Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50037205
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134098BDBM50134098((3aR,10S)-2-Cyclohexyl-10-(4-methoxy-phenyl)-3a,4,...)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134100BDBM50134100((3aR,10R)-2-Benzyl-10-(4-methoxy-phenyl)-3a,4,9,10...)
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134099BDBM50134099((3aR,10S)-2-Butyl-10-(4-methoxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134106BDBM50134106((3aR,10S)-10-(4-Methoxy-phenyl)-2-(2-pyridin-2-yl-...)
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14390BDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134107BDBM50134107((3aR,10R)-2-Cyclohexyl-10-(4-methoxy-phenyl)-3a,4,...)
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134117BDBM50134117((3aR,10S)-2-Ethyl-10-(4-methoxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134093BDBM50134093((3aR,10R)-2-Butyl-10-(4-methoxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134111BDBM50134111((3aR,10R)-2-Ethyl-10-(4-methoxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134105BDBM50134105((3aR,10R)-10-(4-Methoxy-phenyl)-2-methyl-3a,4,9,10...)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134103BDBM50134103((3aR,10S)-2-Benzyl-10-(4-methoxy-phenyl)-3a,4,9,10...)
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134104BDBM50134104(Trans-2-Butyl-10-(4-chloro-phenyl)-3a,4,9,10-tetra...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134108BDBM50134108((3aR,10S)-10-(4-Methoxy-phenyl)-3a,4,9,10-tetrahyd...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134097BDBM50134097((3aR,10S)-10-(4-Methoxy-phenyl)-2-pyridin-3-ylmeth...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134094BDBM50134094(Trans-2-Butyl-10-phenyl-3a,4,9,10-tetrahydro-2,9,1...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134114BDBM50134114((3aR,10S)-2-(2-Dimethylamino-ethyl)-10-(4-methoxy-...)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134120BDBM50134120(Cis-2-Butyl-10-thiophen-3-yl-3a,4,9,10-tetrahydro-...)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134101BDBM50134101(Cis-2-Butyl-10-(4-chloro-phenyl)-3a,4,9,10-tetrahy...)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134102BDBM50134102((3aR,10R)-2-Butyl-10-(3-chloro-phenyl)-3a,4,9,10-t...)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134115BDBM50134115((3aR,10S)-2-Butyl-10-(3-chloro-phenyl)-3a,4,9,10-t...)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134112BDBM50134112((3aR,10R)-2-Butyl-10-phenyl-3a,4,9,10-tetrahydro-2...)
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134121BDBM50134121((3aR,10R)-2-Butyl-10-pyridin-3-yl-3a,4,9,10-tetrah...)
Affinity DataIC50: 90nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134095BDBM50134095((3aR,10S)-10-(4-Methoxy-phenyl)-2-(2-pyrrolidin-1-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134113BDBM50134113((3aR,10R)-2-Butyl-10-furan-3-yl-3a,4,9,10-tetrahyd...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14363BDBM14363(5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134096BDBM50134096(Cis-2-Butyl-10-pyridin-4-yl-3a,4,9,10-tetrahydro-2...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134110BDBM50134110(4-((3aR,10S)-2-Butyl-1,3-dioxo-2,3,3a,4,9,10-hexah...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001486BDBM50001486(9H-beta-Carboline-3-carboxylic acid ethyl ester | ...)
Affinity DataIC50: 800nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134116BDBM50134116(Cis-4-(2-Butyl-1,3-dioxo-2,3,3a,4,9,10-hexahydro-1...)
Affinity DataIC50: 900nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134109BDBM50134109((3aR,10S)-2-Butyl-10-(2-methoxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134118BDBM50134118((3aR,10S)-2-Butyl-10-(4-methoxy-phenyl)-9-methyl-3...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetPhosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134107BDBM50134107((3aR,10R)-2-Cyclohexyl-10-(4-methoxy-phenyl)-3a,4,...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of bovine aorta PDE3 (phosphodiesterase 3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetPhosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14390BDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of bovine aorta PDE3 (phosphodiesterase 3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetPhosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14363BDBM14363(5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of bovine aorta PDE3 (phosphodiesterase 3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetPhosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134100BDBM50134100((3aR,10R)-2-Benzyl-10-(4-methoxy-phenyl)-3a,4,9,10...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of bovine aorta PDE3 (phosphodiesterase 3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134119BDBM50134119((3aR,10R)-2-Butyl-10-(4-methoxy-phenyl)-9-methyl-3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134100BDBM50134100((3aR,10R)-2-Benzyl-10-(4-methoxy-phenyl)-3a,4,9,10...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PDE2 (phosphodiesterase 2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14363BDBM14363(5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PDE2 (phosphodiesterase 2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetPhosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134093BDBM50134093((3aR,10R)-2-Butyl-10-(4-methoxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of bovine aorta PDE3 (phosphodiesterase 3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetPhosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134099BDBM50134099((3aR,10S)-2-Butyl-10-(4-methoxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of bovine aorta PDE3 (phosphodiesterase 3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134107BDBM50134107((3aR,10R)-2-Cyclohexyl-10-(4-methoxy-phenyl)-3a,4,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PDE2 (phosphodiesterase 2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134093BDBM50134093((3aR,10R)-2-Butyl-10-(4-methoxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PDE2 (phosphodiesterase 2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14390BDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PDE2 (phosphodiesterase 2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134099BDBM50134099((3aR,10S)-2-Butyl-10-(4-methoxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PDE2 (phosphodiesterase 2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed