Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 10875
TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 557699BDBM557699(US11466027, Compound 1l | US11358971, Compound 1h)
Affinity DataKi:  63nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 557694BDBM557694(US11466027, Compound 1e | US11358971, Compound 1c)
Affinity DataKi:  96nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 557693BDBM557693(US11466027, Compound 1d | US11358971, Compound 1b)
Affinity DataKi:  140nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 557667BDBM557667(US11466027, Compound 1c | US11358971, Compound 1a)
Affinity DataKi:  170nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 557701BDBM557701(US11466027, Compound 1n | US11358971, Compound 1j)
Affinity DataKi:  180nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 576021BDBM576021(US11466027, Compound 1f | (R)-2-amino-3-[(7- isopr...)
Affinity DataKi:  220nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 557698BDBM557698(US11466027, Compound 1k | US11358971, Compound 1g)
Affinity DataKi:  220nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 557702BDBM557702(US11466027, Compound 1o | US11358971, Compound 1k)
Affinity DataKi:  260nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 576017BDBM576017(US11466027, Compound 1b | (R)-2-amino-3-[(7- ethyl...)
Affinity DataKi:  270nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 557697BDBM557697(US11466027, Compound 1i | US11358971, Compound 1f)
Affinity DataKi:  360nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 557703BDBM557703(US11466027, Compound 1p | US11358971, Compound 1l)
Affinity DataKi:  490nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 557696BDBM557696(US11466027, Compound 1h | US11358971, Compound 1e)
Affinity DataKi:  690nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 557695BDBM557695(US11466027, Compound 1g | US11358971, Compound 1d)
Affinity DataKi:  860nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 576026BDBM576026(US11466027, Compound 1j | (R)-2-amino-3-[(7- ethox...)
Affinity DataKi:  870nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 557700BDBM557700(US11466027, Compound 1m | US11358971, Compound 1i)
Affinity DataKi:  3.90E+3nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 575980BDBM575980(US11466027, Compound 1a | (R)-2-amino-3-[[7- thien...)
Affinity DataKi:  7.40E+3nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent