Compile Data Set for Download or QSAR
Report error Found 140 Enz. Inhib. hit(s) with all data for entry = 9392
TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392540BDBM392540(N4-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-(...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392541BDBM392541(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-3-(a...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392538BDBM392538(4-amino-N-((6-amino-2,4- dimethylpyridin-3-yl)meth...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392539BDBM392539(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392536BDBM392536(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392537BDBM392537(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392534BDBM392534(5-amino-N-((6-amino-2,4- dimethylpyridin-3-yl)meth...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392535BDBM392535(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-2-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392532BDBM392532(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392533BDBM392533(4-acetamido-N-((6-amino-2,4- dimethylpyridin-3-yl)...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392530BDBM392530(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392531BDBM392531(3-amino-N-((6-amino-2,4- dimethylpyridin-3-yl)meth...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392527BDBM392527(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392525BDBM392525(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392526BDBM392526(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392552BDBM392552(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392553BDBM392553(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392550BDBM392550(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392551BDBM392551(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-2-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392548BDBM392548(4-amino-N-((6-amino-2,4- dimethylpyridin-3-yl)meth...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392549BDBM392549(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392546BDBM392546(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-7-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392544BDBM392544(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-5-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392545BDBM392545(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-5-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392542BDBM392542(2-amino-N-((6-amino-2,4- dimethylpyridin-3-yl)meth...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392543BDBM392543(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-2-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392572BDBM392572(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392573BDBM392573(N-((1-aminoisoquinolin-6-yl)methyl)- 1-((3-chloro-...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392570BDBM392570(N-((3-chloro-1H-pyrrolo[2,3- b]pyridin-5-yl)methyl...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392568BDBM392568(N-((1-aminoisoquinolin-6-yl)methyl)- 1-((3-chloro-...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392566BDBM392566(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392567BDBM392567(N-((3-chloro-6-fluoro-1H-indol-5- yl)methyl)-1-((3...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392563BDBM392563(N-((1-aminoisoquinolin-6-yl)methyl)- 1-((3-chloroq...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392588BDBM392588(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-5-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392589BDBM392589(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392586BDBM392586(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-3-cy...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392587BDBM392587(N-((6-amino-2-methylpyridin-3- yl)methyl)-3-cyano-...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392585BDBM392585(6-((4-(((6-amino-2,4-dimethylpyridin- 3-yl)methyl)...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392582BDBM392582(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392581BDBM392581(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392578BDBM392578(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-3-cy...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392579BDBM392579(N-((6-amino-2-methylpyridin-3- yl)methyl)-3-cyano-...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392576BDBM392576(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-3-cy...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392574BDBM392574(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392575BDBM392575(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-3-cy...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392604BDBM392604(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392605BDBM392605(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392602BDBM392602(US10301284, Example 114 | N-((6-amino-2,4-dimethyl...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392603BDBM392603(N-((6-amino-2-methylpyridin-3- yl)methyl)-2-((3-ch...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 392600BDBM392600(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-2-((...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

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