Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 10494
TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541356BDBM541356(US11267803, Example 4)
Affinity DataIC50: 5.62nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541388BDBM541388(US11267803, Example 36)
Affinity DataIC50: 6.65nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541357BDBM541357(US11267803, Example 5)
Affinity DataIC50: 9.08nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541363BDBM541363(US11267803, Example 11)
Affinity DataIC50: 9.82nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541389BDBM541389(US11267803, Example 37)
Affinity DataIC50: 10.4nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541400BDBM541400(US11267803, Example 48)
Affinity DataIC50: 11nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541360BDBM541360(US11267803, Example 8)
Affinity DataIC50: 12.5nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541376BDBM541376(US11267803, Example 24)
Affinity DataIC50: 13.8nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541366BDBM541366(US11267803, Example 14)
Affinity DataIC50: 15.6nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541365BDBM541365(US11267803, Example 13)
Affinity DataIC50: 17.2nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541362BDBM541362(US11267803, Example 10)
Affinity DataIC50: 18.1nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541369BDBM541369(US11267803, Example 17)
Affinity DataIC50: 20.1nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541378BDBM541378(US11267803, Example 26)
Affinity DataIC50: 21.6nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541396BDBM541396(US11267803, Example 44)
Affinity DataIC50: 22.3nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541370BDBM541370(US11267803, Example 18)
Affinity DataIC50: 24.4nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541392BDBM541392(US11267803, Example 40)
Affinity DataIC50: 25.2nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541391BDBM541391(US11267803, Example 39)
Affinity DataIC50: 30.5nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541377BDBM541377(US11267803, Example 25)
Affinity DataIC50: 36.8nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541379BDBM541379(US11267803, Example 27)
Affinity DataIC50: 37.4nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541397BDBM541397(US11267803, Example 45)
Affinity DataIC50: 38.5nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541374BDBM541374(US11267803, Example 22)
Affinity DataIC50: 40.3nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541367BDBM541367(US11267803, Example 15)
Affinity DataIC50: 46nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541355BDBM541355(US11267803, Example 3)
Affinity DataIC50: 47.2nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541380BDBM541380(US11267803, Example 28)
Affinity DataIC50: 55.3nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541375BDBM541375(US11267803, Example 23)
Affinity DataIC50: 59.6nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541381BDBM541381(US11267803, Example 29)
Affinity DataIC50: 63.1nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541393BDBM541393(US11267803, Example 41)
Affinity DataIC50: 68nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541399BDBM541399(US11267803, Example 47)
Affinity DataIC50: 78.2nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541364BDBM541364(US11267803, Example 12)
Affinity DataIC50: 81.1nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541372BDBM541372(US11267803, Example 20)
Affinity DataIC50: 90.1nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541385BDBM541385(US11267803, Example 33)
Affinity DataIC50: 110nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541359BDBM541359(US11267803, Example 7)
Affinity DataIC50: 138nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541373BDBM541373(US11267803, Example 21)
Affinity DataIC50: 142nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541383BDBM541383(US11267803, Example 31)
Affinity DataIC50: 144nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541384BDBM541384(US11267803, Example 32)
Affinity DataIC50: 146nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541368BDBM541368(US11267803, Example 16)
Affinity DataIC50: 155nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541371BDBM541371(US11267803, Example 19)
Affinity DataIC50: 157nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541398BDBM541398(US11267803, Example 46)
Affinity DataIC50: 181nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541361BDBM541361(US11267803, Example 9)
Affinity DataIC50: 199nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541387BDBM541387(US11267803, Example 35)
Affinity DataIC50: 223nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541353BDBM541353(US11267803, Example 1)
Affinity DataIC50: 261nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541382BDBM541382(US11267803, Example 30)
Affinity DataIC50: 303nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541390BDBM541390(US11267803, Example 38)
Affinity DataIC50: 523nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541394BDBM541394(US11267803, Example 42)
Affinity DataIC50: 606nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541386BDBM541386(US11267803, Example 34)
Affinity DataIC50: 620nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541358BDBM541358(US11267803, Example 6)
Affinity DataIC50: 675nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541395BDBM541395(US11267803, Example 43)
Affinity DataIC50: 1.18E+3nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541354BDBM541354(US11267803, Example 2)
Affinity DataIC50: 2.91E+3nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent