Compile Data Set for Download or QSAR
Report error Found 217 Enz. Inhib. hit(s) with all data for entry = 9442
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466559BDBM466559(US10800755, Example 14 | US11014905, Example 14)
Affinity DataIC50: 0.100nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466556BDBM466556(4,4-Difluoro-N-{2-[6-(trifluoromethyl)-3′,6&...)
Affinity DataIC50: 0.200nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466577BDBM466577(2,2-Dimethyl-N-{2-[6-(trifluoromethyl)-3′,6&...)
Affinity DataIC50: 0.300nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466547BDBM466547(US10800755, Example 4 | US11014905, Example 4)
Affinity DataIC50: 0.400nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466575BDBM466575(N-[2-(6-Methyl-3′,6′-dihydro[2,4′...)
Affinity DataIC50: 0.400nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466535BDBM466535(4,4-Difluoro-N-(2-{4-[6-(trifluoromethyl)pyridin-2...)
Affinity DataIC50: 0.400nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466565BDBM466565(US10800755, Example 19 | US11014905, Example 19)
Affinity DataIC50: 0.800nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466553BDBM466553(US10800755, Example 9 | US11014905, Example 9)
Affinity DataIC50: 1.10nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466557BDBM466557(US10800755, Example 13 | US11014905, Example 13)
Affinity DataIC50: 1.10nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466576BDBM466576(2,2-Dimethyl-N-[2-(6-methyl-3′,6′-dihy...)
Affinity DataIC50: 1.40nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466552BDBM466552(N-{2-[4-(6-Methylpyridin-2-yl)piperidin-1-yl]ethyl...)
Affinity DataIC50: 1.40nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466554BDBM466554(US10800755, Example 10 | US11014905, Example 10)
Affinity DataIC50: 1.40nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466555BDBM466555(US10800755, Example 11 | US11014905, Example 11)
Affinity DataIC50: 2.10nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetD(4) dopamine receptor(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466577BDBM466577(2,2-Dimethyl-N-{2-[6-(trifluoromethyl)-3′,6&...)
Affinity DataIC50: 2.90nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetD(4) dopamine receptor(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466559BDBM466559(US10800755, Example 14 | US11014905, Example 14)
Affinity DataIC50: 3nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetD(4) dopamine receptor(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466556BDBM466556(4,4-Difluoro-N-{2-[6-(trifluoromethyl)-3′,6&...)
Affinity DataIC50: 4.5nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466561BDBM466561(N-{2-[6-(Trifluoromethyl)-3′,6′-dihydr...)
Affinity DataIC50: 6nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466566BDBM466566(US10800755, Example 20)
Affinity DataIC50: 6.80nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetD(4) dopamine receptor(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466578BDBM466578(US10800755, Example 32 | US11014905, Example 32)
Affinity DataEC50:  7nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466545BDBM466545(US10800755, Example 3 | US11014905, Example 3)
Affinity DataIC50: 7.10nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetD(4) dopamine receptor(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466553BDBM466553(US10800755, Example 9 | US11014905, Example 9)
Affinity DataIC50: 8nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetD(4) dopamine receptor(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466565BDBM466565(US10800755, Example 19 | US11014905, Example 19)
Affinity DataIC50: 8nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetD(4) dopamine receptor(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466565BDBM466565(US10800755, Example 19 | US11014905, Example 19)
Affinity DataEC50:  9nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466556BDBM466556(4,4-Difluoro-N-{2-[6-(trifluoromethyl)-3′,6&...)
Affinity DataEC50: <10nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetD(4) dopamine receptor(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466554BDBM466554(US10800755, Example 10 | US11014905, Example 10)
Affinity DataEC50:  10nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetD(4) dopamine receptor(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466553BDBM466553(US10800755, Example 9 | US11014905, Example 9)
Affinity DataEC50: <10nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466554BDBM466554(US10800755, Example 10 | US11014905, Example 10)
Affinity DataEC50:  10nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466580BDBM466580(US10800755, Example 34 | US11014905, Example 34)
Affinity DataIC50: 10nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466553BDBM466553(US10800755, Example 9 | US11014905, Example 9)
Affinity DataEC50: <10nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetD(4) dopamine receptor(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466551BDBM466551(US10800755, Example 7)
Affinity DataEC50: <10nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466552BDBM466552(N-{2-[4-(6-Methylpyridin-2-yl)piperidin-1-yl]ethyl...)
Affinity DataEC50: <10nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetD(4) dopamine receptor(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466550BDBM466550(US10800755, Example 6 | US11014905, Example 6)
Affinity DataEC50: <10nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466551BDBM466551(US10800755, Example 7)
Affinity DataEC50: <10nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466547BDBM466547(US10800755, Example 4 | US11014905, Example 4)
Affinity DataEC50: <10nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466565BDBM466565(US10800755, Example 19 | US11014905, Example 19)
Affinity DataEC50: <10nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466535BDBM466535(4,4-Difluoro-N-(2-{4-[6-(trifluoromethyl)pyridin-2...)
Affinity DataEC50: <10nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetD(4) dopamine receptor(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466577BDBM466577(2,2-Dimethyl-N-{2-[6-(trifluoromethyl)-3′,6&...)
Affinity DataEC50: <10nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetD(4) dopamine receptor(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466559BDBM466559(US10800755, Example 14 | US11014905, Example 14)
Affinity DataEC50: <10nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetD(4) dopamine receptor(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466576BDBM466576(2,2-Dimethyl-N-[2-(6-methyl-3′,6′-dihy...)
Affinity DataEC50: <10nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetD(4) dopamine receptor(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466584BDBM466584(N-(2-{4-[6-(Dimethylamino)pyridin-2-yl]piperidin-1...)
Affinity DataIC50: 10nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetD(4) dopamine receptor(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466557BDBM466557(US10800755, Example 13 | US11014905, Example 13)
Affinity DataEC50: <10nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466559BDBM466559(US10800755, Example 14 | US11014905, Example 14)
Affinity DataEC50: <10nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466557BDBM466557(US10800755, Example 13 | US11014905, Example 13)
Affinity DataEC50: <10nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466575BDBM466575(N-[2-(6-Methyl-3′,6′-dihydro[2,4′...)
Affinity DataEC50: <10nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466540BDBM466540(US10800755, Example 2)
Affinity DataIC50: 11nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetD(4) dopamine receptor(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466535BDBM466535(4,4-Difluoro-N-(2-{4-[6-(trifluoromethyl)pyridin-2...)
Affinity DataIC50: 11nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetD(4) dopamine receptor(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466535BDBM466535(4,4-Difluoro-N-(2-{4-[6-(trifluoromethyl)pyridin-2...)
Affinity DataEC50:  11.9nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466560BDBM466560(US10800755, Example 15 | US11014905, Example 15)
Affinity DataIC50: 13nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetD(4) dopamine receptor(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466579BDBM466579(US10800755, Example 33 | US11014905, Example 33)
Affinity DataEC50:  13nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 466551BDBM466551(US10800755, Example 7)
Affinity DataIC50: 13nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

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