Compile Data Set for Download or QSAR
Report error Found 318 Enz. Inhib. hit(s) with all data for entry = 9350
TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458882BDBM458882(US10759793, Example 34)
Affinity DataIC50: 0.200nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458866BDBM458866(US10759793, Example 19)
Affinity DataIC50: 0.300nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458920BDBM458920(US10759793, Example 66)
Affinity DataIC50: 0.300nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458879BDBM458879(US10759793, Example 31)
Affinity DataIC50: 0.400nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458867BDBM458867(US10759793, Example 20)
Affinity DataIC50: 0.5nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458884BDBM458884(US10759793, Example 36)
Affinity DataIC50: 0.5nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154]()
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458956BDBM458956(US10759793, Example 100)
Affinity DataIC50: 0.5nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458933BDBM458933(US10759793, Example 78)
Affinity DataIC50: 0.5nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458861BDBM458861(US10759793, Example 14)
Affinity DataIC50: 0.5nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458859BDBM458859(US10759793, Example 12)
Affinity DataIC50: 0.5nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458854BDBM458854(US10759793, Example 7)
Affinity DataIC50: 0.5nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458848BDBM458848(US10759793, Example 1)
Affinity DataIC50: 0.5nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458857BDBM458857(US10759793, Example 10)
Affinity DataIC50: 0.5nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458852BDBM458852(US10759793, Example 5)
Affinity DataIC50: 0.5nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458906BDBM458906(US10759793, Example 53)
Affinity DataIC50: 0.5nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458878BDBM458878(US10759793, Example 30)
Affinity DataIC50: 0.600nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458872BDBM458872(US10759793, Example 25)
Affinity DataIC50: 0.600nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458865BDBM458865(US10759793, Example 18)
Affinity DataIC50: 0.600nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458864BDBM458864(US10759793, Example 17)
Affinity DataIC50: 0.600nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458881BDBM458881(US10759793, Example 33)
Affinity DataIC50: 0.600nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458880BDBM458880(US10759793, Example 32)
Affinity DataIC50: 0.600nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [795-1124](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458857BDBM458857(US10759793, Example 10)
Affinity DataIC50: 0.700nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458856BDBM458856(US10759793, Example 9)
Affinity DataIC50: 0.700nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458855BDBM458855(US10759793, Example 8)
Affinity DataIC50: 0.700nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458853BDBM458853(US10759793, Example 6)
Affinity DataIC50: 0.700nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458869BDBM458869(US10759793, Example 22)
Affinity DataIC50: 0.700nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458863BDBM458863(US10759793, Example 16)
Affinity DataIC50: 0.700nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458875BDBM458875(US10759793, Example 27)
Affinity DataIC50: 0.700nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458891BDBM458891(US10759793, Example 43)
Affinity DataIC50: 0.700nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458888BDBM458888(US10759793, Example 40)
Affinity DataIC50: 0.800nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458850BDBM458850(US10759793, Example 3)
Affinity DataIC50: 0.800nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458876BDBM458876(US10759793, Example 28)
Affinity DataIC50: 0.800nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458887BDBM458887(US10759793, Example 39)
Affinity DataIC50: 0.800nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [795-1124](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458962BDBM458962(US10759793, Example 106)
Affinity DataIC50: 1nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154]()
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458867BDBM458867(US10759793, Example 20)
Affinity DataIC50: 1nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458916BDBM458916(US10759793, Example 62)
Affinity DataIC50: 1nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [795-1124](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458867BDBM458867(US10759793, Example 20)
Affinity DataIC50: 1nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154]()
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458959BDBM458959(US10759793, Example 103)
Affinity DataIC50: 1nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [795-1124](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458960BDBM458960(US10759793, Example 104)
Affinity DataIC50: 1nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154]()
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458865BDBM458865(US10759793, Example 18)
Affinity DataIC50: 1nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [795-1124](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458959BDBM458959(US10759793, Example 103)
Affinity DataIC50: 1nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458959BDBM458959(US10759793, Example 103)
Affinity DataIC50: 1nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [795-1124](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458864BDBM458864(US10759793, Example 17)
Affinity DataIC50: 1nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [850-1154]()
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458958BDBM458958(US10759793, Example 102)
Affinity DataIC50: 1nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [795-1124](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458957BDBM458957(US10759793, Example 101)
Affinity DataIC50: 1nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458957BDBM458957(US10759793, Example 101)
Affinity DataIC50: 1nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [795-1124](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458863BDBM458863(US10759793, Example 16)
Affinity DataIC50: 1nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458922BDBM458922(US10759793, Example 68)
Affinity DataIC50: 1nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458871BDBM458871(US10759793, Example 24)
Affinity DataIC50: 1nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Almirall

US Patent
LigandChemical structure of BindingDB Monomer ID 458870BDBM458870(US10759793, Example 23)
Affinity DataIC50: 1nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

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