Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50032444
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329367BDBM50329367(2-(3-cyanobenzamido)-N-isopropyl-3-(3-methoxypropy...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329364BDBM50329364(2-(3-cyanobenzamido)-N,N-diethyl-1-(3-methoxypropy...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329367BDBM50329367(2-(3-cyanobenzamido)-N-isopropyl-3-(3-methoxypropy...)
Affinity DataKi:  4.30nMAssay Description:Antagonist activity at rat A2A receptor by cAMP functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329348BDBM50329348((R)-3-cyano-N-(3-(3-methoxypropyl)-6-(2-methylpipe...)
Affinity DataKi:  6.40nMAssay Description:Antagonist activity at rat A2A receptor by cAMP functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329348BDBM50329348((R)-3-cyano-N-(3-(3-methoxypropyl)-6-(2-methylpipe...)
Affinity DataKi:  7.70nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329342BDBM50329342(3-cyano-N-(3-(3-methoxypropyl)-6-(piperidine-1-car...)
Affinity DataKi:  9.60nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329349BDBM50329349((S)-3-cyano-N-(3-(3-methoxypropyl)-6-(2-methylpipe...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329366BDBM50329366(2-(3-cyanobenzamido)-N-ethyl-3-(3-methoxypropyl)-N...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329347BDBM50329347(2-(3-cyanobenzamido)-N-isopropyl-3-(3-methoxypropy...)
Affinity DataKi:  12nMAssay Description:Antagonist activity at rat A2A receptor by cAMP functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329347BDBM50329347(2-(3-cyanobenzamido)-N-isopropyl-3-(3-methoxypropy...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329349BDBM50329349((S)-3-cyano-N-(3-(3-methoxypropyl)-6-(2-methylpipe...)
Affinity DataKi:  14nMAssay Description:Antagonist activity at rat A2A receptor by cAMP functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329364BDBM50329364(2-(3-cyanobenzamido)-N,N-diethyl-1-(3-methoxypropy...)
Affinity DataKi:  16nMAssay Description:Antagonist activity at rat A2A receptor by cAMP functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329346BDBM50329346(2-(3-cyanobenzamido)-N,N-diethyl-3-(3-methoxypropy...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329365BDBM50329365(3-cyano-N-(1-(3-methoxypropyl)-6-(piperidine-1-car...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329366BDBM50329366(2-(3-cyanobenzamido)-N-ethyl-3-(3-methoxypropyl)-N...)
Affinity DataKi:  23nMAssay Description:Antagonist activity at rat A2A receptor by cAMP functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329345BDBM50329345(2-(3-cyanobenzamido)-N-ethyl-3-(3-methoxypropyl)-N...)
Affinity DataKi:  24nMAssay Description:Antagonist activity at rat A2A receptor by cAMP functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329345BDBM50329345(2-(3-cyanobenzamido)-N-ethyl-3-(3-methoxypropyl)-N...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329359BDBM50329359(3-cyano-N-(6-(piperidine-1-carbonyl)-3-(pyridin-4-...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329354BDBM50329354(N-(3-(2-acetamidoethyl)-6-(piperidine-1-carbonyl)-...)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329340BDBM50329340(N-butyl-2-(3-cyanobenzamido)-3-(3-methoxypropyl)-3...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329331BDBM50329331(2-(3-cyanobenzamido)-N-(3-methoxybenzyl)-1-(3-meth...)
Affinity DataKi:  46nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329339BDBM50329339(N-butyl-2-(3-cyanobenzamido)-1-(3-methoxypropyl)-1...)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329341BDBM50329341(3-cyano-N-(1-(3-methoxypropyl)-5-(piperidine-1-car...)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329352BDBM50329352(3-cyano-N-(3-(3-hydroxypropyl)-6-(piperidine-1-car...)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329346BDBM50329346(2-(3-cyanobenzamido)-N,N-diethyl-3-(3-methoxypropy...)
Affinity DataKi:  59nMAssay Description:Antagonist activity at rat A2A receptor by cAMP functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329365BDBM50329365(3-cyano-N-(1-(3-methoxypropyl)-6-(piperidine-1-car...)
Affinity DataKi:  85nMAssay Description:Antagonist activity at rat A2A receptor by cAMP functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329360BDBM50329360(3-cyano-N-(3-(3-methoxypropyl)-6-(morpholine-4-car...)
Affinity DataKi:  92nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329344BDBM50329344(2-(3-cyanobenzamido)-3-(3-methoxypropyl)-N,N-dimet...)
Affinity DataKi:  123nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329350BDBM50329350(3-cyano-N-(3-methyl-6-(piperidine-1-carbonyl)-3H-i...)
Affinity DataKi:  147nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329353BDBM50329353(3-cyano-N-(6-(piperidine-1-carbonyl)-3-(tetrahydro...)
Affinity DataKi:  179nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329333BDBM50329333(2-(3-fluorobenzamido)-N-(3-methoxybenzyl)-1-(3-met...)
Affinity DataKi:  210nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329358BDBM50329358(3-cyano-N-(6-(piperidine-1-carbonyl)-3-(pyridin-3-...)
Affinity DataKi:  233nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329355BDBM50329355(3-cyano-N-(3-(3-methoxyphenyl)-6-(piperidine-1-car...)
Affinity DataKi:  325nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329334BDBM50329334(2-(3-chlorobenzamido)-N-(3-methoxybenzyl)-1-(3-met...)
Affinity DataKi:  439nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329351BDBM50329351(3-cyano-N-(3-pentyl-6-(piperidine-1-carbonyl)-3H-i...)
Affinity DataKi:  904nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329362BDBM50329362(3-cyano-N-(3-(3-ethoxypropyl)-6-(morpholine-4-carb...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329356BDBM50329356(3-cyano-N-(3-(4-methoxybenzyl)-6-(piperidine-1-car...)
Affinity DataKi:  1.22E+3nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329338BDBM50329338(2-(4-cyanobenzamido)-N-(3-methoxybenzyl)-1-(3-meth...)
Affinity DataKi:  1.67E+3nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329336BDBM50329336(2-(3-methoxybenzamido)-N-(3-methoxybenzyl)-1-(3-me...)
Affinity DataKi:  2.38E+3nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329343BDBM50329343(2-(3-cyanobenzamido)-3-(3-methoxypropyl)-3H-imidaz...)
Affinity DataKi:  2.43E+3nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329357BDBM50329357(3-cyano-N-(3-(4-fluorobenzyl)-6-(piperidine-1-carb...)
Affinity DataKi:  2.59E+3nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329361BDBM50329361(3-cyano-N-(3-(2-ethoxyethyl)-6-(morpholine-4-carbo...)
Affinity DataKi:  3.30E+3nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329337BDBM50329337(2-(2-chlorobenzamido)-N-(3-methoxybenzyl)-1-(3-met...)
Affinity DataKi:  4.71E+3nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329332BDBM50329332(2-amino-N-(3-methoxybenzyl)-1-(3-methoxypropyl)-1H...)
Affinity DataKi:  6.77E+3nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329335BDBM50329335(N-(3-methoxybenzyl)-1-(3-methoxypropyl)-2-(3-(trif...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329363BDBM50329363(3-cyano-N-(3-(3-isopropoxypropyl)-6-(morpholine-4-...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH58261 from human recombinant A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed