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Found 8 Enz. Inhib. hit(s) with all data for entry = 50034808
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM22416((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)
Affinity DataKi:  0.0770nMAssay Description:Evaluated for affinity at 5-HT uptake site using [3H]paroxetine as radioligand in radioligand binding assayMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)
Affinity DataKi:  3.17nMAssay Description:Evaluated for affinity at 5-HT uptake site using [3H]paroxetine as radioligand in radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticleDrugBank

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50057128((2-Benzofuran-6-yl-ethyl)-((R)-5-methoxy-1,2,3,4-t...)
Affinity DataKi:  3.77nMAssay Description:Evaluated for affinity at 5-HT uptake site using [3H]paroxetine as radioligand in radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50057128((2-Benzofuran-6-yl-ethyl)-((R)-5-methoxy-1,2,3,4-t...)
Affinity DataKi:  52nMAssay Description:Compound was evaluated for its binding affinity to Dopamine receptor D2 in rat brain using [3H]- spiroperidol radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285279((2-Benzofuran-6-yl-ethyl)-((S)-5-methoxy-1,2,3,4-t...)
Affinity DataKi:  92nMAssay Description:Evaluated for affinity at 5-HT uptake site using [3H]paroxetine as radioligand in radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(1A) dopamine receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50057128((2-Benzofuran-6-yl-ethyl)-((R)-5-methoxy-1,2,3,4-t...)
Affinity DataKi:  744nMAssay Description:Compound was evaluated for its binding affinity to Dopamine receptor D1 in rat striatum using [3H]- SCH-23390 radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50057128((2-Benzofuran-6-yl-ethyl)-((R)-5-methoxy-1,2,3,4-t...)
Affinity DataKi:  836nMAssay Description:Compound was evaluated for its binding affinity to beta-1 receptor in rat brain using [3H]- DHA radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-2 adrenergic receptor(Canis familiaris)
TBA

Curated by ChEMBL
LigandPNGBDBM50057128((2-Benzofuran-6-yl-ethyl)-((R)-5-methoxy-1,2,3,4-t...)
Affinity DataKi:  1.74E+3nMAssay Description:Compound was evaluated for its binding affinity to beta-2 receptor in rat brain using [3H]- DHA radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article