Compile Data Set for Download or QSAR
maximum 50k data
Found 39 Enz. Inhib. hit(s) with all data for entry = 50008154
TargetThromboxane-A synthase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071134((E)-7-{3-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2...)
Affinity DataIC50:  19nMAssay Description:In vitro inhibition of thromboxane synthase (TSI) activity was determined by using human serum levels of TXB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071145((Z)-7-{3-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2...)
Affinity DataIC50:  23nMAssay Description:In vitro inhibition of thromboxane synthase (TSI) activity was determined by using human serum levels of TXB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071131((E)-7-{4-[4-(Cyclopropylmethyl-carbamoyl)-oxazol-2...)
Affinity DataIC50:  25nMAssay Description:In vitro inhibition of thromboxane synthase (TSI) activity was determined by using human serum levels of TXB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071142((E)-7-[4-(4-Benzylcarbamoyl-oxazol-2-yl)-phenyl]-7...)
Affinity DataIC50:  25nMAssay Description:In vitro inhibition of thromboxane synthase (TSI) activity was determined by using human serum levels of TXB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071141((E)-7-[4-(4-Pentylcarbamoyl-oxazol-2-yl)-phenyl]-7...)
Affinity DataIC50:  31nMAssay Description:In vitro inhibition of thromboxane synthase (TSI) activity was determined by using human serum levels of TXB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071140((E)-8-{4-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2...)
Affinity DataIC50:  38nMAssay Description:In vitro inhibition of thromboxane synthase (TSI) activity was determined by using human serum levels of TXB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50010960((E)-7-Phenyl-7-pyridin-3-yl-hept-6-enoic acid | 7-...)
Affinity DataIC50:  49nMAssay Description:In vitro inhibition of thromboxane synthase (TSI) activity was determined by using human serum levels of TXB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071132((E)-7-{4-[(S)-4-(4-Cyclohexyl-butylcarbamoyl)-4,5-...)
Affinity DataIC50:  82nMAssay Description:In vitro inhibition of thromboxane synthase (TSI) activity was determined by using human serum levels of TXB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071136((E)-7-{4-[(R)-4-(4-Cyclohexyl-butylcarbamoyl)-4,5-...)
Affinity DataIC50:  82nMAssay Description:In vitro inhibition of thromboxane synthase (TSI) activity was determined by using human serum levels of TXB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071133((E)-6-{4-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2...)
Affinity DataIC50:  230nMAssay Description:In vitro inhibition of thromboxane synthase (TSI) activity was determined by using human serum levels of TXB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071127((E)-7-{4-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2...)
Affinity DataIC50:  550nMAssay Description:In vitro inhibition of thromboxane synthase (TSI) activity was determined by using human serum levels of TXB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071127((E)-7-{4-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2...)
Affinity DataIC50:  550nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071135((E)-5-{4-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2...)
Affinity DataIC50:  3.17E+3nMAssay Description:In vitro inhibition of thromboxane synthase (TSI) activity was determined by using human serum levels of TXB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071129((Z)-7-{4-[(R)-4-(4-Cyclohexyl-butylcarbamoyl)-4,5-...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of thromboxane synthase (TSI) activity was determined by using human serum levels of TXB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071146((Z)-7-{4-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of thromboxane synthase (TSI) activity was determined by using human serum levels of TXB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071129((Z)-7-{4-[(R)-4-(4-Cyclohexyl-butylcarbamoyl)-4,5-...)
Affinity DataKd:  52nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50010960((E)-7-Phenyl-7-pyridin-3-yl-hept-6-enoic acid | 7-...)
Affinity DataKd:  8.20E+3nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071137((Z)-7-{3-[(R)-4-(4-Cyclohexyl-butylcarbamoyl)-4,5-...)
Affinity DataKd:  830nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071134((E)-7-{3-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2...)
Affinity DataKd:  12nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071131((E)-7-{4-[4-(Cyclopropylmethyl-carbamoyl)-oxazol-2...)
Affinity DataKd:  791nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071144((E)-7-{2-[(R)-4-(4-Cyclohexyl-butylcarbamoyl)-4,5-...)
Affinity DataKd:  1.85E+3nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071135((E)-5-{4-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2...)
Affinity DataKd:  93nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071136((E)-7-{4-[(R)-4-(4-Cyclohexyl-butylcarbamoyl)-4,5-...)
Affinity DataKd:  16nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071130((E)-7-[4-((S)-4-Pentylcarbamoyl-4,5-dihydro-oxazol...)
Affinity DataKd:  245nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071127((E)-7-{4-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2...)
Affinity DataKd:  9.90nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071143((E)-7-{2-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2...)
Affinity DataKd:  540nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071142((E)-7-[4-(4-Benzylcarbamoyl-oxazol-2-yl)-phenyl]-7...)
Affinity DataKd:  135nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071141((E)-7-[4-(4-Pentylcarbamoyl-oxazol-2-yl)-phenyl]-7...)
Affinity DataKd:  153nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071140((E)-8-{4-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2...)
Affinity DataKd:  110nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071145((Z)-7-{3-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2...)
Affinity DataKd:  630nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071146((Z)-7-{4-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2...)
Affinity DataKd:  147nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071132((E)-7-{4-[(S)-4-(4-Cyclohexyl-butylcarbamoyl)-4,5-...)
Affinity DataKd:  16nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071128((E)-7-{4-[(S)-4-(Cyclopropylmethyl-carbamoyl)-4,5-...)
Affinity DataKd:  1.12E+3nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071147((Z)-7-{2-[(R)-4-(4-Cyclohexyl-butylcarbamoyl)-4,5-...)
Affinity DataKd:  1.10E+3nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071127((E)-7-{4-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2...)
Affinity DataKd:  9.90nMAssay Description:In vitro inhibition of thromboxane synthase (TSI) activity was determined by using human serum levels of TXB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071139((Z)-7-{2-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2...)
Affinity DataKd:  1.50E+3nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071138((E)-7-[4-((S)-4-Benzylcarbamoyl-4,5-dihydro-oxazol...)
Affinity DataKd:  379nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071133((E)-6-{4-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2...)
Affinity DataKd:  33nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071137((Z)-7-{3-[(R)-4-(4-Cyclohexyl-butylcarbamoyl)-4,5-...)
Affinity DataKd:  452nMAssay Description:In vitro inhibition of thromboxane synthase (TSI) activity was determined by using human serum levels of TXB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed