Compile Data Set for Download or QSAR
Report error Found 82 Enz. Inhib. hit(s) with all data for entry = 50036330
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035141BDBM50035141(1'-(cyclohexylbutyl)-3H-spiro[2-benzofuran-1,4'-pi...)
Affinity DataIC50: 0.0700nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035145BDBM50035145(1'-(3-cyclohexyloxypropyl)-3H-spiro[2-benzofuran-1...)
Affinity DataIC50: 0.0700nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035105BDBM50035105(Siramesine | Lu 28-179 | 1'-{4-[1-(4-fluorophenyl)...)
Affinity DataIC50: 0.120nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035133BDBM50035133(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}spiro...)
Affinity DataIC50: 0.140nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035144BDBM50035144(1'-(2-phenylhexyl)-3H-spiro[2-benzofuran-1,4'-pipe...)
Affinity DataIC50: 0.200nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035122BDBM50035122(1'-(2-phenylpentyl)-3H-spiro[2-benzofuran-1,4'-pip...)
Affinity DataIC50: 0.200nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035129BDBM50035129(1'-(2-phenylbutyl)-3H-spiro[2-benzofuran-1,4'-pipe...)
Affinity DataIC50: 0.25nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035097BDBM50035097(CHEMBL303336 | 1''-benzylspiro[1,2,3,4-tetrahydron...)
Affinity DataIC50: 0.260nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035134BDBM50035134(1'-(3-(cyclohexylthio)propyl)-3H-spiro[2-benzofura...)
Affinity DataIC50: 0.260nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035129BDBM50035129(1'-(2-phenylbutyl)-3H-spiro[2-benzofuran-1,4'-pipe...)
Affinity DataIC50: 0.270nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035142BDBM50035142(1-[1-(4-fluorophenyl)-1H-3-indolyl]-4-[6-fluorospi...)
Affinity DataIC50: 0.310nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035135BDBM50035135(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}spiro...)
Affinity DataIC50: 0.340nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035145BDBM50035145(1'-(3-cyclohexyloxypropyl)-3H-spiro[2-benzofuran-1...)
Affinity DataIC50: 0.400nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035144BDBM50035144(1'-(2-phenylhexyl)-3H-spiro[2-benzofuran-1,4'-pipe...)
Affinity DataIC50: 0.530nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035128BDBM50035128(1'-(2-phenylpropyl)-3H-spiro[2-benzofuran-1,4'-pip...)
Affinity DataIC50: 0.560nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035124BDBM50035124(1-[1-(4-fluorophenyl)-1H-3-indolyl]-4-[7-fluorospi...)
Affinity DataIC50: 0.580nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21398BDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 0.650nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035122BDBM50035122(1'-(2-phenylpentyl)-3H-spiro[2-benzofuran-1,4'-pip...)
Affinity DataIC50: 0.820nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035120BDBM50035120(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}spiro...)
Affinity DataIC50: 0.900nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035134BDBM50035134(1'-(3-(cyclohexylthio)propyl)-3H-spiro[2-benzofura...)
Affinity DataIC50: 0.960nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035128BDBM50035128(1'-(2-phenylpropyl)-3H-spiro[2-benzofuran-1,4'-pip...)
Affinity DataIC50: 1.10nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035138BDBM50035138(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}spiro...)
Affinity DataIC50: 1.10nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035141BDBM50035141(1'-(cyclohexylbutyl)-3H-spiro[2-benzofuran-1,4'-pi...)
Affinity DataIC50: 1.5nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035137BDBM50035137(1-[1-(4-fluorophenyl)-1H-3-indolyl]-4-[4-fluorospi...)
Affinity DataIC50: 1.80nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035151BDBM50035151(1'-(2-phenylethyl)-3H-spiro[2-benzofuran-1,4'-pipe...)
Affinity DataIC50: 2.20nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035150BDBM50035150(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}-5-me...)
Affinity DataIC50: 2.30nMAssay Description:Binding affinity towards Sigma receptor type 2 in whole rat brain homogenates except cerebellum using radioligand ([3H]DTG) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035127BDBM50035127(1'-butyl-3H-spiro[2-benzofuran-1,4'-piperidine] | ...)
Affinity DataIC50: 2.5nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50002218BDBM50002218(CHEMBL42228 | CHEMBL543412 | 2-(1-Cyclopropylmethy...)
Affinity DataIC50: 2.60nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035139BDBM50035139(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}-4-tr...)
Affinity DataIC50: 2.60nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035151BDBM50035151(1'-(2-phenylethyl)-3H-spiro[2-benzofuran-1,4'-pipe...)
Affinity DataIC50: 2.90nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035152BDBM50035152(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}spiro...)
Affinity DataIC50: 3nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035131BDBM50035131((1S,9S,13S)-1,13-dimethyl-10-(3-methylbut-2-enyl)-...)
Affinity DataIC50: 3nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035135BDBM50035135(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}spiro...)
Affinity DataIC50: 3.40nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035121BDBM50035121(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}spiro...)
Affinity DataIC50: 3.80nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035143BDBM50035143(1'-propyl-3H-spiro[2-benzofuran-1,4'-piperidine] |...)
Affinity DataIC50: 4.70nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035142BDBM50035142(1-[1-(4-fluorophenyl)-1H-3-indolyl]-4-[6-fluorospi...)
Affinity DataIC50: 5.5nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035123BDBM50035123(1'-[3-(methylsulfonyl)propyl]-3H-spiro[2-benzofura...)
Affinity DataIC50: 6.30nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035126BDBM50035126(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}-6-tr...)
Affinity DataIC50: 7nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035152BDBM50035152(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}spiro...)
Affinity DataIC50: 7nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035127BDBM50035127(1'-butyl-3H-spiro[2-benzofuran-1,4'-piperidine] | ...)
Affinity DataIC50: 7.30nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407300BDBM50407300(CHEMBL397705)
Affinity DataIC50: 8.90nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035150BDBM50035150(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}-5-me...)
Affinity DataIC50: 9.5nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035121BDBM50035121(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}spiro...)
Affinity DataIC50: 12nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035097BDBM50035097(CHEMBL303336 | 1''-benzylspiro[1,2,3,4-tetrahydron...)
Affinity DataIC50: 12nMAssay Description:Binding affinity towards Sigma receptor type 2 in whole rat brain homogenates except cerebellum using radioligand ([3H]DTG) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035105BDBM50035105(Siramesine | Lu 28-179 | 1'-{4-[1-(4-fluorophenyl)...)
Affinity DataIC50: 17nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21398BDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 17nMAssay Description:Binding affinity towards Sigma receptor type 2 in whole rat brain homogenates except cerebellum using radioligand ([3H]DTG) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035148BDBM50035148(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}spiro...)
Affinity DataIC50: 23nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035138BDBM50035138(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}spiro...)
Affinity DataIC50: 23nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50002218BDBM50002218(CHEMBL42228 | CHEMBL543412 | 2-(1-Cyclopropylmethy...)
Affinity DataIC50: 23nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035143BDBM50035143(1'-propyl-3H-spiro[2-benzofuran-1,4'-piperidine] |...)
Affinity DataIC50: 23nMAssay Description:Binding affinity towards Sigma receptor type 2 in whole rat brain homogenates except cerebellum using radioligand ([3H]DTG) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
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