Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50018770
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM23163({2-amino-3-hydroxy-2-[2-(4-octylphenyl)ethyl]propo...)
Affinity DataEC50:  0.100nMAssay Description:Activity at human S1P3 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM23163({2-amino-3-hydroxy-2-[2-(4-octylphenyl)ethyl]propo...)
Affinity DataEC50:  1.30nMAssay Description:Activity at human S1P1 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198835([3-amino-3-(4-decylphenylcarbamoyl)-2-fluoropropyl...)
Affinity DataEC50:  2.10nMAssay Description:Activity at human S1P1 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198830((R)-3-amino-4-(4-decylphenylamino)-4-oxobutylphosp...)
Affinity DataEC50:  3.60nMAssay Description:Activity at human S1P1 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM23163({2-amino-3-hydroxy-2-[2-(4-octylphenyl)ethyl]propo...)
Affinity DataEC50:  4nMAssay Description:Activity at human S1P4 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM23163({2-amino-3-hydroxy-2-[2-(4-octylphenyl)ethyl]propo...)
Affinity DataEC50:  4nMAssay Description:Activity at human S1P5 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198835([3-amino-3-(4-decylphenylcarbamoyl)-2-fluoropropyl...)
Affinity DataEC50:  19nMAssay Description:Activity at human S1P5 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198835([3-amino-3-(4-decylphenylcarbamoyl)-2-fluoropropyl...)
Affinity DataEC50:  23nMAssay Description:Activity at human S1P3 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198834([3-amino-3-(4-octylphenylcarbamoyl)propyl]-phospho...)
Affinity DataEC50:  27nMAssay Description:Activity at human S1P1 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198830((R)-3-amino-4-(4-decylphenylamino)-4-oxobutylphosp...)
Affinity DataEC50:  30nMAssay Description:Activity at human S1P5 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198831([3-amino-4-(3-octylphenylamino)-butyl]-phosphonic ...)
Affinity DataEC50:  30nMAssay Description:Activity at human S1P1 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50133425(CHEMBL227371 | CHEMBL422074 | Phosphoric acid mono...)
Affinity DataKi:  30nMAssay Description:Displacement of [32P]S1P from human S1P1 receptor expressed in HEK293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198836([3-amino-3-(3-octylphenylcarbamoyl)propyl]-phospho...)
Affinity DataKi:  30nMAssay Description:Displacement of [32P]S1P from human S1P1 receptor expressed in HEK293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198837([3-amino-4-(4-octylphenoxy)-butyl]-phosphonic acid...)
Affinity DataEC50:  31nMAssay Description:Activity at human S1P5 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198836([3-amino-3-(3-octylphenylcarbamoyl)propyl]-phospho...)
Affinity DataEC50:  33nMAssay Description:Activity at human S1P5 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198839([3-hydroxy-4-(4-octylphenoxy)-butyl]-phosphonic ac...)
Affinity DataEC50:  33nMAssay Description:Activity at human S1P1 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198831([3-amino-4-(3-octylphenylamino)-butyl]-phosphonic ...)
Affinity DataEC50:  41nMAssay Description:Activity at human S1P5 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198830((R)-3-amino-4-(4-decylphenylamino)-4-oxobutylphosp...)
Affinity DataEC50:  43nMAssay Description:Activity at human S1P3 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198838([3-amino-4-(4-octylphenoxy)-butyl]-phosphonic acid...)
Affinity DataEC50:  47nMAssay Description:Activity at human S1P5 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198833((R)-2-amino-3-(3-octylphenylamino)-3-oxopropyl dih...)
Affinity DataEC50:  52nMAssay Description:Activity at human S1P5 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198833((R)-2-amino-3-(3-octylphenylamino)-3-oxopropyl dih...)
Affinity DataEC50:  58nMAssay Description:Activity at human S1P1 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198837([3-amino-4-(4-octylphenoxy)-butyl]-phosphonic acid...)
Affinity DataEC50:  68nMAssay Description:Activity at human S1P1 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198834([3-amino-3-(4-octylphenylcarbamoyl)propyl]-phospho...)
Affinity DataEC50:  76nMAssay Description:Activity at human S1P5 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198838([3-amino-4-(4-octylphenoxy)-butyl]-phosphonic acid...)
Affinity DataEC50:  100nMAssay Description:Activity at human S1P3 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50133425(CHEMBL227371 | CHEMBL422074 | Phosphoric acid mono...)
Affinity DataEC50:  120nMAssay Description:Activity at human S1P4 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198838([3-amino-4-(4-octylphenoxy)-butyl]-phosphonic acid...)
Affinity DataEC50:  140nMAssay Description:Activity at human S1P1 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198837([3-amino-4-(4-octylphenoxy)-butyl]-phosphonic acid...)
Affinity DataEC50:  147nMAssay Description:Activity at human S1P4 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198838([3-amino-4-(4-octylphenoxy)-butyl]-phosphonic acid...)
Affinity DataEC50:  150nMAssay Description:Activity at human S1P4 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198835([3-amino-3-(4-decylphenylcarbamoyl)-2-fluoropropyl...)
Affinity DataEC50:  170nMAssay Description:Activity at human S1P4 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198830((R)-3-amino-4-(4-decylphenylamino)-4-oxobutylphosp...)
Affinity DataEC50:  230nMAssay Description:Activity at human S1P4 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198834([3-amino-3-(4-octylphenylcarbamoyl)propyl]-phospho...)
Affinity DataEC50:  270nMAssay Description:Activity at human S1P3 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198830((R)-3-amino-4-(4-decylphenylamino)-4-oxobutylphosp...)
Affinity DataEC50:  270nMAssay Description:Activity at human S1P2 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198836([3-amino-3-(3-octylphenylcarbamoyl)propyl]-phospho...)
Affinity DataKi:  300nMAssay Description:Displacement of [32P]S1P from human S1P3 receptor expressed in HEK293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50133425(CHEMBL227371 | CHEMBL422074 | Phosphoric acid mono...)
Affinity DataKi:  300nMAssay Description:Displacement of [32P]S1P from human S1P3 receptor expressed in HEK293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198831([3-amino-4-(3-octylphenylamino)-butyl]-phosphonic ...)
Affinity DataEC50:  340nMAssay Description:Activity at human S1P4 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198833((R)-2-amino-3-(3-octylphenylamino)-3-oxopropyl dih...)
Affinity DataEC50:  450nMAssay Description:Activity at human S1P3 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50133425(CHEMBL227371 | CHEMBL422074 | Phosphoric acid mono...)
Affinity DataEC50:  480nMAssay Description:Activity at human S1P5 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198835([3-amino-3-(4-decylphenylcarbamoyl)-2-fluoropropyl...)
Affinity DataEC50:  490nMAssay Description:Activity at human S1P2 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198833((R)-2-amino-3-(3-octylphenylamino)-3-oxopropyl dih...)
Affinity DataEC50:  500nMAssay Description:Activity at human S1P4 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198838([3-amino-4-(4-octylphenoxy)-butyl]-phosphonic acid...)
Affinity DataEC50:  530nMAssay Description:Activity at human S1P2 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198832([3-amino-3-(4-octylphenylcarbamoyl)propyl]-phospho...)
Affinity DataEC50:  1.20E+3nMAssay Description:Activity at human S1P1 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198834([3-amino-3-(4-octylphenylcarbamoyl)propyl]-phospho...)
Affinity DataEC50:  2.30E+3nMAssay Description:Activity at human S1P4 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198836([3-amino-3-(3-octylphenylcarbamoyl)propyl]-phospho...)
Affinity DataEC50:  6.10E+3nMAssay Description:Activity at human S1P4 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198832([3-amino-3-(4-octylphenylcarbamoyl)propyl]-phospho...)
Affinity DataEC50:  1.50E+4nMAssay Description:Activity at human S1P3 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50198839([3-hydroxy-4-(4-octylphenoxy)-butyl]-phosphonic ac...)
Affinity DataEC50:  4.40E+5nMAssay Description:Activity at human S1P4 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed