Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50035530
TargetThymidylate synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50028107(thvmidvlate svnthase inhibitor 2b | 2-{4-[(2-Amino...)
Affinity DataKi:  58nMAssay Description:Inhibitory activity against human thymidylate synthase with variable concentration of dUMP and fixed N5,10-CH2-H4PteGlu (200 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50028107(thvmidvlate svnthase inhibitor 2b | 2-{4-[(2-Amino...)
Affinity DataKi:  250nMAssay Description:Inhibitory activity against human thymidylate synthase with variable concentration of dUMP and fixed N5,10-CH2-H4PteGlu (200 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50028108(Phosphoric acid mono-[5-(2,4-dioxo-3,4-dihydro-2H-...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibitory activity against human thymidylate synthase with variable concentration of dUMP and fixed N5,10-CH2-H4PteGlu (200 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50028109(2-{4-[(2-Amino-5-{1-[4-hydroxy-5-(hydroxy-methoxy-...)
Affinity DataKi:  1.20E+5nMAssay Description:Inhibitory activity against human thymidylate synthase with variable concentration of dUMP and fixed N5,10-CH2-H4PteGlu (200 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50028110(2-[4-({2-Amino-5-[1-(4-hydroxy-5-hydroxymethyl-tet...)
Affinity DataKi:  1.50E+5nMAssay Description:Inhibitory activity against human thymidylate synthase with variable concentration of dUMP and fixed N5,10-CH2-H4PteGlu (200 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50028106(diethyl 2-{4-[2-amino-4-oxo-3,4,5,6,7,8-hexahydrop...)
Affinity DataKi:  1.50E+5nMAssay Description:Inhibitory activity against human thymidylate synthase with variable concentration of N5, 10-CH2-H4PteGlu and fixed dUMP (100 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50028106(diethyl 2-{4-[2-amino-4-oxo-3,4,5,6,7,8-hexahydrop...)
Affinity DataKi:  1.50E+5nMAssay Description:Inhibitory activity against human thymidylate synthase with variable concentration of N5, 10-CH2-H4PteGlu and fixed dUMP (100 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50028110(2-[4-({2-Amino-5-[1-(4-hydroxy-5-hydroxymethyl-tet...)
Affinity DataKi:  2.40E+5nMAssay Description:Inhibitory activity against human thymidylate synthase with variable concentration of dUMP and fixed N5,10-CH2-H4PteGlu (200 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50028109(2-{4-[(2-Amino-5-{1-[4-hydroxy-5-(hydroxy-methoxy-...)
Affinity DataKi:  7.00E+5nMAssay Description:Inhibitory activity against human thymidylate synthase with variable concentration of dUMP and fixed N5,10-CH2-H4PteGlu (200 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed