Compile Data Set for Download or QSAR
Report error Found 455 Enz. Inhib. hit(s) with all data for entry = 8927
LigandChemical structure of BindingDB Monomer ID 429751BDBM429751(US10550100, Compound 72 | 5-(3-(4-(4- fluoro-3,5- ...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429750BDBM429750(US10550100, Compound 71 | 5-(3-(4-(4,5- dichloro-2...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429752BDBM429752(US10550100, Compound 73 | 5-(3-(4-(3- chloro-4- fl...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429747BDBM429747(US10550100, Compound 68 | (R)-5-(3-(4- (3,4-dichlo...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429748BDBM429748(US10550100, Compound 69 | (R)-5-(3-(4- (3,4-dichlo...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429745BDBM429745(US10550100, Compound 66 | (R)-5-(3-(4-(3- chloro-5...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429741BDBM429741(US10550100, Compound 62 | 5-(3-(4-(4,5- dichloro-2...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429740BDBM429740(US10550100, Compound 61 | (R)-5-(3-(4- (4,5-dichlo...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429768BDBM429768(US10550100, Compound 88 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429767BDBM429767(US10550100, Compound 87 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429770BDBM429770(US10550100, Compound 90 | (5R)-5-[3-[4- [4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429769BDBM429769(US10550100, Compound 89 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429763BDBM429763(US10550100, Compound 84 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429765BDBM429765(US10550100, Compound 85 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429759BDBM429759(US10550100, Compound 80 | (5R)-5-[3-[4- (3-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429758BDBM429758(US10550100, Compound 79 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429761BDBM429761(US10550100, Compound 82 | (5R)-5-[3-[4- (4-fluoro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429760BDBM429760(US10550100, Compound 81 | (5R)-5-[3-[4- (4-fluoro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429780BDBM429780(US10550100, Compound 104 | 5-[3-[4-(4- chloro-3-et...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429779BDBM429779(US10550100, Compound 103 | 5-[3-[4-(4- chloro-3- f...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429782BDBM429782(US10550100, Compound 106 | (5R)-5-[3-[4- (4-chloro...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429781BDBM429781(US10550100, Compound 105 | (5R)-5-[3-[4- (4-chloro...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429776BDBM429776(US10550100, Compound 100 | (5R)-5-[3-[4- (4-chloro...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429778BDBM429778(US10550100, Compound 102 | 5-[3-[4-(4- chloro-3- f...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429772BDBM429772(US10550100, Compound 96 | (5R)-5-[3-[4- (4,5-dichl...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429797BDBM429797(US10550100, Compound 95 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429774BDBM429774(US10550100, Compound 98 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429773BDBM429773(US10550100, Compound 97 | 5-[3-[4-(4- chloro-2- me...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429795BDBM429795(US10550100, Compound 92 | 5-[3-[4-(4,5- dichloro-2...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429771BDBM429771(US10550100, Compound 93 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429779BDBM429779(US10550100, Compound 103 | 5-[3-[4-(4- chloro-3- f...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID NO: 2) by human ADAMTS-5.For the dose res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429791BDBM429791(US10550100, Compound 115 | (5R)-5-[3-[4- (4-chloro...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429787BDBM429787(US10550100, Compound 111 | 5-[3-[4-(5- chloro-4- f...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429790BDBM429790(US10550100, Compound 114 | 5-[3-[4-(4- chloro-3- m...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429789BDBM429789(US10550100, Compound 113 | 5-[3-[4-(4- chloro-3- m...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429784BDBM429784(US10550100, Compound 108 | 5-[3-[4-(4- chloro-2- m...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429783BDBM429783(US10550100, Compound 107 | 5-[3-[4-(5- chloro-4- f...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429773BDBM429773(US10550100, Compound 97 | 5-[3-[4-(4- chloro-2- me...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429785BDBM429785(US10550100, Compound 109 | 5-[3-[4-(4- chloro-5- f...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429691BDBM429691(US10550100, Compound 24 | 5-(3-(4-(4- chlorophenyl...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429692BDBM429692(US10550100, Compound 25 | 5-(3-(4-(3,5- dichloroph...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

TargetADAMTS5(Rat)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 429696BDBM429696(US10550100, Compound 29 | 5-(3-(4-(3- chlorophenyl...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID NO: 2) by rnADAMTS-5 (1-564-6H).For the d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429689BDBM429689(US10550100, Compound 22 | 5-(3-(4-(4- chloro-3,5- ...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429688BDBM429688(US10550100, Compound 21 | (R)-5-(3-(4-(4- chloro-3...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

TargetADAMTS5(Rat)
Galapagos

US Patent
LigandChemical structure of BindingDB Monomer ID 429695BDBM429695(US10550100, Compound 28 | 5-(3-(4-(3- fluorophenyl...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID NO: 2) by rnADAMTS-5 (1-564-6H).For the d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429715BDBM429715(US10550100, Compound 36 | 5-(3-(4-(4- chloro-3- me...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429716BDBM429716(US10550100, Compound 37 | 5-(3-(4-(4- chloro-5- me...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429726BDBM429726(US10550100, Compound 47 | 5-(3-(4-(4- chloro-3- fl...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429723BDBM429723(US10550100, Compound 44 | 5-(3-(4-(4- chloro-2- me...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429725BDBM429725(US10550100, Compound 46 | (R)-5-(3-(4-(4- chloro-3...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

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