Compile Data Set for Download or QSAR
maximum 50k data
Found 34 Enz. Inhib. hit(s) with all data for entry = 50007171
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059319(1-[(R)-5-(3-Aza-bicyclo[3.2.2]non-3-yl)-1-methyl-2...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of ligand binding to Cholecystokinin type B receptor from guinea pig cortical membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040666(1-((R)-5-Cyclohexyl-1-methyl-2-oxo-2,3-dihydro-1H-...)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of ligand binding to Cholecystokinin type B receptor from guinea pig cortical membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043493(CHEMBL313813 | N,N-Diethyl-2-[2-oxo-5-pyridin-2-yl...)
Affinity DataIC50:  0.560nMAssay Description:Inhibition of ligand binding to Cholecystokinin type B receptor from guinea pig cortical membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059320(1-[(R)-5-((R)-4,4-Dimethyl-piperidin-2-yl)-2-oxo-1...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of ligand binding to Cholecystokinin type B receptor from guinea pig cortical membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040664(1-(5-Azepan-1-yl-1-methyl-2-oxo-2,3-dihydro-1H-ben...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of ligand binding to Cholecystokinin type B receptor from guinea pig cortical membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059327(1-[(R)-5-((R)-4,4-Dimethyl-piperidin-2-yl)-2-oxo-1...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of ligand binding to Cholecystokinin type B receptor from guinea pig cortical membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059325(1-[(R)-5-((R)-4,4-Dimethyl-piperidin-2-yl)-1-methy...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of ligand binding to Cholecystokinin type B receptor from guinea pig cortical membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006878((R)-1-(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Affinity DataIC50:  8.5nMAssay Description:The concentration of the compound required for half maximal inhibition of the binding to Cholecystokinin type B receptor (CCK-B) from guinea pigcorti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040664(1-(5-Azepan-1-yl-1-methyl-2-oxo-2,3-dihydro-1H-ben...)
Affinity DataIC50:  10nMAssay Description:Inhibition of ligand binding to Cholecystokinin type A receptor receptor from rat pancreatic tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059326(1-[(R)-5-((R)-5,5-Dimethyl-azepan-2-yl)-1-methyl-2...)
Affinity DataIC50:  12nMAssay Description:Inhibition of ligand binding to Cholecystokinin type B receptor from guinea pig cortical membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059322(1-[(R)-5-((R)-5,5-Dimethyl-azepan-2-yl)-2-oxo-1-pr...)
Affinity DataIC50:  15nMAssay Description:Inhibition of ligand binding to Cholecystokinin type B receptor from guinea pig cortical membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059324(2-[(R)-1-Diethylcarbamoylmethyl-2-oxo-3-(3-m-tolyl...)
Affinity DataIC50:  18nMAssay Description:Inhibition of ligand binding to Cholecystokinin type B receptor from guinea pig cortical membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059329(1-[(R)-2-Oxo-1-propyl-5-((R)-1,5,5-trimethyl-azepa...)
Affinity DataIC50:  26nMAssay Description:Inhibition of ligand binding to Cholecystokinin type B receptor from guinea pig cortical membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059328(1-((R)-2-Oxo-5-(R)-piperidin-2-yl-1-propyl-2,3-dih...)
Affinity DataIC50:  36nMAssay Description:Inhibition of ligand binding to Cholecystokinin type B receptor from guinea pig cortical membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059323(1-((R)-2-Oxo-5-(S)-piperidin-2-yl-1-propyl-2,3-dih...)
Affinity DataIC50:  41nMAssay Description:Inhibition of ligand binding to Cholecystokinin type B receptor from guinea pig cortical membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059321(1-[(R)-5-((R)-1-Methyl-piperidin-2-yl)-2-oxo-1-pro...)
Affinity DataIC50:  54nMAssay Description:Inhibition of ligand binding to Cholecystokinin type B receptor from guinea pig cortical membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043500(1-(1-Methyl-2-oxo-5-pyridin-2-yl-2,3-dihydro-1H-be...)
Affinity DataIC50:  65nMAssay Description:Inhibition of ligand binding to Cholecystokinin type A receptor receptor from rat pancreatic tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043500(1-(1-Methyl-2-oxo-5-pyridin-2-yl-2,3-dihydro-1H-be...)
Affinity DataIC50:  66nMAssay Description:Inhibition of ligand binding to Cholecystokinin type B receptor from guinea pig cortical membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040669(1-(1-Methyl-2-oxo-5-pyrrolidin-1-yl-2,3-dihydro-1H...)
Affinity DataIC50:  137nMAssay Description:Inhibition of ligand binding to Cholecystokinin type B receptor from guinea pig cortical membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043493(CHEMBL313813 | N,N-Diethyl-2-[2-oxo-5-pyridin-2-yl...)
Affinity DataIC50:  435nMAssay Description:Inhibition of ligand binding to Cholecystokinin type A receptor receptor from rat pancreatic tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040669(1-(1-Methyl-2-oxo-5-pyrrolidin-1-yl-2,3-dihydro-1H...)
Affinity DataIC50:  480nMAssay Description:Inhibition of ligand binding to Cholecystokinin type A receptor receptor from rat pancreatic tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006878((R)-1-(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Affinity DataIC50:  736nMAssay Description:Inhibition of ligand binding to Cholecystokinin type A receptor receptor from rat pancreatic tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059326(1-[(R)-5-((R)-5,5-Dimethyl-azepan-2-yl)-1-methyl-2...)
Affinity DataIC50:  1.39E+3nMAssay Description:Inhibition of ligand binding to Cholecystokinin type A receptor receptor from rat pancreatic tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059322(1-[(R)-5-((R)-5,5-Dimethyl-azepan-2-yl)-2-oxo-1-pr...)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibition of ligand binding to Cholecystokinin type A receptor receptor from rat pancreatic tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059319(1-[(R)-5-(3-Aza-bicyclo[3.2.2]non-3-yl)-1-methyl-2...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of ligand binding to Cholecystokinin type A receptor receptor from rat pancreatic tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059324(2-[(R)-1-Diethylcarbamoylmethyl-2-oxo-3-(3-m-tolyl...)
Affinity DataIC50:  1.75E+3nMAssay Description:Inhibition of ligand binding to Cholecystokinin type A receptor receptor from rat pancreatic tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040666(1-((R)-5-Cyclohexyl-1-methyl-2-oxo-2,3-dihydro-1H-...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of ligand binding to Cholecystokinin type A receptor receptor from rat pancreatic tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059321(1-[(R)-5-((R)-1-Methyl-piperidin-2-yl)-2-oxo-1-pro...)
Affinity DataIC50:  2.09E+3nMAssay Description:Inhibition of ligand binding to Cholecystokinin type A receptor receptor from rat pancreatic tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059323(1-((R)-2-Oxo-5-(S)-piperidin-2-yl-1-propyl-2,3-dih...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of ligand binding to Cholecystokinin type A receptor receptor from rat pancreatic tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059328(1-((R)-2-Oxo-5-(R)-piperidin-2-yl-1-propyl-2,3-dih...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of ligand binding to Cholecystokinin type A receptor receptor from rat pancreatic tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059327(1-[(R)-5-((R)-4,4-Dimethyl-piperidin-2-yl)-2-oxo-1...)
Affinity DataIC50:  3.09E+3nMAssay Description:Inhibition of ligand binding to Cholecystokinin type A receptor receptor from rat pancreatic tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059329(1-[(R)-2-Oxo-1-propyl-5-((R)-1,5,5-trimethyl-azepa...)
Affinity DataIC50:  3.54E+3nMAssay Description:Inhibition of ligand binding to Cholecystokinin type A receptor receptor from rat pancreatic tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059320(1-[(R)-5-((R)-4,4-Dimethyl-piperidin-2-yl)-2-oxo-1...)
Affinity DataIC50:  4.02E+3nMAssay Description:Inhibition of ligand binding to Cholecystokinin type A receptor receptor from rat pancreatic tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059325(1-[(R)-5-((R)-4,4-Dimethyl-piperidin-2-yl)-1-methy...)
Affinity DataIC50:  6.49E+3nMAssay Description:Inhibition of ligand binding to Cholecystokinin type A receptor receptor from rat pancreatic tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed