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Found 23 Enz. Inhib. hit(s) with all data for entry = 50029679
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286755(8-Methoxy-5,10-dihydro-3H-pyrimido[4,5-b]quinolin-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of cellular oncogene pp60 c-srcMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50132155(7,8-Dimethoxy-5,10-dihydro-1H-pyrimido[4,5-b]quino...)
Affinity DataIC50:  500nMAssay Description:Inhibition of cellular oncogene pp60 c-srcMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286752(7,8-Dimethoxy-3-methyl-5,10-dihydro-3H-pyrimido[4,...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of cellular oncogene pp60 c-srcMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286758(7-Methoxy-5,10-dihydro-3H-pyrimido[4,5-b]quinolin-...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of cellular oncogene pp60 c-srcMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286753(5,10-Dihydro-3H-pyrimido[4,5-b]quinolin-4-one | CH...)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of cellular oncogene pp60 c-srcMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50132157(7,8-Dimethoxy-1H-pyrimido[4,5-b]quinolin-4-one | 7...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of cellular oncogene pp60 c-srcMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286759(2-Ethyl-5,10-dihydro-3H-pyrimido[4,5-b]quinolin-4-...)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of cellular oncogene pp60 c-srcMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50132155(7,8-Dimethoxy-5,10-dihydro-1H-pyrimido[4,5-b]quino...)
Affinity DataIC50:  7.50E+4nMAssay Description:Inhibition of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286757(7,8-Dimethoxy-3-(2-morpholin-4-yl-ethyl)-5,10-dihy...)
Affinity DataIC50:  1.05E+5nMAssay Description:Inhibition of cellular oncogene pp60 c-srcMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286752(7,8-Dimethoxy-3-methyl-5,10-dihydro-3H-pyrimido[4,...)
Affinity DataIC50:  1.60E+5nMAssay Description:Inhibition of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286751(3,9-Dihydro-pyrimido[4,5-b]indol-4-one | CHEMBL267...)
Affinity DataIC50:  2.93E+5nMAssay Description:Inhibition of cellular oncogene pp60 c-srcMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286754(10-Ethyl-5,10-dihydro-3H-pyrimido[4,5-b]quinolin-4...)
Affinity DataIC50:  5.50E+5nMAssay Description:Inhibition of cellular oncogene pp60 c-srcMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50132157(7,8-Dimethoxy-1H-pyrimido[4,5-b]quinolin-4-one | 7...)
Affinity DataIC50: >7.50E+5nMAssay Description:Inhibition of cAMP-dependent kinase (Protein kinase A)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50286754(10-Ethyl-5,10-dihydro-3H-pyrimido[4,5-b]quinolin-4...)
Affinity DataIC50: >9.60E+5nMAssay Description:Inhibition of cAMP-dependent kinase (Protein kinase A)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50286757(7,8-Dimethoxy-3-(2-morpholin-4-yl-ethyl)-5,10-dihy...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of cAMP-dependent kinase (Protein kinase A)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286756(6-Phenylamino-3H-pyrimidin-4-one | CHEMBL7052)
Affinity DataIC50:  1.55E+6nMAssay Description:Inhibition of cellular oncogene pp60 c-srcMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50286759(2-Ethyl-5,10-dihydro-3H-pyrimido[4,5-b]quinolin-4-...)
Affinity DataIC50: >3.00E+6nMAssay Description:Inhibition of cAMP-dependent kinase (Protein kinase A)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50286755(8-Methoxy-5,10-dihydro-3H-pyrimido[4,5-b]quinolin-...)
Affinity DataIC50: >3.00E+6nMAssay Description:Inhibition of cAMP-dependent kinase (Protein kinase A)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50132155(7,8-Dimethoxy-5,10-dihydro-1H-pyrimido[4,5-b]quino...)
Affinity DataIC50: >3.00E+6nMAssay Description:Inhibition of cAMP-dependent kinase (Protein kinase A)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50286752(7,8-Dimethoxy-3-methyl-5,10-dihydro-3H-pyrimido[4,...)
Affinity DataIC50: >3.00E+6nMAssay Description:Inhibition of cAMP-dependent kinase (Protein kinase A)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50286753(5,10-Dihydro-3H-pyrimido[4,5-b]quinolin-4-one | CH...)
Affinity DataIC50: >3.00E+6nMAssay Description:Inhibition of cAMP-dependent kinase (Protein kinase A)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50286758(7-Methoxy-5,10-dihydro-3H-pyrimido[4,5-b]quinolin-...)
Affinity DataIC50: >3.00E+6nMAssay Description:Inhibition of cAMP-dependent kinase (Protein kinase A)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50286756(6-Phenylamino-3H-pyrimidin-4-one | CHEMBL7052)
Affinity DataIC50: >4.00E+6nMAssay Description:Inhibition of cAMP-dependent kinase (Protein kinase A)More data for this Ligand-Target Pair
In DepthDetails Article