration calorim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDeath-associated protein kinase 3(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human DAPK3 in presence of ATP at Km concentration by radiometric filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase TBK1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human TBK1 in presence of ATP at Km concentration by radiometric filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human FLT3 in presence of ATP at Km concentration by radiometric filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha'(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556137(CHEMBL4793819)
Affinity DataIC50: 38nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha' expressed in HEK293T permeabilized cells measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556138(CHEMBL4757618)
Affinity DataIC50: 40nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha expressed in HEK293T permeabilized cells measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK3(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human CLK3 in presence of ATP at Km concentration by radiometric filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHomeodomain-interacting protein kinase 3(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant human HIPK3 in presence of ATP at Km concentration by radiometric filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase pim-1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human PIM1 in presence of ATP at Km concentration by radiometric filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant human CDK1/cyclin B in presence of ATP at Km concentration by radiometric filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556142(CHEMBL4795226)
Affinity DataIC50: 75nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha expressed in HEK293T permeabilized cells measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556138(CHEMBL4757618)
Affinity DataKd:  82nMAssay Description:Binding affinity to N-terminal His6-tagged CK2alpha (1 to 337 residues) (unknown origin) expressed in BL21(DE3) cells by isothermal titration calorim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 96nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha expressed in HEK293T cells measured after 2 hrs by NanoB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha'(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 163nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha' expressed in HEK293T permeabilized cells measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha'(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556142(CHEMBL4795226)
Affinity DataIC50: 303nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha' expressed in HEK293T permeabilized cells measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha'(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 552nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha' expressed in HEK293T cells measured after 2 hrs by Nano...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha'(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556138(CHEMBL4757618)
Affinity DataIC50: 771nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha' expressed in HEK293T permeabilized cells measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556137(CHEMBL4793819)
Affinity DataIC50: 1.51E+3nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha expressed in HEK293T cells measured after 2 hrs by NanoB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556142(CHEMBL4795226)
Affinity DataIC50: 5.73E+3nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha expressed in HEK293T cells measured after 2 hrs by NanoB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha'(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556138(CHEMBL4757618)
Affinity DataIC50: 7.39E+3nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha' expressed in HEK293T cells measured after 2 hrs by Nano...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556139(CHEMBL4744728)
Affinity DataIC50: 7.52E+3nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha expressed in HEK293T permeabilized cells measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha'(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556137(CHEMBL4793819)
Affinity DataIC50: 7.64E+3nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha' expressed in HEK293T cells measured after 2 hrs by Nano...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556141(CHEMBL4778998)
Affinity DataIC50: 1.32E+4nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha expressed in HEK293T permeabilized cells measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha'(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556142(CHEMBL4795226)
Affinity DataIC50: 1.62E+4nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha' expressed in HEK293T cells measured after 2 hrs by Nano...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha'(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556139(CHEMBL4744728)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha' expressed in HEK293T cells measured after 2 hrs by Nano...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha'(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556140(CHEMBL4779625)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha' expressed in HEK293T permeabilized cells measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha'(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556139(CHEMBL4744728)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha' expressed in HEK293T permeabilized cells measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556141(CHEMBL4778998)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha expressed in HEK293T cells measured after 2 hrs by NanoB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556138(CHEMBL4757618)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha expressed in HEK293T cells measured after 2 hrs by NanoB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556140(CHEMBL4779625)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha expressed in HEK293T cells measured after 2 hrs by NanoB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556139(CHEMBL4744728)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha expressed in HEK293T cells measured after 2 hrs by NanoB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha'(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556141(CHEMBL4778998)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha' expressed in HEK293T cells measured after 2 hrs by Nano...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha'(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556140(CHEMBL4779625)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha' expressed in HEK293T cells measured after 2 hrs by Nano...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha'(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556141(CHEMBL4778998)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha' expressed in HEK293T permeabilized cells measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556140(CHEMBL4779625)
Affinity DataIC50: 7.09E+4nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha expressed in HEK293T permeabilized cells measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed