Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50034840
TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287299BDBM50287299((2S,4S)-5-Biphenyl-4-yl-4-(4-carboxymethyl-thiazol...)
Affinity DataIC50: 0.690nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286906BDBM50286906((2S,4S)-5-Biphenyl-4-yl-4-(carboxymethyl-carbamoyl...)
Affinity DataIC50: 3.20nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287301BDBM50287301((2R,4S)-5-Biphenyl-4-yl-4-(4-carboxymethyl-thiazol...)
Affinity DataIC50: 3.30nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286908BDBM50286908((2R,4S)-5-Biphenyl-4-yl-4-(carboxymethyl-carbamoyl...)
Affinity DataIC50: 5.90nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287304BDBM50287304((S)-5-Biphenyl-4-yl-2-phenoxymethyl-4-(1H-tetrazol...)
Affinity DataIC50: 7.40nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21641BDBM21641(2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...)
Affinity DataIC50: 7.90nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article
PDB3D3D Structure (crystal)
TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287300BDBM50287300(2-[(S)-3-Biphenyl-4-yl-2-(4-carboxymethyl-thiazol-...)
Affinity DataIC50: 9.80nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287300BDBM50287300(2-[(S)-3-Biphenyl-4-yl-2-(4-carboxymethyl-thiazol-...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287297BDBM50287297((S)-5-Biphenyl-4-yl-2-phenoxymethyl-4-[(1H-tetrazo...)
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287302BDBM50287302((S)-5-Biphenyl-4-yl-4-(4-carboxymethyl-thiazol-2-y...)
Affinity DataIC50: 58nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50403562BDBM50403562(UK-69578 | CHEMBL2062138)
Affinity DataIC50: 65nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287303BDBM50287303((S)-5-Biphenyl-4-yl-4-(5-carboxymethyl-[1,3,4]thia...)
Affinity DataIC50: 92nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287305BDBM50287305((S)-5-Biphenyl-4-yl-4-(4-carboxymethyl-thiazol-2-y...)
Affinity DataIC50: 122nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287298BDBM50287298((S)-5-Biphenyl-4-yl-4-(4-carboxymethyl-1H-imidazol...)
Affinity DataIC50: 218nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287296BDBM50287296((S)-5-Biphenyl-4-yl-4-(1-carboxymethyl-1H-imidazol...)
Affinity DataIC50: 763nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article