Compile Data Set for Download or QSAR
maximum 50k data
Found 96 Enz. Inhib. hit(s) with all data for entry = 10627
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552911(2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((4,4-di...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552939((R)-4-(4-((4,4-dimethyl-2-(3-methylbicyclo[1.1.1]p...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM50270877((R)-4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM60828(ABT-199 | BDBM189459 | US10213433, Compound 5 | US...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM555343((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552914(2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((4,4-di...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM555320(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((2-(3...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552934((R)-4-(4-((2-(3-chlorobicyclo[1.1.1]pentan-1-yl)-5...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552934((R)-4-(4-((2-(3-chlorobicyclo[1.1.1]pentan-1-yl)-5...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552931((R)-4-(4-((5,5-dimethyl-2-(3-methylbicyclo[1.1.1]p...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552931((R)-4-(4-((5,5-dimethyl-2-(3-methylbicyclo[1.1.1]p...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552935((R)-4-(4-((4,4-dimethyl-2-(3-methylbicyclo[1.1.1]p...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552935((R)-4-(4-((4,4-dimethyl-2-(3-methylbicyclo[1.1.1]p...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552936((R)-4-(4-((2-(3-Ethylbicyclo[1.1.1]pentan-1-yl)-4,...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552936((R)-4-(4-((2-(3-Ethylbicyclo[1.1.1]pentan-1-yl)-4,...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM555333((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM555333((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM555334((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM555334((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552939((R)-4-(4-((4,4-dimethyl-2-(3-methylbicyclo[1.1.1]p...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM50270877((R)-4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM555336((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM555336((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM555337((R)-4-(4-((2-(3-(Difluoromethyl)bicyclo[1.1.1]pent...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM555337((R)-4-(4-((2-(3-(Difluoromethyl)bicyclo[1.1.1]pent...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM555338((R)-4-(4-((2-(3-(Difluoromethyl)bicyclo[1.1.1]pent...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM555338((R)-4-(4-((2-(3-(Difluoromethyl)bicyclo[1.1.1]pent...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM555339((R)-4-(4-((2-(3-(Difluoromethyl)bicyclo[1.1.1]pent...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM555339((R)-4-(4-((2-(3-(Difluoromethyl)bicyclo[1.1.1]pent...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM555340((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM555340((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552945((R)-4-(4-((6-(3-(difluoromethyl)bicyclo[1.1.1]pent...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552945((R)-4-(4-((6-(3-(difluoromethyl)bicyclo[1.1.1]pent...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM555342((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM555342((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM555343((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...)
Affinity DataIC50: <10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM60828(ABT-199 | BDBM189459 | US10213433, Compound 5 | US...)
Affinity DataIC50:  55nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM555320(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((2-(3...)
Affinity DataIC50:  55nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552914(2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((4,4-di...)
Affinity DataIC50: >100nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552911(2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((4,4-di...)
Affinity DataIC50: >100nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552906(2-(1H-Pyrrolo[2,3-b]pyridin-5-yl-oxy)-4-(4-((2-(3-...)
Affinity DataKd: <10nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552906(2-(1H-Pyrrolo[2,3-b]pyridin-5-yl-oxy)-4-(4-((2-(3-...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552907(2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((4,4-di...)
Affinity DataKd: <10nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552907(2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((4,4-di...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552908(2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((2-(3-f...)
Affinity DataKd: <10nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552908(2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((2-(3-f...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552909(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-N-((4-(((7-...)
Affinity DataKd: <10nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552909(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-N-((4-(((7-...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552910(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4,4-...)
Affinity DataKd: <10nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Recurium Ip Holding

US Patent
LigandPNGBDBM552910(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4,4-...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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