Compile Data Set for Download or QSAR
maximum 50k data
Found 57 Enz. Inhib. hit(s) with all data for entry = 50029715
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287200(1-Benzo[1,3]dioxol-5-ylmethyl-5,6-dimethoxy-3-(3,4...)
Affinity DataIC50:  2nMAssay Description:Affinity for human endothelin A receptor expressed in Ltk cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287200(1-Benzo[1,3]dioxol-5-ylmethyl-5,6-dimethoxy-3-(3,4...)
Affinity DataIC50:  4.60nMAssay Description:Affinity for human endothelin A receptor expressed in Ltk cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287183(1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-...)
Affinity DataIC50:  5nMAssay Description:Affinity for human endothelin A receptor expressed in Ltk cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287190(5-Benzo[1,3]dioxol-5-ylmethyl-7-(3,4,5-trimethoxy-...)
Affinity DataIC50:  7nMAssay Description:Affinity for human endothelin A receptor expressed in Ltk cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287186(1-Benzo[1,3]dioxol-5-ylmethyl-5,6-dimethoxy-3-(3-m...)
Affinity DataIC50:  20nMAssay Description:Affinity for human endothelin A receptor expressed in Ltk cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287186(1-Benzo[1,3]dioxol-5-ylmethyl-5,6-dimethoxy-3-(3-m...)
Affinity DataIC50:  33nMAssay Description:Affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287196(5-Benzo[1,3]dioxol-5-ylmethyl-7-(3,4-dimethoxy-phe...)
Affinity DataIC50:  41nMAssay Description:Affinity for human endothelin A receptor expressed in Ltk cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287194(5,6-Dimethoxy-1-(7-methoxy-benzo[1,3]dioxol-5-ylme...)
Affinity DataIC50:  58nMAssay Description:Affinity for human endothelin A receptor expressed in Ltk cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287190(5-Benzo[1,3]dioxol-5-ylmethyl-7-(3,4,5-trimethoxy-...)
Affinity DataIC50:  64nMAssay Description:Affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287196(5-Benzo[1,3]dioxol-5-ylmethyl-7-(3,4-dimethoxy-phe...)
Affinity DataIC50:  65nMAssay Description:Inhibition of ET- 1 stimulated arachidonic acid release (AAR) in cultured rabbit renal vascular smooth muscle cells expressing the endothelin A recep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287185(1-Benzo[1,3]dioxol-5-ylmethyl-5-benzyloxy-6-methox...)
Affinity DataIC50:  81nMAssay Description:Affinity for human endothelin A receptor expressed in Ltk cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287182(5-Benzo[1,3]dioxol-5-ylmethyl-7-(3-methoxy-phenyls...)
Affinity DataIC50:  84nMAssay Description:Affinity for human endothelin A receptor expressed in Ltk cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287198(1-Benzo[1,3]dioxol-5-ylmethyl-3-(3-methoxy-phenyls...)
Affinity DataIC50:  86nMAssay Description:Affinity for human endothelin A receptor expressed in Ltk cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287202(5-Benzo[1,3]dioxol-5-ylmethyl-7-(benzo[1,3]dioxol-...)
Affinity DataIC50:  100nMAssay Description:Affinity for human endothelin A receptor expressed in Ltk cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287183(1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of ET- 1 stimulated arachidonic acid release (AAR) in cultured rabbit renal vascular smooth muscle cells expressing the endothelin A recep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287199(1-Benzyl-5,6-dimethoxy-3-(3-methoxy-phenylsulfanyl...)
Affinity DataIC50:  160nMAssay Description:Affinity for human endothelin A receptor expressed in Ltk cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287196(5-Benzo[1,3]dioxol-5-ylmethyl-7-(3,4-dimethoxy-phe...)
Affinity DataIC50:  170nMAssay Description:Inhibition of ET- 1 stimulated arachidonic acid release (AAR) in cultured rabbit renal vascular smooth muscle cells expressing the endothelin B recep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287196(5-Benzo[1,3]dioxol-5-ylmethyl-7-(3,4-dimethoxy-phe...)
Affinity DataIC50:  170nMAssay Description:Inhibition of sarafotoxin-6c stimulated vasoconstriction in rabbit pulmonary artery.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287191(7-(3,4-Dimethoxy-phenylsulfanyl)-5-(7-methoxy-benz...)
Affinity DataIC50:  170nMAssay Description:Affinity for human endothelin A receptor expressed in Ltk cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287190(5-Benzo[1,3]dioxol-5-ylmethyl-7-(3,4,5-trimethoxy-...)
Affinity DataIC50:  170nMAssay Description:Inhibition of ET- 1 stimulated arachidonic acid release (AAR) in cultured rabbit renal vascular smooth muscle cells expressing the endothelin B recep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287190(5-Benzo[1,3]dioxol-5-ylmethyl-7-(3,4,5-trimethoxy-...)
Affinity DataIC50:  230nMAssay Description:Inhibition of sarafotoxin-6c stimulated vasoconstriction in rabbit pulmonary artery.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287183(1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-...)
Affinity DataIC50:  280nMAssay Description:Inhibition of ET- 1 stimulated arachidonic acid release (AAR) in cultured rabbit renal vascular smooth muscle cells expressing the endothelin A recep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287200(1-Benzo[1,3]dioxol-5-ylmethyl-5,6-dimethoxy-3-(3,4...)
Affinity DataIC50:  380nMAssay Description:Affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287201(5-(7-Methoxy-benzo[1,3]dioxol-5-ylmethyl)-7-(3-met...)
Affinity DataIC50:  380nMAssay Description:Affinity for human endothelin A receptor expressed in Ltk cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287195(1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-...)
Affinity DataIC50:  380nMAssay Description:Affinity for human endothelin A receptor expressed in Ltk cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287191(7-(3,4-Dimethoxy-phenylsulfanyl)-5-(7-methoxy-benz...)
Affinity DataIC50:  420nMAssay Description:Affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287202(5-Benzo[1,3]dioxol-5-ylmethyl-7-(benzo[1,3]dioxol-...)
Affinity DataIC50:  420nMAssay Description:Affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287200(1-Benzo[1,3]dioxol-5-ylmethyl-5,6-dimethoxy-3-(3,4...)
Affinity DataIC50:  440nMAssay Description:Affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287197(1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-...)
Affinity DataIC50:  490nMAssay Description:Inhibition of ET- 1 stimulated arachidonic acid release (AAR) in cultured rabbit renal vascular smooth muscle cells expressing the endothelin A recep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287192(1-Benzo[1,3]dioxol-5-ylmethyl-3-(3-methoxy-phenyls...)
Affinity DataIC50:  590nMAssay Description:Affinity for human endothelin A receptor expressed in Ltk cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287197(1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-...)
Affinity DataIC50:  620nMAssay Description:Affinity for human endothelin A receptor expressed in Ltk cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287185(1-Benzo[1,3]dioxol-5-ylmethyl-5-benzyloxy-6-methox...)
Affinity DataIC50:  690nMAssay Description:Affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287197(1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-...)
Affinity DataIC50:  740nMAssay Description:Inhibition of ET- 1 stimulated arachidonic acid release (AAR) in cultured rabbit renal vascular smooth muscle cells expressing the endothelin B recep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287182(5-Benzo[1,3]dioxol-5-ylmethyl-7-(3-methoxy-phenyls...)
Affinity DataIC50:  760nMAssay Description:Affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287199(1-Benzyl-5,6-dimethoxy-3-(3-methoxy-phenylsulfanyl...)
Affinity DataIC50:  870nMAssay Description:Affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287186(1-Benzo[1,3]dioxol-5-ylmethyl-5,6-dimethoxy-3-(3-m...)
Affinity DataIC50:  1.10E+3nMAssay Description:Affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287194(5,6-Dimethoxy-1-(7-methoxy-benzo[1,3]dioxol-5-ylme...)
Affinity DataIC50:  1.10E+3nMAssay Description:Affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287186(1-Benzo[1,3]dioxol-5-ylmethyl-5,6-dimethoxy-3-(3-m...)
Affinity DataIC50:  1.10E+3nMAssay Description:Affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287183(1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of ET- 1 stimulated arachidonic acid release (AAR) in cultured rabbit renal vascular smooth muscle cells expressing the endothelin B recep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287181(1-Benzo[1,3]dioxol-5-ylmethyl-6-benzyloxy-5-methox...)
Affinity DataIC50:  1.60E+3nMAssay Description:Affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287193(1-Benzo[1,3]dioxol-5-ylmethyl-6-benzyloxy-5-methox...)
Affinity DataIC50: >2.50E+3nMAssay Description:Affinity for human endothelin A receptor expressed in Ltk cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287193(1-Benzo[1,3]dioxol-5-ylmethyl-6-benzyloxy-5-methox...)
Affinity DataIC50: >2.50E+3nMAssay Description:Affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287197(1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of ET- 1 stimulated arachidonic acid release (AAR) in cultured rabbit renal vascular smooth muscle cells expressing the endothelin A recep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287195(1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-...)
Affinity DataIC50:  4.50E+3nMAssay Description:Affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287189(1-Benzyl-3-(3-methoxy-phenylsulfanyl)-1H-indole-2-...)
Affinity DataIC50:  4.60E+3nMAssay Description:Affinity for human endothelin A receptor expressed in Ltk cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287188(3-(3-Methoxy-phenylsulfanyl)-benzo[b]thiophene-2-c...)
Affinity DataIC50:  5.90E+3nMAssay Description:Compound was evaluated for the receptor binding activity in rabbit artery vascular smooth muscle cells expressing Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287187(5-Benzyloxy-3-isopropoxy-benzo[b]thiophene-2-carbo...)
Affinity DataIC50:  6.00E+3nMAssay Description:Compound was evaluated for the receptor binding activity in rabbit artery vascular smooth muscle cells expressing Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287192(1-Benzo[1,3]dioxol-5-ylmethyl-3-(3-methoxy-phenyls...)
Affinity DataIC50:  6.70E+3nMAssay Description:Affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287198(1-Benzo[1,3]dioxol-5-ylmethyl-3-(3-methoxy-phenyls...)
Affinity DataIC50:  7.40E+3nMAssay Description:Affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287187(5-Benzyloxy-3-isopropoxy-benzo[b]thiophene-2-carbo...)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of sarafotoxin-6c stimulated vasoconstriction in rabbit pulmonary artery.More data for this Ligand-Target Pair
In DepthDetails Article
Displayed 1 to 50 (of 57 total ) | Next | Last >>
Jump to: