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Found 16 Enz. Inhib. hit(s) with all data for entry = 50034985
TargetMacrophage metalloelastase(Mus musculus)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50068848((2R,4R)-2-[Benzyl-(4-methoxy-benzenesulfonyl)-amin...)
Affinity DataIC50:  4.80nMAssay Description:Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Mus musculus)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM13126((2R)-2-[benzyl(4-methoxybenzene)sulfonamido]-N-hyd...)
Affinity DataIC50:  4.90nMAssay Description:Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Mus musculus)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50068853((R)-N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyrid...)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Mus musculus)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50068849((R)-2-[(4-Methoxy-benzenesulfonyl)-pyridin-2-ylmet...)
Affinity DataIC50:  6.90nMAssay Description:Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Mus musculus)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  7.70nMAssay Description:Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Mus musculus)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM13119((2R)-2-[benzyl(4-methoxybenzene)sulfonamido]-N-hyd...)
Affinity DataIC50:  9.60nMAssay Description:Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Mus musculus)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM13122((2R)-2-[benzyl(4-methoxybenzene)sulfonamido]-N-hyd...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Mus musculus)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM11337(2-[benzyl(4-methoxybenzene)sulfonamido]-N-hydroxyp...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Mus musculus)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50068850((R)-2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-2...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Mus musculus)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM11343((2S)-2-[benzyl(4-methoxybenzene)sulfonamido]-N-hyd...)
Affinity DataIC50:  16nMAssay Description:Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Mus musculus)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50068851((2R,4S)-2-[Benzyl-(4-methoxy-benzenesulfonyl)-amin...)
Affinity DataIC50:  16nMAssay Description:Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Mus musculus)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM13123((2R)-2-[benzyl(4-methoxybenzene)sulfonamido]-N-hyd...)
Affinity DataIC50:  31nMAssay Description:Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Mus musculus)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM13118((2S)-2-[benzyl(4-methoxybenzene)sulfonamido]-N-hyd...)
Affinity DataIC50:  35nMAssay Description:Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Mus musculus)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50068847((S)-N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyrid...)
Affinity DataIC50:  37nMAssay Description:Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Mus musculus)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50068852(CHEMBL265476 | {(R)-5-[Benzyl-(4-methoxy-benzenesu...)
Affinity DataIC50:  67nMAssay Description:Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Mus musculus)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50068854((R)-2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N...)
Affinity DataIC50: >100nMAssay Description:Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed