Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50029624
TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450390BDBM50450390(CHEMBL99056)
Affinity DataIC50: 80nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450384BDBM50450384(CHEMBL317244)
Affinity DataIC50: 80nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286270BDBM50286270(N-[(2-Dodecyl-2H-tetrazol-5-yl)-phenyl-methyl]-2,6...)
Affinity DataIC50: 110nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in intestinal microsomes isolated from chole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005944BDBM50005944(2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...)
Affinity DataIC50: 110nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450382BDBM50450382(CHEMBL101629)
Affinity DataIC50: 120nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450380BDBM50450380(CHEMBL100936)
Affinity DataIC50: 140nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450389BDBM50450389(CHEMBL318373)
Affinity DataIC50: 180nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450386BDBM50450386(CHEMBL98716)
Affinity DataIC50: 190nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450394BDBM50450394(CHEMBL101601)
Affinity DataIC50: 240nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450392BDBM50450392(CHEMBL101883)
Affinity DataIC50: 250nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286270BDBM50286270(N-[(2-Dodecyl-2H-tetrazol-5-yl)-phenyl-methyl]-2,6...)
Affinity DataIC50: 310nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450373BDBM50450373(CHEMBL98742)
Affinity DataIC50: 350nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450393BDBM50450393(CHEMBL101278)
Affinity DataIC50: 350nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450378BDBM50450378(CHEMBL99029)
Affinity DataIC50: 380nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450372BDBM50450372(CHEMBL316471)
Affinity DataIC50: 380nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450381BDBM50450381(CHEMBL97926)
Affinity DataIC50: 440nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286284BDBM50286284(2,6-Dimethyl-N-[(2-pentadecyl-2H-tetrazol-5-yl)-ph...)
Affinity DataIC50: 440nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in intestinal microsomes isolated from chole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450387BDBM50450387(CHEMBL100993)
Affinity DataIC50: 460nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450379BDBM50450379(CHEMBL101937)
Affinity DataIC50: 490nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450377BDBM50450377(CHEMBL100533)
Affinity DataIC50: 510nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450385BDBM50450385(CHEMBL98598)
Affinity DataIC50: 540nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450376BDBM50450376(CHEMBL101865)
Affinity DataIC50: 600nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450375BDBM50450375(CHEMBL101977)
Affinity DataIC50: 650nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450388BDBM50450388(CHEMBL321102)
Affinity DataIC50: 810nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450383BDBM50450383(CHEMBL98365)
Affinity DataIC50: 850nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450391BDBM50450391(CHEMBL98612)
Affinity DataIC50: 1.70E+3nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286287BDBM50286287(N-[(2-Heptyl-2H-tetrazol-5-yl)-phenyl-methyl]-2,6-...)
Affinity DataIC50: 3.70E+3nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in intestinal microsomes isolated from chole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047604BDBM50047604(2,4,6-Trimethoxy-N-octadec-9-enyl-benzamide | CHEM...)
Affinity DataIC50: 9.40E+3nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450374BDBM50450374(CHEMBL317503)
Affinity DataIC50: 1.00E+4nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article