Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50029130
TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281657(cis-4-[({1-[(2S)-2-carboxy-3-(2-methoxyethoxy)prop...)
Affinity DataIC50: 38nMAssay Description:The compound was tested for its inhibitory activity against neutral endopeptidase (EC.3.4.24.111) in rat kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM21641(2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...)
Affinity DataIC50: 40nMAssay Description:The compound was tested for its inhibitory activity against neutral endopeptidase (EC.3.4.24.111) in rat kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281655((1S,3R)-3-(2-Mercaptomethyl-3-phenyl-propionylamin...)
Affinity DataIC50: 180nMAssay Description:The compound was tested for its inhibitory activity against neutral endopeptidase (EC.3.4.24.111) in rat kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281654((1S,3R)-3-[(1-Mercaptomethyl-cyclopentanecarbonyl)...)
Affinity DataIC50: 215nMAssay Description:The compound was tested for its inhibitory activity against neutral endopeptidase (EC.3.4.24.111) in rat kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281653((S)-2-[(1-Mercaptomethyl-cyclopentanecarbonyl)-ami...)
Affinity DataIC50: 220nMAssay Description:The compound was tested for its inhibitory activity against neutral endopeptidase (EC.3.4.24.111) in rat kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281656(x(1S,3R)-3-[(1-Mercaptomethyl-cyclopentanecarbonyl...)
Affinity DataIC50: 310nMAssay Description:The compound was tested for its inhibitory activity against neutral endopeptidase (EC.3.4.24.111) in rat kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article