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Found 18 Enz. Inhib. hit(s) with all data for entry = 50029004
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50280660(CHEMBL11891 | Sodium; (E)-(3R,5S)-9,9-bis-(4-fluor...)
Affinity DataIC50:  20nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase from rat hepatocyteMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50014345(CHEMBL11804 | Sodium; (E)-(3R,5S)-9,9-bis-(4-fluor...)
Affinity DataIC50:  21nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase in liver cell preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50014345(CHEMBL11804 | Sodium; (E)-(3R,5S)-9,9-bis-(4-fluor...)
Affinity DataIC50:  21nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50004774((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)
Affinity DataIC50:  27nMAssay Description:Compound was evaluated in vitro for inhibitory activity against isolated enzyme HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50004774((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)
Affinity DataIC50:  32nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase from rat hepatocyteMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50004774((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)
Affinity DataIC50:  39nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50014345(CHEMBL11804 | Sodium; (E)-(3R,5S)-9,9-bis-(4-fluor...)
Affinity DataIC50:  43nMAssay Description:Compound was evaluated in vitro for inhibitory activity against isolated enzyme HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50280661(CHEMBL276717 | Sodium; (E)-(3R,5S)-9,9-bis-(4-fluo...)
Affinity DataIC50:  100nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase from rat hepatocyteMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280660(CHEMBL11891 | Sodium; (E)-(3R,5S)-9,9-bis-(4-fluor...)
Affinity DataIC50:  120nMAssay Description:Compound was evaluated in vitro for inhibitory activity against isolated enzyme HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280661(CHEMBL276717 | Sodium; (E)-(3R,5S)-9,9-bis-(4-fluo...)
Affinity DataIC50:  630nMAssay Description:Compound was evaluated in vitro for inhibitory activity against isolated enzyme HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280661(CHEMBL276717 | Sodium; (E)-(3R,5S)-9,9-bis-(4-fluo...)
Affinity DataIC50:  1.29E+3nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50014345(CHEMBL11804 | Sodium; (E)-(3R,5S)-9,9-bis-(4-fluor...)
Affinity DataIC50:  1.34E+3nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase in testes cell preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50014345(CHEMBL11804 | Sodium; (E)-(3R,5S)-9,9-bis-(4-fluor...)
Affinity DataIC50:  1.60E+3nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase in adrenal cell preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280660(CHEMBL11891 | Sodium; (E)-(3R,5S)-9,9-bis-(4-fluor...)
Affinity DataIC50:  1.72E+3nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50014345(CHEMBL11804 | Sodium; (E)-(3R,5S)-9,9-bis-(4-fluor...)
Affinity DataIC50:  1.80E+3nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase in bovine occular cell preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50014345(CHEMBL11804 | Sodium; (E)-(3R,5S)-9,9-bis-(4-fluor...)
Affinity DataIC50:  3.00E+3nMAssay Description:Compound was evaluated for inhibitory activity against rat hepatocyteMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50014345(CHEMBL11804 | Sodium; (E)-(3R,5S)-9,9-bis-(4-fluor...)
Affinity DataIC50:  3.20E+3nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase in spleen cell preparationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280662(CHEMBL268767 | Sodium; (E)-(3R,5S)-9,9-bis-(4-fluo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated in vitro for inhibitory activity against isolated enzyme HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article