Compile Data Set for Download or QSAR
Report error Found 448 Enz. Inhib. hit(s) with all data for entry = 1426
Target5-hydroxytryptamine receptor 3A(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322432BDBM322432(US10183938, Compound (R)-186 | (R)-7-phenyl-N-(1'-...)
Affinity DataKi:  30nMAssay Description:[3H]BRL 43694 competition binding assay was performed under contract by Cerep Poitiers, France following the methods described in Hope, A. G et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322406BDBM322406(US10183938, Compound (R)-165 | (R)-7-cyclopropyl-N...)
Affinity DataKi:  36nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322274BDBM322274(US10183938, Compound 56a | 7-chloro-N-(1'-azaspiro...)
Affinity DataKi:  37nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322452BDBM322452(US10183938, Compound (R)-205 | (R)-6-chloro-7-meth...)
Affinity DataKi:  47nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322274BDBM322274(US10183938, Compound 56a | 7-chloro-N-(1'-azaspiro...)
Affinity DataKi:  48nMAssay Description:[3H]BRL 43694 competition binding assay was performed under contract by Cerep Poitiers, France following the methods described in Hope, A. G et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322387BDBM322387(US10183938, Compound (R)-150 | (R)-6,7-dichloro-N-...)
Affinity DataKi:  54.5nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322402BDBM322402(US10183938, Compound (R)-161 | (R)-7-methoxy-N-(1'...)
Affinity DataKi:  58nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322271BDBM322271(US10183938, Compound 54a | N-(1''-azaspiro[cyclopr...)
Affinity DataKi:  61nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322275BDBM322275(US10183938, Compound 57a | US10183938, Compound 57...)
Affinity DataKi:  75nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322440BDBM322440(US10183938, Compound (R)-194 | (R)-N-(1'-azaspiro[...)
Affinity DataKi:  79nMAssay Description:[3H]BRL 43694 competition binding assay was performed under contract by Cerep Poitiers, France following the methods described in Hope, A. G et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322427BDBM322427(US10183938, Compound (R)-181 | (R)-N-(1'-azaspiro[...)
Affinity DataKi:  83nMAssay Description:[3H]BRL 43694 competition binding assay was performed under contract by Cerep Poitiers, France following the methods described in Hope, A. G et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322385BDBM322385(US10183938, Compound (R)-148 | (R)-6-chloro-N-(2,2...)
Affinity DataKi:  92nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322280BDBM322280(US10183938, Compound 60a | US10183938, Compound 60...)
Affinity DataKi:  98nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322283BDBM322283(US10183938, Compound 62a | 6-amino-N-(1''-azaspiro...)
Affinity DataKi:  100nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322451BDBM322451(US10183938, Compound (R)-204 | (R)-N-(1'-azaspiro[...)
Affinity DataKi:  100nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322368BDBM322368(US10183938, Compound (R)-132 | (R)-N-(2,2-dimethyl...)
Affinity DataKi:  100nMAssay Description:[3H]BRL 43694 competition binding assay was performed under contract by Cerep Poitiers, France following the methods described in Hope, A. G et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322193BDBM322193(US10183938, Compound (R)-3 | (R)-7-chloro-N-(2,2-d...)
Affinity DataKi:  110nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322430BDBM322430(US10183938, Compound (R)-184 | (R)-7-(tert-butyl)-...)
Affinity DataKi:  110nMAssay Description:[3H]BRL 43694 competition binding assay was performed under contract by Cerep Poitiers, France following the methods described in Hope, A. G et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322275BDBM322275(US10183938, Compound 57a | US10183938, Compound 57...)
Affinity DataKi:  110nMAssay Description:[3H]BRL 43694 competition binding assay was performed under contract by Cerep Poitiers, France following the methods described in Hope, A. G et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322277BDBM322277(US10183938, Compound 58a | N-(1'-azaspiro[cyclopro...)
Affinity DataKi:  110nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322401BDBM322401(US10183938, Compound (R)-160 | (R)-7-cyano-N-(1'-a...)
Affinity DataKi:  110nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322345BDBM322345(US10183938, Compound (R)-109 | (R)-6,7-dichloro-N-...)
Affinity DataKi:  110nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322302BDBM322302(US10183938, Compound 73a | 6-methoxy-N-(1''-azaspi...)
Affinity DataKi:  120nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322422BDBM322422(US10183938, Compound (R)-176 | (R)-7-methyl-N-(1'-...)
Affinity DataKi:  130nMAssay Description:[3H]BRL 43694 competition binding assay was performed under contract by Cerep Poitiers, France following the methods described in Hope, A. G et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322422BDBM322422(US10183938, Compound (R)-176 | (R)-7-methyl-N-(1'-...)
Affinity DataKi:  130nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322362BDBM322362(US10183938, Compound (R)-126 | (R)-N-(2,2-dimethyl...)
Affinity DataKi:  140nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322354BDBM322354(US10183938, Compound (R)-118 | (R)-7-cyclopropyl-N...)
Affinity DataKi:  140nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322427BDBM322427(US10183938, Compound (R)-181 | (R)-N-(1'-azaspiro[...)
Affinity DataKi:  147nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322342BDBM322342(US10183938, Compound (R)-106 | (R)-7-fluoro-6-meth...)
Affinity DataKi:  150nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322448BDBM322448(US10183938, Compound (R)-201 | (R)-N-(1'-azaspiro[...)
Affinity DataKi:  150nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322380BDBM322380(US10183938, Compound (R)-143 | (R)-N-(2,2-dimethyl...)
Affinity DataKi:  155nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322393BDBM322393(US10183938, Compound (R)-156 | (R)-7-chloro-6-meth...)
Affinity DataKi:  160nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322449BDBM322449(US10183938, Compound (R)-202 | (R)-2-methyl-N-(1'-...)
Affinity DataKi:  160nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322444BDBM322444(US10183938, Compound (R)-197 | (R)-6-fluoro-7-meth...)
Affinity DataKi:  160nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322437BDBM322437(US10183938, Compound (R)-191 | (R)-7-isopropoxy-N-...)
Affinity DataKi:  160nMAssay Description:[3H]BRL 43694 competition binding assay was performed under contract by Cerep Poitiers, France following the methods described in Hope, A. G et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322362BDBM322362(US10183938, Compound (R)-126 | (R)-N-(2,2-dimethyl...)
Affinity DataKi:  170nMAssay Description:[3H]BRL 43694 competition binding assay was performed under contract by Cerep Poitiers, France following the methods described in Hope, A. G et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322382BDBM322382(US10183938, Compound (R)-145 | (R)-N-(2,2-dimethyl...)
Affinity DataKi:  180nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322269BDBM322269(US10183938, Compound (R)-52 | (R)-7-chloro-N-(2,2-...)
Affinity DataKi:  180nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322286BDBM322286(US10183938, Compound 65a | 6-chloro-N-(1''-azaspir...)
Affinity DataKi:  180nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322292BDBM322292(US10183938, Compound 68a | US10183938, Compound 68...)
Affinity DataKi:  180nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322445BDBM322445(US10183938, Compound (R)-198 | (R)-7-cyano-6-methy...)
Affinity DataKi:  190nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322406BDBM322406(US10183938, Compound (R)-165 | (R)-7-cyclopropyl-N...)
Affinity DataKi:  200nMAssay Description:[3H]BRL 43694 competition binding assay was performed under contract by Cerep Poitiers, France following the methods described in Hope, A. G et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322285BDBM322285(US10183938, Compound 64a | 5-fluoro-N-(1'-azaspiro...)
Affinity DataKi:  200nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322399BDBM322399(US10183938, Compound (R)-158 | (R)-7-chloro-6-fluo...)
Affinity DataKi:  200nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322434BDBM322434(US10183938, Compound (R)-188 | (R)-7-(1-methylcycl...)
Affinity DataKi:  200nMAssay Description:[3H]BRL 43694 competition binding assay was performed under contract by Cerep Poitiers, France following the methods described in Hope, A. G et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322436BDBM322436(US10183938, Compound (R)-190 | (R)-7-ethoxy-N-(1'-...)
Affinity DataKi:  200nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322298BDBM322298(US10183938, Compound 71a | US10183938, Compound 71...)
Affinity DataKi:  210nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322437BDBM322437(US10183938, Compound (R)-191 | (R)-7-isopropoxy-N-...)
Affinity DataKi:  220nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322282BDBM322282(US10183938, Compound 61a | 6-fluoro-N-(1'-azaspiro...)
Affinity DataKi:  220nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 322438BDBM322438(US10183938, Compound (R)-192 | (R)-6-chloro-7-meth...)
Affinity DataKi:  220nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

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