Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 9632
TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 391716BDBM391716(US10300056, Example 1 | N-[(2R)-3-(7-methyl-1H- | ...)
Affinity DataKi:  0.0200nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 391727BDBM391727(US10300056, Example 12 | N-[(2R)-1-({(2S)-3-{1-[2-...)
Affinity DataKi:  0.0250nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 391726BDBM391726(US10300056, Example 11 | N-[(2R)-3-(7-methyl-1H- |...)
Affinity DataKi:  0.0320nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 391722BDBM391722(US10300056, Example 7 | N-[(2R)-1-({(2S)-3-(1- | U...)
Affinity DataKi:  0.0400nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 391719BDBM391719(US10300056, Example 4 | N-[(2R)-3-(7-methyl-1H- | ...)
Affinity DataKi:  0.0400nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 391723BDBM391723(US10300056, Example 8 | 3,5-dibromo-Nalpha-{[4-(2-...)
Affinity DataKi:  0.0400nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 391720BDBM391720(US10300056, Example 5 | 3,5-dibromo-Nalpha-{[4-(2-...)
Affinity DataKi:  0.0630nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 391725BDBM391725(US10300056, Example 10 | N-[(2R)-3-(7-methyl-1H- |...)
Affinity DataKi:  0.0630nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 391718BDBM391718(US10300056, Example 3 | N-[(2R)-3-(7-methyl-1H- | ...)
Affinity DataKi:  0.0790nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 391729BDBM391729(US10300056, Example 14 | 3,5-dibromo-Nalpha-[(2'-o...)
Affinity DataKi:  0.0790nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 391724BDBM391724(US10300056, Example 9 | 3,5-dibromo-Nalpha-{[4-(2-...)
Affinity DataKi:  0.0790nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 391721BDBM391721(US10300056, Example 6 | N-[(2R)-3-(7-methyl-1H- | ...)
Affinity DataKi:  0.100nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 391717BDBM391717(US10300056, Example 2 | tert-butyl 4-{(2S)-2- | US...)
Affinity DataKi:  0.100nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 391728BDBM391728(US10300056, Example 13 | 3-(4-{(2S)-2-{[(2R)-3-(7-...)
Affinity DataKi:  0.100nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent