Compile Data Set for Download or QSAR
Report error Found 140 Enz. Inhib. hit(s) with all data for entry = 10120
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514696BDBM514696((S)-N-(3-(2-((1- (hydroxymethyl)cyclopropyl)amino)...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514697BDBM514697((S)-N-(3-(2-(((1R,3S)-3-hydroxy-1-methylcyclobutyl...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514697BDBM514697((S)-N-(3-(2-(((1R,3S)-3-hydroxy-1-methylcyclobutyl...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514699BDBM514699((S)-N-(3-(2-(((2R,3R)-3-hydroxybutan-2- yl)amino)-...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514700BDBM514700((3S)-N-(3-(2-((1-cyanopropan-2- yl)amino)-6-morpho...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514701BDBM514701(US11098031, Example 64 | (S)-N-(3-(2-(((1S,4R)-4-h...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514701BDBM514701(US11098031, Example 64 | (S)-N-(3-(2-(((1S,4R)-4-h...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514703BDBM514703((S)-N-(3-(2-((1,3-dihydroxypropan-2- yl)amino)-6-m...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514704BDBM514704((S)-N-(3-(2-amino-6-morpholinopyridin- 4-yl)-4-met...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514705BDBM514705((S)-N-(4-methyl-3-(2-(methylamino)-6- morpholinopy...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514706BDBM514706((S)-N-(3-(2-(((R)-1-hydroxypropan-2- yl)amino)-6-(...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514707BDBM514707((S)-N-(3-(2-acetamido-6- morpholinopyridin-4-yl)-4...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514708BDBM514708((S)-N-(3-(3-fluoro-2-(((R)-1- hydroxypropan-2-yl)a...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514709BDBM514709((S)-N-(3-(3-fluoro-6-(((R)-1- hydroxypropan-2-yl)a...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514710BDBM514710((S)-N-(3-(2-(trans-3-hydroxy-2-methylazetidin-1-yl...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514710BDBM514710((S)-N-(3-(2-(trans-3-hydroxy-2-methylazetidin-1-yl...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514680BDBM514680((S)-N-(4-methyl-3-(2-morpholino-6- (oxetan-3-ylami...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514681BDBM514681((S)-N-(4-methyl-3-(2-morpholino-6- (((R)-tetrahydr...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514682BDBM514682((S)-N-(4-methyl-3-(2-morpholino-6- (((S)-tetrahydr...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514683BDBM514683((S)-N-(4-methyl-3-(2-morpholino-6- (((R)-tetrahydr...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514684BDBM514684((S)-N-(4-methyl-3-(2-morpholino-6- ((tetrahydro-2H...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514685BDBM514685((S)-N-(3-(2-(((1S,3R)-3- hydroxycyclobutyl)amino)-...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514686BDBM514686((S)-N-(3-(2-(((1R,3S)-3- hydroxycyclobutyl)amino)-...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514687BDBM514687((S)-N-(3-(2-(((R)-1-hydroxybutan-2- yl)amino)-6-mo...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514688BDBM514688((S)-N-(3-(2-(((R)-1-methoxypropan-2- yl)amino)-6-m...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514689BDBM514689((S)-N-(3-(2-(((S)-2- methoxypropyl)amino)-6- morph...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514690BDBM514690((S)-N-(4-methyl-3-(2-morpholino-6- (((S)-tetrahydr...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514691BDBM514691((3S)-N-(4-methyl-3-(2-((3- methyltetrahydrofuran-3...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514692BDBM514692((S)-N-(3-(2-((1- (hydroxymethyl)cyclobutyl)amino)-...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514693BDBM514693((S)-N-(3-(2-((3-(hydroxymethyl)oxetan- 3-yl)amino)...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514694BDBM514694((S)-N-(4-methyl-3-(2-((3-methyloxetan- 3-yl)amino)...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514695BDBM514695((S)-N-(4-methyl-3-(2-((4- methyltetrahydro-2H-pyra...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514728BDBM514728(US11098031, Example 91 | (S)-N-(3-(6-(((R)-2-hydro...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514728BDBM514728(US11098031, Example 91 | (S)-N-(3-(6-(((R)-2-hydro...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514731BDBM514731((S)-N-(3-(6-(((S)-2- hydroxypropyl)amino)-2- morph...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514732BDBM514732((S)-N-(3-(6-((2-hydroxyethyl)amino)-2- morpholinop...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514733BDBM514733((S)-N-(3-(6-(((S)-1-hydroxypropan-2- yl)amino)-2-m...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514734BDBM514734((S)-N-(3-(6-((2-hydroxy-2- methylpropyl)amino)-2- ...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514735BDBM514735((S)-N-(3-(2-((2-hydroxyethyl)amino)-6- morpholinop...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514736BDBM514736((S)-N-(3-(2-(((R)-1-hydroxypropan-2- yl)amino)-6-m...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514737BDBM514737((S)-N-(3-(2-((2-hydroxy-2- methylpropyl)amino)-6- ...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514738BDBM514738((S)-N-(3-(6-(((R)-1-hydroxypropan-2- yl)amino)-2-m...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514739BDBM514739((S)-N-(3-(2-(((S)-1-hydroxypropan-2- yl)amino)-6-m...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514740BDBM514740(US11098031, Example 103 | (R)-N-(3-(2-((S)-3-hydro...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514740BDBM514740(US11098031, Example 103 | (R)-N-(3-(2-((S)-3-hydro...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514742BDBM514742((S)-N-(3-(2-(((S)-2- hydroxypropyl)amino)-6- morph...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514743BDBM514743((3S)-N-(3-[2-[(3R)-3-aminopyrrolidin-1- yl]-6-(mor...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514712BDBM514712((S)-N-(4-methyl-3-(2-morpholino-6- (((S)-1,1,1-tri...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514713BDBM514713((S)-N-(3-(2-(2-hydroxy-2- methylpropanamido)-6- mo...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 514714BDBM514714((S)-N-(2-fluoro-5-(2-(((R)-1- hydroxypropan-2-yl)a...)
Affinity DataIC50: 10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

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