Compile Data Set for Download or QSAR
maximum 50k data
Found 19 Enz. Inhib. hit(s) with all data for entry = 50007740
TargetSigma non-opioid intracellular receptor 1(RAT)
Università

Curated by ChEMBL
LigandPNGBDBM50054124(1-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...)
Affinity DataIC50:  0.0890nMAssay Description:Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Università

Curated by ChEMBL
LigandPNGBDBM50054124(1-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...)
Affinity DataIC50:  0.0890nMAssay Description:Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Università

Curated by ChEMBL
LigandPNGBDBM50067018(1-[5-(6-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...)
Affinity DataIC50:  0.620nMAssay Description:Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Università

Curated by ChEMBL
LigandPNGBDBM50054121(3,3-Dimethyl-1-[4-(1,2,3,4-tetrahydro-naphthalen-1...)
Affinity DataIC50:  0.690nMAssay Description:Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Università

Curated by ChEMBL
LigandPNGBDBM50067019(1-[3-(3H-Inden-1-yl)-propyl]-3,3-dimethyl-piperidi...)
Affinity DataIC50:  0.990nMAssay Description:Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Università

Curated by ChEMBL
LigandPNGBDBM50067010(1-(3-Indan-1-yl-propyl)-3,3-dimethyl-piperidine | ...)
Affinity DataIC50:  6.90nMAssay Description:Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Università

Curated by ChEMBL
LigandPNGBDBM50067012(1-[4-(4-Methoxy-indan-1-yl)-butyl]-3,3-dimethyl-pi...)
Affinity DataIC50:  9.30nMAssay Description:Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Università

Curated by ChEMBL
LigandPNGBDBM50067008(1-[3-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...)
Affinity DataIC50:  22nMAssay Description:Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Università

Curated by ChEMBL
LigandPNGBDBM50067016(1-[4-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...)
Affinity DataIC50:  25.6nMAssay Description:Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Università

Curated by ChEMBL
LigandPNGBDBM50067014(5-[3-(3,3-Dimethyl-piperidin-1-yl)-propyl]-5,6,7,8...)
Affinity DataIC50:  41nMAssay Description:Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Università

Curated by ChEMBL
LigandPNGBDBM50067011(3,3-Dimethyl-1-[3-(1,2,3,4-tetrahydro-naphthalen-1...)
Affinity DataIC50:  252nMAssay Description:Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Università

Curated by ChEMBL
LigandPNGBDBM50067013(1-[4-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...)
Affinity DataIC50:  978nMAssay Description:Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Università

Curated by ChEMBL
LigandPNGBDBM50067015(3,3-Dimethyl-1-[5-(1,2,3,4-tetrahydro-naphthalen-1...)
Affinity DataIC50:  1.52E+3nMAssay Description:Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Università

Curated by ChEMBL
LigandPNGBDBM50067020(1-(4-(6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataIC50:  2.15E+3nMAssay Description:Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Università

Curated by ChEMBL
LigandPNGBDBM50067022(1-[3-(5-Methoxy-indan-1-yl)-propyl]-3,3-dimethyl-p...)
Affinity DataIC50:  4.66E+3nMAssay Description:Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Università

Curated by ChEMBL
LigandPNGBDBM50067017(3,3-Dimethyl-1-(5-phenyl-pentyl)-piperidine | CHEM...)
Affinity DataIC50:  5.83E+3nMAssay Description:Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Università

Curated by ChEMBL
LigandPNGBDBM50067021(1-[4-(3,4-Dihydro-naphthalen-1-yl)-butyl]-3,3-dime...)
Affinity DataIC50:  9.45E+3nMAssay Description:Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Università

Curated by ChEMBL
LigandPNGBDBM50067009(3,3-Dimethyl-1-[2-(1,2,3,4-tetrahydro-naphthalen-1...)
Affinity DataIC50: >1.00E+4nMAssay Description:Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Università

Curated by ChEMBL
LigandPNGBDBM50067023(1-(3-(6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed