Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50046219
TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100592BDBM50100592(CHEMBL3321889)
Affinity DataIC50: 8nMAssay Description:Inhibition of BChE in rat serum using butyrylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100597BDBM50100597(CHEMBL3321877)
Affinity DataIC50: 10nMAssay Description:Inhibition of BChE in rat serum using butyrylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8960BDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 11nMAssay Description:Inhibition of AChE in rat cortex homogenates using acetylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100578BDBM50100578(CHEMBL3321887)
Affinity DataIC50: 12nMAssay Description:Inhibition of BChE in rat serum using butyrylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100594BDBM50100594(CHEMBL3321874)
Affinity DataIC50: 18nMAssay Description:Inhibition of BChE in rat serum using butyrylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100576BDBM50100576(CHEMBL3321885)
Affinity DataIC50: 24nMAssay Description:Inhibition of BChE in rat serum using butyrylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100570BDBM50100570(CHEMBL3321879)
Affinity DataIC50: 29nMAssay Description:Inhibition of BChE in rat serum using butyrylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100572BDBM50100572(CHEMBL3321881)
Affinity DataIC50: 34nMAssay Description:Inhibition of BChE in rat serum using butyrylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100579BDBM50100579(CHEMBL3321888)
Affinity DataIC50: 35nMAssay Description:Inhibition of BChE in rat serum using butyrylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100595BDBM50100595(CHEMBL3321875)
Affinity DataIC50: 63nMAssay Description:Inhibition of BChE in rat serum using butyrylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100571BDBM50100571(CHEMBL3321880)
Affinity DataIC50: 79nMAssay Description:Inhibition of BChE in rat serum using butyrylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100574BDBM50100574(CHEMBL3321883)
Affinity DataIC50: 82nMAssay Description:Inhibition of BChE in rat serum using butyrylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100576BDBM50100576(CHEMBL3321885)
Affinity DataIC50: 97nMAssay Description:Inhibition of AChE in rat cortex homogenates using acetylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100579BDBM50100579(CHEMBL3321888)
Affinity DataIC50: 110nMAssay Description:Inhibition of AChE in rat cortex homogenates using acetylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100592BDBM50100592(CHEMBL3321889)
Affinity DataIC50: 110nMAssay Description:Inhibition of AChE in rat cortex homogenates using acetylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100569BDBM50100569(CHEMBL3321878)
Affinity DataIC50: 120nMAssay Description:Inhibition of BChE in rat serum using butyrylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100578BDBM50100578(CHEMBL3321887)
Affinity DataIC50: 130nMAssay Description:Inhibition of AChE in rat cortex homogenates using acetylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100575BDBM50100575(CHEMBL3321884)
Affinity DataIC50: 130nMAssay Description:Inhibition of BChE in rat serum using butyrylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100594BDBM50100594(CHEMBL3321874)
Affinity DataIC50: 190nMAssay Description:Inhibition of AChE in rat cortex homogenates using acetylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100595BDBM50100595(CHEMBL3321875)
Affinity DataIC50: 240nMAssay Description:Inhibition of AChE in rat cortex homogenates using acetylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100573BDBM50100573(CHEMBL3321882)
Affinity DataIC50: 270nMAssay Description:Inhibition of BChE in rat serum using butyrylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100593BDBM50100593(CHEMBL3321890)
Affinity DataIC50: 310nMAssay Description:Inhibition of BChE in rat serum using butyrylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10620BDBM10620(3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-me...)
Affinity DataIC50: 370nMAssay Description:Inhibition of BChE in rat serum using butyrylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100577BDBM50100577(CHEMBL3321886)
Affinity DataIC50: 430nMAssay Description:Inhibition of BChE in rat serum using butyrylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100597BDBM50100597(CHEMBL3321877)
Affinity DataIC50: 660nMAssay Description:Inhibition of AChE in rat cortex homogenates using acetylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8960BDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of BChE in rat serum using butyrylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100572BDBM50100572(CHEMBL3321881)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of AChE in rat cortex homogenates using acetylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100571BDBM50100571(CHEMBL3321880)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of AChE in rat cortex homogenates using acetylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100577BDBM50100577(CHEMBL3321886)
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of AChE in rat cortex homogenates using acetylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100574BDBM50100574(CHEMBL3321883)
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of AChE in rat cortex homogenates using acetylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10620BDBM10620(3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-me...)
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibition of AChE in rat cortex homogenates using acetylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100575BDBM50100575(CHEMBL3321884)
Affinity DataIC50: 2.77E+3nMAssay Description:Inhibition of AChE in rat cortex homogenates using acetylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100570BDBM50100570(CHEMBL3321879)
Affinity DataIC50: 2.87E+3nMAssay Description:Inhibition of AChE in rat cortex homogenates using acetylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100596BDBM50100596(CHEMBL3321876)
Affinity DataIC50: 3.13E+3nMAssay Description:Inhibition of BChE in rat serum using butyrylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100593BDBM50100593(CHEMBL3321890)
Affinity DataIC50: 4.98E+3nMAssay Description:Inhibition of AChE in rat cortex homogenates using acetylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100569BDBM50100569(CHEMBL3321878)
Affinity DataIC50: 2.08E+4nMAssay Description:Inhibition of AChE in rat cortex homogenates using acetylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100596BDBM50100596(CHEMBL3321876)
Affinity DataIC50: 2.27E+4nMAssay Description:Inhibition of AChE in rat cortex homogenates using acetylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100573BDBM50100573(CHEMBL3321882)
Affinity DataIC50: 2.33E+4nMAssay Description:Inhibition of AChE in rat cortex homogenates using acetylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed