Compile Data Set for Download or QSAR
Report error Found 77 Enz. Inhib. hit(s) with all data for entry = 3467
TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401275(US10005756, Compound A40)
Affinity DataIC50: 34nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401272(US10005756, Compound A35)
Affinity DataIC50: 39nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401283(US10005756, Compound A50)
Affinity DataIC50: 39nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401245(US10005756, Compound A6)
Affinity DataIC50: 43nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401314(US10005756, Compound A86)
Affinity DataIC50: 49nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401248(US10005756, Compound A9)
Affinity DataIC50: 51nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401270(US10005756, Compound A33)
Affinity DataIC50: 55nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401267(US10005756, Compound A30)
Affinity DataIC50: 58nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401315(US10005756, Compound A87)
Affinity DataIC50: 63nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401301(US10005756, Compound A72)
Affinity DataIC50: 67nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401297(US10005756, Compound A68)
Affinity DataIC50: 68nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401271(US10005756, Compound A34)
Affinity DataIC50: 70nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401247(US10005756, Compound A8)
Affinity DataIC50: 70nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401274(US10005756, Compound A39)
Affinity DataIC50: 73nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401285(US10005756, Compound A52)
Affinity DataIC50: 75nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401249(US10005756, Compound A10)
Affinity DataIC50: 78nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401284(US10005756, Compound A51)
Affinity DataIC50: 79nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401250(US10005756, Compound A11)
Affinity DataIC50: 83nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401299(US10005756, Compound A70)
Affinity DataIC50: 85nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401264(US10005756, Compound A27)
Affinity DataIC50: 89nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401307(US10005756, Compound A78)
Affinity DataIC50: 91nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401304(US10005756, Compound A75)
Affinity DataIC50: 92nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401296(US10005756, Compound A67)
Affinity DataIC50: 96nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401244(US10005756, Compound A5)
Affinity DataIC50: 96nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401286(US10005756, Compound A53)
Affinity DataIC50: 100nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401295(US10005756, Compound A66)
Affinity DataIC50: 100nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401316(US10005756, Compound A89)
Affinity DataIC50: 110nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401298(US10005756, Compound A69)
Affinity DataIC50: 110nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401303(US10005756, Compound A74)
Affinity DataIC50: 120nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401240(US10005756, Compound A1)
Affinity DataIC50: 130nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401289(US10005756, Compound A60)
Affinity DataIC50: 130nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401294(US10005756, Compound A65)
Affinity DataIC50: 130nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401251(US10005756, Compound A13)
Affinity DataIC50: 140nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401265(US10005756, Compound A28)
Affinity DataIC50: 140nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401305(US10005756, Compound A76)
Affinity DataIC50: 150nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401259(US10005756, Compound A22)
Affinity DataIC50: 150nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401308(US10005756, Compound A79)
Affinity DataIC50: 150nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401288(US10005756, Compound A58)
Affinity DataIC50: 160nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401309(US10005756, Compound A80)
Affinity DataIC50: 160nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401255(US10005756, Compound A18)
Affinity DataIC50: 170nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401312(US10005756, Compound A83)
Affinity DataIC50: 170nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401242(US10005756, Compound A3)
Affinity DataIC50: 180nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401266(US10005756, Compound A29)
Affinity DataIC50: 180nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401254(US10005756, Compound A17)
Affinity DataIC50: 190nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401273(US10005756, Compound A38)
Affinity DataIC50: 210nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401258(US10005756, Compound A21)
Affinity DataIC50: 220nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401276(US10005756, Compound A41)
Affinity DataIC50: 220nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401279(US10005756, Compound A44 | US10005756, Compound A4...)
Affinity DataIC50: 240nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401310(US10005756, Compound A81)
Affinity DataIC50: 250nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401281(US10005756, Compound A47)
Affinity DataIC50: 270nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

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