Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50026225
TargetCannabinoid receptor 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067499BDBM50067499((6aR,10aR)-3-(1,1-dimethyl-heptyl)-9-hydroxymethyl...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]CP-55940 form human recombinant CB1 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266832BDBM50266832(1-(2,4-Dichlorophenyl)-4-cyano-5-(4-methoxyphenyl)...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]CP-55940 form human recombinant CB1 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50267374BDBM50267374(1-(2-bromophenyl)-4-cyano-5-(4-methoxyphenyl)-N-(p...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]CP-55940 form human recombinant CB1 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266833BDBM50266833(1-(2,4-Dichlorophenyl)-4-cyano-5-(4-(fluoromethoxy...)
Affinity DataKi:  10.3nMAssay Description:Displacement of [3H]CP-55940 form human recombinant CB1 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50267373BDBM50267373(4-cyano-1-(2,4-dichlorophenyl)-5-(4-methoxyphenyl)...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]CP-55940 form human recombinant CB1 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50267375BDBM50267375(1-(2-Chloro-4-fluorophenyl)-4-cyano-5-(4-methoxyph...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]CP-55940 form human recombinant CB1 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266809BDBM50266809(1-(2,4-Dichlorophenyl)-4-cyano-5-(4-bromophenyl)-N...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]CP-55940 form human recombinant CB1 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266864BDBM50266864(5-(4-chlorophenyl)-4-cyano-1-(2,4-dichlorophenyl)-...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]CP-55940 form human recombinant CB1 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266807BDBM50266807(1-(2-Bromo-4-fluorophenyl)-4-cyano-5-(4-methoxyphe...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]CP-55940 form human recombinant CB1 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266808BDBM50266808(1-(2,4-Dichlorophenyl)-4-cyano-5-(4-iodophenyl)-N-...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]CP-55940 form human recombinant CB1 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21278BDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]CP-55940 form human recombinant CB1 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266830BDBM50266830(1-(2,4-Dichlorophenyl)-4-cyano-5-(4-iodophenyl)-N-...)
Affinity DataKi:  131nMAssay Description:Displacement of [3H]CP-55940 form human recombinant CB1 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50267372BDBM50267372(AM-281 | 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4...)
Affinity DataKi:  422nMAssay Description:Displacement of [3H]CP-55940 form human recombinant CB1 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266831BDBM50266831(1-(2,4-Dichlorophenyl)-4-cyano-5-(4-bromophenyl)-N...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CP-55940 form human recombinant CB1 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266810BDBM50266810(1-(2-Bromophenyl)-5-(4-methoxyphenyl)-N3-(piperidi...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP-55940 form human recombinant CB1 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed