Compile Data Set for Download or QSAR
Report error Found 136 Enz. Inhib. hit(s) with all data for entry = 11370
TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610463BDBM610463(US10774086, Example 14 | N-(4-(2-Methylmorpholino)...)
Affinity DataIC50: 0.0900nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610453BDBM610453(US10774086, Example 4 | 2-Phenyl-N-(4-(2,2,2-trifl...)
Affinity DataIC50: 0.100nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610459BDBM610459(US10774086, Example 10 | N-(4-(4-Cyanopiperidin-1-...)
Affinity DataIC50: 0.100nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610486BDBM610486(US10774086, Example 34 | 2-(Cyclohex-1-en-1-yl)-N-...)
Affinity DataIC50: 0.100nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610460BDBM610460(US10774086, Example 11 | N-(4-(4-Fluoropiperidin-1...)
Affinity DataIC50: 0.200nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610459BDBM610459(US10774086, Example 10 | N-(4-(4-Cyanopiperidin-1-...)
Affinity DataIC50: 0.200nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610473BDBM610473(US10774086, Example 21 | N-(6-Fluoro-4-morpholinop...)
Affinity DataIC50: 0.200nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610461BDBM610461(US10774086, Example 12 | N-(4-(4,4-Difluoropiperid...)
Affinity DataIC50: 0.200nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610462BDBM610462(US10774086, Example 13 | N-(4-Morpholinopyridin-3-...)
Affinity DataIC50: 0.200nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610458BDBM610458(US10774086, Example 9 | 2-Phenyl-N-(4-(piperidin-1...)
Affinity DataIC50: 0.200nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610463BDBM610463(US10774086, Example 14 | N-(4-(2-Methylmorpholino)...)
Affinity DataIC50: 0.200nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610483BDBM610483(US10774086, Example 31 | 2-Cyclopropyl-N-(4-(4,4-d...)
Affinity DataIC50: 0.200nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610477BDBM610477(US10774086, Example 25 | N-(4-Morpholinopyridin-3-...)
Affinity DataIC50: 0.200nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610463BDBM610463(US10774086, Example 14 | N-(4-(2-Methylmorpholino)...)
Affinity DataIC50: 0.300nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610460BDBM610460(US10774086, Example 11 | N-(4-(4-Fluoropiperidin-1...)
Affinity DataIC50: 0.300nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610453BDBM610453(US10774086, Example 4 | 2-Phenyl-N-(4-(2,2,2-trifl...)
Affinity DataIC50: 0.300nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610469BDBM610469(US10774086, Example 18 | (S) N-(4-(3-Methylmorphol...)
Affinity DataIC50: 0.300nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610469BDBM610469(US10774086, Example 18 | (S) N-(4-(3-Methylmorphol...)
Affinity DataIC50: 0.300nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610457BDBM610457(US10774086, Example 8 | N-(4-(4-Cyanophenyl)pyridi...)
Affinity DataIC50: 0.300nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610486BDBM610486(US10774086, Example 34 | 2-(Cyclohex-1-en-1-yl)-N-...)
Affinity DataIC50: 0.400nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610461BDBM610461(US10774086, Example 12 | N-(4-(4,4-Difluoropiperid...)
Affinity DataIC50: 0.400nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610454BDBM610454(US10774086, Example 5 | N-(4-(Methylsulfonyl)pyrid...)
Affinity DataIC50: 0.400nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610482BDBM610482(US10774086, Example 30 | 2-Cyclopropyl-N-(4-(4-flu...)
Affinity DataIC50: 0.400nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610476BDBM610476(US10774086, Example 24 | 2-(2-Methoxyphenyl)-N-(4-...)
Affinity DataIC50: 0.400nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610462BDBM610462(US10774086, Example 13 | N-(4-Morpholinopyridin-3-...)
Affinity DataIC50: 0.400nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610452BDBM610452(US10774086, Example 3 | N-(4-Isopropoxypyridin-3-y...)
Affinity DataIC50: 0.400nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610483BDBM610483(US10774086, Example 31 | 2-Cyclopropyl-N-(4-(4,4-d...)
Affinity DataIC50: 0.400nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610488BDBM610488(US10774086, Example 36 | N-(4-Morpholinopyridin-3-...)
Affinity DataIC50: 0.400nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610463BDBM610463(US10774086, Example 14 | N-(4-(2-Methylmorpholino)...)
Affinity DataIC50: 0.400nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610475BDBM610475(US10774086, Example 23 | N-(4-(4,4-Difluoropiperid...)
Affinity DataIC50: 0.600nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610456BDBM610456(US10774086, Example 7 | N-(4-(4-Fluorophenyl)pyrid...)
Affinity DataIC50: 0.600nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610476BDBM610476(US10774086, Example 24 | 2-(2-Methoxyphenyl)-N-(4-...)
Affinity DataIC50: 0.600nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610473BDBM610473(US10774086, Example 21 | N-(6-Fluoro-4-morpholinop...)
Affinity DataIC50: 0.600nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610478BDBM610478(US10774086, Example 26 | N-(4-(2-Methylmorpholino)...)
Affinity DataIC50: 0.600nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610472BDBM610472(BDBM610474 | N-(4-(4,4-Difluoropiperidin-1-yl)-6-f...)
Affinity DataIC50: 0.600nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610452BDBM610452(US10774086, Example 3 | N-(4-Isopropoxypyridin-3-y...)
Affinity DataIC50: 0.700nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610463BDBM610463(US10774086, Example 14 | N-(4-(2-Methylmorpholino)...)
Affinity DataIC50: 0.75nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610463BDBM610463(US10774086, Example 14 | N-(4-(2-Methylmorpholino)...)
Affinity DataIC50: 0.800nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610484BDBM610484(US10774086, Example 32 | 2-Cyclopropyl-N-(4-(2-met...)
Affinity DataIC50: 0.800nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610475BDBM610475(US10774086, Example 23 | N-(4-(4,4-Difluoropiperid...)
Affinity DataIC50: 0.800nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610451BDBM610451(US10774086, Example 2 | N-(4-Methylpyridin-3-yl)-2...)
Affinity DataIC50: 0.800nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610477BDBM610477(US10774086, Example 25 | N-(4-Morpholinopyridin-3-...)
Affinity DataIC50: 0.800nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610490BDBM610490(US10774086, Example 38 | 2-Phenyl-N-(4-(2,2,2-trif...)
Affinity DataIC50: 1nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610468BDBM610468(US10774086, Example 17 | (R) N-(4-(3-Methylmorphol...)
Affinity DataIC50: 1nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610487BDBM610487(US10774086, Example 35 | 2-(Cyclohex-1-en-1-yl)-N-...)
Affinity DataIC50: 1nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610489BDBM610489(US10774086, Example 37 | N-(4-Ethoxypyrimidin-5-yl...)
Affinity DataIC50: 1nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610496BDBM610496(US10774086, Example 43 | 3-((Cyclopropylmethyl)ami...)
Affinity DataIC50: 1.10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610455BDBM610455(US10774086, Example 6 | 2-Phenyl-N-(4-phenylpyridi...)
Affinity DataIC50: 1.10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610457BDBM610457(US10774086, Example 8 | N-(4-(4-Cyanophenyl)pyridi...)
Affinity DataIC50: 1.10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 610458BDBM610458(US10774086, Example 9 | 2-Phenyl-N-(4-(piperidin-1...)
Affinity DataIC50: 1.10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

Displayed 1 to 50 (of 136 total ) | Next | Last >>
Jump to: