Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 11097
TargetMitogen-activated protein kinase kinase kinase 12(Human)
University Of Texas

US Patent
LigandPNGBDBM590003((S)-1-(4-(6-amino-5- (trifluoromethyl)pyridin-3-yl...)
Affinity DataKd:  0.120nMAssay Description:A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 12(Human)
University Of Texas

US Patent
LigandPNGBDBM589995((R)-1-(4-(6-amino-5-(trifluoromethyl)pyridin-3-yl)...)
Affinity DataKd:  0.210nMAssay Description:A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 12(Human)
University Of Texas

US Patent
LigandPNGBDBM589991(US11560366, Example 3b)
Affinity DataKd:  0.240nMAssay Description:A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 12(Human)
University Of Texas

US Patent
LigandPNGBDBM590004((S)-1-(4-(6-amino-5- (trifluoromethoxy)pyridin-3-y...)
Affinity DataKd:  0.290nMAssay Description:A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 12(Human)
University Of Texas

US Patent
LigandPNGBDBM589992((S)-1-(4-(6-amino-5-(trifluoromethyl)pyridin-3-yl)...)
Affinity DataKd:  0.290nMAssay Description:A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 12(Human)
University Of Texas

US Patent
LigandPNGBDBM289483(US10093664, Example 59 | 1-(4-(6-amino-5- (trifluo...)
Affinity DataKd:  0.300nMAssay Description:A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 12(Human)
University Of Texas

US Patent
LigandPNGBDBM289428(US10093664, Example 8a | (S)-1-(4-(6-amino-5-(trif...)
Affinity DataKd:  0.360nMAssay Description:A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 12(Human)
University Of Texas

US Patent
LigandPNGBDBM589996((R)-1-(4-(6-amino-5-(trifluoromethoxy)pyridin-3-yl...)
Affinity DataKd:  0.5nMAssay Description:A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 12(Human)
University Of Texas

US Patent
LigandPNGBDBM589998(US11560366, Example 10a)
Affinity DataKd:  0.620nMAssay Description:A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 12(Human)
University Of Texas

US Patent
LigandPNGBDBM589997(US11560366, Example 9b)
Affinity DataKd:  1nMAssay Description:A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 12(Human)
University Of Texas

US Patent
LigandPNGBDBM590001((R)-1-(4-(6-amino-5-(trifluoromethoxy)- pyridin-3-...)
Affinity DataKd:  1.60nMAssay Description:A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 12(Human)
University Of Texas

US Patent
LigandPNGBDBM589988(US11560366, Example 1a | (R)-1-(4-(6-amino-5-(trif...)
Affinity DataKd:  2.20nMAssay Description:A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 12(Human)
University Of Texas

US Patent
LigandPNGBDBM590000((4-(6-amino-5-(trifluoromethyl)pyridin-3-yl)-1-(3-...)
Affinity DataKd:  2.90nMAssay Description:A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 12(Human)
University Of Texas

US Patent
LigandPNGBDBM589999((4-(6-amino-5-(trifluoromethoxy)pyridin-3-yl)-1-(3...)
Affinity DataKd:  3.10nMAssay Description:A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 12(Human)
University Of Texas

US Patent
LigandPNGBDBM589990((R)-1-(4-(6-amino-5-(trifluoromethyl)pyridin-3-yl)...)
Affinity DataKd:  4.40nMAssay Description:A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 12(Human)
University Of Texas

US Patent
LigandPNGBDBM589993(US11560366, Example 5)
Affinity DataKd:  5.20nMAssay Description:A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 12(Human)
University Of Texas

US Patent
LigandPNGBDBM589994(US11560366, Example 6)
Affinity DataKd:  7.70nMAssay Description:A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 12(Human)
University Of Texas

US Patent
LigandPNGBDBM589988(US11560366, Example 1a | (R)-1-(4-(6-amino-5-(trif...)
Affinity DataKd:  120nMAssay Description:A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent