Compile Data Set for Download or QSAR
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 10393
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532540BDBM532540(US11214563, Example 1 | 1-[6-[3-(Difluoromethyl)-4...)
Affinity DataIC50: 22nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532560BDBM532560(US11214563, Example 21 | 2-[6-(2,4-Difluoro-3-meth...)
Affinity DataIC50: 34nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532551BDBM532551(US11214563, Example 12 | 2-[6-[4-Chloro-3-(difluor...)
Affinity DataIC50: 36nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532563BDBM532563(US11214563, Example 24 | 1-(Azetidin-1-yl)-2-[6-[3...)
Affinity DataIC50: 37nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532571BDBM532571(US11214563, Example 32 | 2-[6-[3-(Difluoromethyl)-...)
Affinity DataIC50: 37nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532549BDBM532549(US11214563, Example 10 | 2-[6-[3-(Difluoromethyl)-...)
Affinity DataIC50: 42nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532550BDBM532550(US11214563, Example 11 | 2-[6-[3-(Difluoromethyl)-...)
Affinity DataIC50: 59nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532567BDBM532567(US11214563, Example 28 | 1-(Azetidin-1-yl)-2-[6-[3...)
Affinity DataIC50: 59nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532557BDBM532557(US11214563, Example 18 | 2-[6-[4-Chloro-3-(difluor...)
Affinity DataIC50: 64nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532564BDBM532564(US11214563, Example 25 | 1-(Azetidin-1-yl)-2-[6-[3...)
Affinity DataIC50: 65nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532568BDBM532568(US11214563, Example 29 | 1-(Azetidin-1-yl)-2-[6-[4...)
Affinity DataIC50: 69nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532555BDBM532555(US11214563, Example 16 | 2-[6-[3-(Difluoromethoxy)...)
Affinity DataIC50: 72nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532572BDBM532572(US11214563, Example 33 | 2-[6-[3-(Difluoromethyl)-...)
Affinity DataIC50: 77nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532581BDBM532581(US11214563, Example 42 | 6-[3-(Difluoromethyl)-4-f...)
Affinity DataIC50: 79nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532541BDBM532541(US11214563, Example 2 | 2-[6-[4-Chloro-3-(difluoro...)
Affinity DataIC50: 81nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532576BDBM532576(US11214563, Example 37 | 2-[6-[3-(Difluoromethoxy)...)
Affinity DataIC50: 92nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532546BDBM532546(US11214563, Example 7 | 2-[6-(4-Fluoro-3-methyl-ph...)
Affinity DataIC50: 117nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532569BDBM532569(US11214563, Example 30 | 2-[6-[3-(Difluoromethyl)-...)
Affinity DataIC50: 122nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532566BDBM532566(US11214563, Example 27 | 1-(Azetidin-1-yl)-2-[6-[3...)
Affinity DataIC50: 126nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532547BDBM532547(US11214563, Example 8 | 2-[6-(4-Chloro-3-methyl-ph...)
Affinity DataIC50: 134nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532565BDBM532565(US11214563, Example 26 | 1-(Azetidin-1-yl)-2-[6-[4...)
Affinity DataIC50: 140nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532552BDBM532552(US11214563, Example 13 | 2-[6-[3-(1,1-Difluoroethy...)
Affinity DataIC50: 146nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532553BDBM532553(US11214563, Example 14 | 2-[6-[4-Chloro-3-(1,1-dif...)
Affinity DataIC50: 149nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532579BDBM532579(US11214563, Example 40 | 2-[[6-[3-(Difluoromethyl)...)
Affinity DataIC50: 158nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532578BDBM532578(US11214563, Example 39 | 2-[[6-[3-(Difluoromethyl)...)
Affinity DataIC50: 162nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532583BDBM532583(US11214563, Example 44 | 6-[3-(Difluoromethyl)-4-f...)
Affinity DataIC50: 165nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532570BDBM532570(US11214563, Example 31 | 2-[6-[3-(Difluoromethyl)-...)
Affinity DataIC50: 196nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532574BDBM532574(US11214563, Example 35 | 2-[6-[4-Chloro-3-(1,1-dif...)
Affinity DataIC50: 212nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532582BDBM532582(US11214563, Example 43 | 1-[(5-Chloro-3-pyridyl)me...)
Affinity DataIC50: 250nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532575BDBM532575(US11214563, Example 36 | 2-[6-[3-(Difluoromethoxy)...)
Affinity DataIC50: 251nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532554BDBM532554(US11214563, Example 15 | 2-[6-[4-Chloro-3-(trifluo...)
Affinity DataIC50: 272nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532586BDBM532586(US11214563, Example 47 | 1-[(5-Chloro-3-pyridyl)me...)
Affinity DataIC50: 284nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532584BDBM532584(US11214563, Example 45 | 5-[[6-[3-(Difluoromethyl)...)
Affinity DataIC50: 285nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532580BDBM532580(US11214563, Example 41 | 5-[[6-[3-(Difluoromethyl)...)
Affinity DataIC50: 337nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532573BDBM532573(US11214563, Example 34 | 2-[6-[4-Chloro-3-(1,1-dif...)
Affinity DataIC50: 408nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532543BDBM532543(US11214563, Example 4 | N,N-Dimethyl-2-[6-(m-tolyl...)
Affinity DataIC50: 410nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532561BDBM532561(US11214563, Example 22 | N,N-Dimethyl-2-[6-(3,4,5-...)
Affinity DataIC50: 489nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532542BDBM532542(US11214563, Example 3 | N,N-Dimethyl-2-[6-[5-(trif...)
Affinity DataIC50: 581nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532548BDBM532548(US11214563, Example 9 | 2-[6-(3-Chloro-4-methoxy-p...)
Affinity DataIC50: 584nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532585BDBM532585(US11214563, Example 46 | 5-[[6-[3-(Difluoromethyl)...)
Affinity DataIC50: 709nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532544BDBM532544(US11214563, Example 5 | 2-[6-(4-Chloro-3-fluoro-ph...)
Affinity DataIC50: 827nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532556BDBM532556(US11214563, Example 17 | 2-[6-[4-(Difluoromethoxy)...)
Affinity DataIC50: 859nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532559BDBM532559(US11214563, Example 20 | 2-[6-(3,5-Difluoro-4-meth...)
Affinity DataIC50: 907nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532545BDBM532545(US11214563, Example 6 | 2-[6-(3-Fluoro-4-methyl-ph...)
Affinity DataIC50: 916nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532562BDBM532562(US11214563, Example 23 | N,N-Dimethyl-2-[6-(2,3,4-...)
Affinity DataIC50: 962nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532558BDBM532558(US11214563, Example 19 | 2-[6-[3-Chloro-4-(trifluo...)
Affinity DataIC50: 1.04E+3nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532577BDBM532577(US11214563, Example 38 | 2-[6-[4-Chloro-3-(1,1-dif...)
Affinity DataIC50: 1.06E+3nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532588BDBM532588(US11214563, Example 49 | N,N-Dimethyl-2-(6-(4-(tri...)
Affinity DataIC50: 2.74E+3nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532587BDBM532587(US11214563, Example 48 | 2-(6-(4-Chloro-2-fluoroph...)
Affinity DataIC50: 2.81E+3nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 532590BDBM532590(US11214563, Example 51 | 5-((6-(3-(Difluoromethoxy...)
Affinity DataIC50: 3.00E+3nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

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