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Found 29 Enz. Inhib. hit(s) with all data for entry = 50008064
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070409(2-(5-(2-(8-(4-methylpiperazin-1-yl)naphthalen-2-yl...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1D receptor using [3H]-5-CT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070406(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-N-(4-{2-[8-...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1D receptor using [3H]-5-CT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070406(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-N-(4-{2-[8-...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1B receptor using [3H]-5-CT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070409(2-(5-(2-(8-(4-methylpiperazin-1-yl)naphthalen-2-yl...)
Affinity DataKi:  0.760nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1B receptor using [3H]-5-CT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070409(2-(5-(2-(8-(4-methylpiperazin-1-yl)naphthalen-2-yl...)
Affinity DataKi:  0.960nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070408(2-[8-(4-Methyl-piperazin-1-yl)-naphthalen-2-yloxy]...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1D receptor using [3H]-5-CT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070405(1,2-di[8-(4-methylhexahydro-1-pyrazinyl)-2-naphthy...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1D receptor using [3H]-5-CT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070405(1,2-di[8-(4-methylhexahydro-1-pyrazinyl)-2-naphthy...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1B receptor using [3H]-5-CT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070408(2-[8-(4-Methyl-piperazin-1-yl)-naphthalen-2-yloxy]...)
Affinity DataKi:  2.60nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1B receptor using [3H]-5-CT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070407(2N,2N-dipropyl-8-[6-(3-dipropylamino-1,2,3,4-tetra...)
Affinity DataKi:  3.90nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1D receptor using [3H]-5-CT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070408(2-[8-(4-Methyl-piperazin-1-yl)-naphthalen-2-yloxy]...)
Affinity DataKi:  4nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataKi:  5.10nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1D receptor using [3H]-5-CT as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070406(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-N-(4-{2-[8-...)
Affinity DataKi:  5.80nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50007407(1-NP | 1-Naphthalen-1-yl-piperazine | 4-Naphthalen...)
Affinity DataKi:  6.20nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1D receptor using [3H]-5-CT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070407(2N,2N-dipropyl-8-[6-(3-dipropylamino-1,2,3,4-tetra...)
Affinity DataKi:  6.40nMAssay Description:The intrinsic activity of the compound was evaluated for its ability to inhibit forskolin-stimulated c-AMP formation mediated by cloned 5-hydroxytryp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070407(2N,2N-dipropyl-8-[6-(3-dipropylamino-1,2,3,4-tetra...)
Affinity DataKi:  6.80nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataKi:  6.80nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1B receptor using [3H]-5-CT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50007407(1-NP | 1-Naphthalen-1-yl-piperazine | 4-Naphthalen...)
Affinity DataKi:  9.20nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50007407(1-NP | 1-Naphthalen-1-yl-piperazine | 4-Naphthalen...)
Affinity DataKi:  11nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1B receptor using [3H]-5-CT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070405(1,2-di[8-(4-methylhexahydro-1-pyrazinyl)-2-naphthy...)
Affinity DataKi:  14nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Affinity DataKi:  115nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1D receptor using [3H]-5-CT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Affinity DataKi:  559nMAssay Description:The intrinsic activity of the compound was evaluated for its ability to inhibit forskolin-stimulated c-AMP formation mediated by cloned 5-hydroxytryp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070405(1,2-di[8-(4-methylhexahydro-1-pyrazinyl)-2-naphthy...)
Affinity DataEC50: >1.00E+3nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1B receptor using [3H]-5-CT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50007407(1-NP | 1-Naphthalen-1-yl-piperazine | 4-Naphthalen...)
Affinity DataEC50: >1.00E+4nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1B receptor using [3H]-5-CT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataEC50:  4.70nMAssay Description:The intrinsic activity of the compound was evaluated for its ability to inhibit forskolin-stimulated c-AMP formation mediated by cloned 5-hydroxytryp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Affinity DataEC50:  260nMAssay Description:The intrinsic activity of the compound was evaluated for its ability to inhibit forskolin-stimulated c-AMP formation mediated by cloned 5-hydroxytryp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070407(2N,2N-dipropyl-8-[6-(3-dipropylamino-1,2,3,4-tetra...)
Affinity DataEC50:  50nMAssay Description:The intrinsic activity of the compound was evaluated for its ability to inhibit forskolin-stimulated c-AMP formation mediated by cloned 5-hydroxytryp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed