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Found 23 Enz. Inhib. hit(s) with all data for entry = 50045759
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50112086(3-({2-[(4-Carbamimidoyl-phenylamino)-methyl]-1-met...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50079891(CHEMBL3415214)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50079890(CHEMBL3415215)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50079958(CHEMBL3415062)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50079897(CHEMBL3415209)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50079967(CHEMBL3415059)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50079969(CHEMBL3415058)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50079970(CHEMBL3415057)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50079893(CHEMBL3414580)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50079895(CHEMBL3415211)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50079959(CHEMBL3415061)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50079937(CHEMBL3415064)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50079973(CHEMBL3415055)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50079972(CHEMBL3415056)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50079936(CHEMBL3415065)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50079896(CHEMBL3415210)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50038001((2R,4R)-1-((S)-5-(diaminomethyleneamino)-2-(3-meth...)
Affinity DataIC50:  9.5nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50079892(CHEMBL3415213)
Affinity DataIC50:  14nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50079960(CHEMBL3415060)
Affinity DataIC50:  16nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50079889(CHEMBL3415216)
Affinity DataIC50:  19nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50079898(CHEMBL3415066)
Affinity DataIC50:  22nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50079894(CHEMBL3415212)
Affinity DataIC50:  23nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50079957(CHEMBL3415063)
Affinity DataIC50:  24nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed