Compile Data Set for Download or QSAR
Report error Found 323 Enz. Inhib. hit(s) with all data for entry = 8656
TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411309BDBM411309(N-[4-(4-Fluoro-2-methoxy-phenyl)-pyridin-3-yl]-N-m...)
Affinity DataEC50:  5nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411152BDBM411152(N-[4-(4-Fluoro-2-methoxy-phenyl)-pyridin-3-yl]-N-m...)
Affinity DataEC50:  6nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411070BDBM411070(N-[4-(2-Fluoro-6-methoxy-phenyl)-pyridin-3-yl]-N-m...)
Affinity DataEC50:  8nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411093BDBM411093(N-[4-(2-Chloro-phenyl)-pyridin-3-yl]-N-(2-methoxy-...)
Affinity DataEC50:  8nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411281BDBM411281(N-[4-(2-Cyclobutoxy-phenyl)-pyridin-3-yl]-3-methan...)
Affinity DataEC50:  8nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411036BDBM411036(N-(2-Methoxy-[3,4′]bipyridinyl-3′-yl)-...)
Affinity DataEC50:  9nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411246BDBM411246(N-[4-(2-Cyclopropoxy-phenyl)-pyridin-3-yl]-3-metha...)
Affinity DataEC50:  11nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411326BDBM411326(US10385022, Example 322 | N-Methyl-N-(4-phenyl-pyr...)
Affinity DataEC50:  11nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 410911BDBM410911(N-[4-(2-Methoxy-phenyl)-pyridin-3-yl]-N-methyl-3,5...)
Affinity DataEC50:  11nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411042BDBM411042(N-[4-(4-Fluoro-2-methoxy-phenyl)-pyridin-3-yl]-N-m...)
Affinity DataEC50:  11nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411147BDBM411147(3-Dimethylsulfamoyl-N-[4-(4-fluoro-2-methoxy-pheny...)
Affinity DataEC50:  12nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411199BDBM411199(Methyl 2-(N-(4-(2-fluoro-6-methoxyphenyl)pyridin-3...)
Affinity DataEC50:  13nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411180BDBM411180({(2,6-Bis-trifluoromethyl-pyridine-4-carbonyl)-[4-...)
Affinity DataEC50:  14nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411068BDBM411068(N-[4-(2,6-Difluoro-phenyl)-pyridin-3-yl]-N-methyl-...)
Affinity DataEC50:  14nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 410871BDBM410871(N-[4-(2-Fluoro-phenyl)-pyridin-3-yl]-N-methyl-3,5-...)
Affinity DataEC50:  14nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411308BDBM411308(3-(1,1-Dioxo-thiomorpholine-4-sulfonyl)-N-[4-(4-fl...)
Affinity DataEC50:  15nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411188BDBM411188(N-Methyl-3-nitro-N-(4-o-tolylpyridin-3-yl)-5-(trif...)
Affinity DataEC50:  15nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411209BDBM411209(N-[4-(2-Fluoro-6-methoxy-phenyl)-pyridin-3-yl]-3-m...)
Affinity DataEC50:  17nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411267BDBM411267(3-Methanesulfonyl-N-[4-(2-methoxy-phenyl)-pyridin-...)
Affinity DataEC50:  17nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411307BDBM411307(3-Bromo-N-[4-(4-fluoro-2-methoxy-phenyl)-6-methyl-...)
Affinity DataEC50:  18nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411151BDBM411151(N-[4-(4-Fluoro-2-methoxy-phenyl)-pyridin-3-yl]-N-(...)
Affinity DataEC50:  18nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411157BDBM411157(N-(2,2-Difluoro-ethyl)-N-[4-(4-fluoro-2-methoxy-ph...)
Affinity DataEC50:  19nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411253BDBM411253(3-(Azetidine-1-sulfonyl)-N-[4-(4-fluoro-2-methoxy-...)
Affinity DataEC50:  19nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411135BDBM411135(N-Methyl-N-(4-o-tolyl-pyridin-3-yl)-2,6-bis-triflu...)
Affinity DataEC50:  19nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411260BDBM411260(N-[4-(4-Fluoro-2-methoxy-phenyl)-pyridin-3-yl]-N-m...)
Affinity DataEC50:  20nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411082BDBM411082(N-[4-(2-Chloro-phenyl)-pyridin-3-yl]-N-methyl-3,5-...)
Affinity DataEC50:  21nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411148BDBM411148(N-[4-(4,5-Difluoro-2-methoxy-phenyl)-pyridin-3-yl]...)
Affinity DataEC50:  22nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 410787BDBM410787(N-Methyl-N-(4-o-tolyl-pyridin-3-yl)-3,5-bis-triflu...)
Affinity DataEC50:  22nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411113BDBM411113(3-Chloro-N-methyl-N-(4-o-tolyl-pyridin-3-yl)-5-tri...)
Affinity DataEC50:  22nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411067BDBM411067(N-[4-(2-Fluoro-5-methoxy-phenyl)-pyridin-3-yl]-N-m...)
Affinity DataEC50:  23nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411210BDBM411210(N-[4-(4-Fluoro-2-methoxy-phenyl)-pyridin-3-yl]-2-m...)
Affinity DataEC50:  23nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411242BDBM411242(3-Chloro-5-cyclopropyl-N-[4-(4-fluoro-2-methoxy-ph...)
Affinity DataEC50:  23nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411200BDBM411200(Methyl 2-(N-(4-(2-fluorophenyl)pyridin-3-yl)-2,6-b...)
Affinity DataEC50:  23nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411173BDBM411173(2-Chloro-N-[4-(4-fluoro-2-methoxy-phenyl)-pyridin-...)
Affinity DataEC50:  26nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411062BDBM411062(N-[4-(5-Fluoro-2-methoxy-phenyl)-pyridin-3-yl]-N-m...)
Affinity DataEC50:  26nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411233BDBM411233(N-[4-(2-Fluoro-6-methoxy-phenyl)-pyridin-3-yl]-3-m...)
Affinity DataEC50:  27nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411186BDBM411186(Methyl 2-(N-(2-methoxy-3,4′-bipyridin-3̸...)
Affinity DataEC50:  27nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 410920BDBM410920(N-Methyl-N-[4-(2-trifluoromethoxy-phenyl)-pyridin-...)
Affinity DataEC50:  29nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411132BDBM411132(3-Dimethylsulfamoyl-N-methyl-N-(4-o-tolyl-pyridin-...)
Affinity DataEC50:  29nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411165BDBM411165(N-Cyanomethyl-N-(4-o-tolyl-pyridin-3-yl)-3,5-bis-t...)
Affinity DataEC50:  29nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411149BDBM411149(N-(2-Methoxy-[3,4′]bipyridinyl-3′-yl)-...)
Affinity DataEC50:  30nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411118BDBM411118(3-Methanesulfonyl-N-methyl-N-(4-o-tolyl-pyridin-3-...)
Affinity DataEC50:  30nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411255BDBM411255(N-[4-(4-Fluoro-2-methoxy-phenyl)-pyridin-3-yl]-N-m...)
Affinity DataEC50:  30nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411048BDBM411048(N-(5-Fluoro-2-methoxy-[3,4′]bipyridinyl-3...)
Affinity DataEC50:  30nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411221BDBM411221(N-[4-(4-Fluoro-2-methoxy-phenyl)-pyridin-3-yl]-3-(...)
Affinity DataEC50:  31nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411203BDBM411203(N-Carbamoylmethyl-N-[4-(2-fluoro-6-methoxy-phenyl)...)
Affinity DataEC50:  33nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411278BDBM411278(3-Methanesulfonyl-N-methyl-N-[4-(2-trifluoromethox...)
Affinity DataEC50:  34nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411078BDBM411078(3-Bromo-N-[4-(2-chloro-phenyl)-pyridin-3-yl]-N-met...)
Affinity DataEC50:  34nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 410845BDBM410845(N-[4-(4-Fluoro-2-methoxy-phenyl)-pyridin-3-yl]-3-m...)
Affinity DataEC50:  35nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 411181BDBM411181(N-Carbamoylmethyl-N-[4-(4-fluoro-2-methoxy-phenyl)...)
Affinity DataEC50:  36nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

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