Compile Data Set for Download or QSAR
Report error Found 64 Enz. Inhib. hit(s) with all data for entry = 50048941
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230355(CHEMBL4061884)
Affinity DataKd:  180nMAssay Description:Binding affinity to PHGDH (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM195606(NCT-503)
Affinity DataIC50: 2.50E+3nMAssay Description:Non-competitive inhibition of PHGDH (unknown origin) assessed as reduction in NADH formation using 3-phosphoglycerate as substrate after 20 mins in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230356((3,4-DICHLOROPHENYL)(MORPHOLINO)METHANETHIONE)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230354(CHEMBL4084694)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230347(CHEMBL4096521)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230356((3,4-DICHLOROPHENYL)(MORPHOLINO)METHANETHIONE)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230353(CHEMBL4075188)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230354(CHEMBL4084694)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230350(CHEMBL4087895)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230352(CHEMBL4086943)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230347(CHEMBL4096521)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli assessed as reduction in NADH formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230353(CHEMBL4075188)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230347(CHEMBL4096521)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230356((3,4-DICHLOROPHENYL)(MORPHOLINO)METHANETHIONE)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of recombinant human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli assessed as reduction in NADH formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230350(CHEMBL4087895)
Affinity DataIC50: 1.69E+4nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230354(CHEMBL4084694)
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230352(CHEMBL4086943)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230356((3,4-DICHLOROPHENYL)(MORPHOLINO)METHANETHIONE)
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230353(CHEMBL4075188)
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230350(CHEMBL4087895)
Affinity DataIC50: 2.04E+4nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230347(CHEMBL4096521)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230354(CHEMBL4084694)
Affinity DataIC50: 2.28E+4nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230356((3,4-DICHLOROPHENYL)(MORPHOLINO)METHANETHIONE)
Affinity DataIC50: 2.43E+4nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230353(CHEMBL4075188)
Affinity DataIC50: 2.57E+4nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230352(CHEMBL4086943)
Affinity DataKi:  2.70E+4nMAssay Description:Non-competitive inhibition of recombinant human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli assessed as reduction i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230352(CHEMBL4086943)
Affinity DataIC50: 3.09E+4nMAssay Description:Inhibition of recombinant human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli assessed as reduction in NADH formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230362(CHEMBL4070806)
Affinity DataIC50: 3.30E+4nMAssay Description:Non-competitive inhibition of His6-tagged full length PHGDH (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in NADH f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230354(CHEMBL4084694)
Affinity DataIC50: 3.51E+4nMAssay Description:Inhibition of recombinant human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli assessed as reduction in NADH formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230350(CHEMBL4087895)
Affinity DataIC50: 3.72E+4nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230352(CHEMBL4086943)
Affinity DataKi:  4.00E+4nMAssay Description:Non-competitive inhibition of recombinant human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli assessed as reduction i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230344(CHEMBL4060605)
Affinity DataIC50: 4.33E+4nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230347(CHEMBL4096521)
Affinity DataIC50: 5.05E+4nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230351(CHEMBL4061896)
Affinity DataIC50: 5.75E+4nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230344(CHEMBL4060605)
Affinity DataIC50: 6.44E+4nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230344(CHEMBL4060605)
Affinity DataIC50: 6.89E+4nMAssay Description:Inhibition of recombinant human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli assessed as reduction in NADH formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230352(CHEMBL4086943)
Affinity DataIC50: 7.17E+4nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230351(CHEMBL4061896)
Affinity DataIC50: 7.52E+4nMAssay Description:Inhibition of recombinant human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli assessed as reduction in NADH formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230351(CHEMBL4061896)
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230361(CHEMBL4094885)
Affinity DataIC50: 8.81E+4nMAssay Description:Inhibition of recombinant human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli assessed as reduction in NADH formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230345(CHEMBL4088826)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230352(CHEMBL4086943)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230344(CHEMBL4060605)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230345(CHEMBL4088826)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230351(CHEMBL4061896)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230346(CHEMBL4069286)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230351(CHEMBL4061896)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230345(CHEMBL4088826)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230344(CHEMBL4060605)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230346(CHEMBL4069286)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230345(CHEMBL4088826)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
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