Compile Data Set for Download or QSAR
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Found 6 Enz. Inhib. hit(s) with all data for entry = 10722
TargetCYP1A(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50051349(4-Methoxy-7-methyl-furo[3,2-g]chromen-5-one | CHEM...)
Affinity DataIC50:  240nMAssay Description:The ability of the tested compounds to inhibit a panel of CYP enzymes in vitro was assessed using a series of human liver microsome assays. Half-maxi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCYP1A(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM562067(US11396516, Example 2)
Affinity DataIC50:  1.60E+3nMAssay Description:The ability of the tested compounds to inhibit a panel of CYP enzymes in vitro was assessed using a series of human liver microsome assays. Half-maxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2D6(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM562067(US11396516, Example 2)
Affinity DataIC50:  2.00E+3nMAssay Description:The ability of the tested compounds to inhibit a panel of CYP enzymes in vitro was assessed using a series of human liver microsome assays. Half-maxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 3A43(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM562067(US11396516, Example 2)
Affinity DataIC50:  9.30E+3nMAssay Description:The ability of the tested compounds to inhibit a panel of CYP enzymes in vitro was assessed using a series of human liver microsome assays. Half-maxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C19(Homo sapiens)
The General Hospital

US Patent
LigandPNGBDBM562067(US11396516, Example 2)
Affinity DataIC50:  1.20E+4nMAssay Description:The ability of the tested compounds to inhibit a panel of CYP enzymes in vitro was assessed using a series of human liver microsome assays. Half-maxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2B6(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM562067(US11396516, Example 2)
Affinity DataIC50:  8.80E+4nMAssay Description:The ability of the tested compounds to inhibit a panel of CYP enzymes in vitro was assessed using a series of human liver microsome assays. Half-maxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent